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What is DNA imputation and why do I need it?

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DNA imputation is an advanced service that dramatically expands your genetic data:

What is Imputation?

Imputation uses statistical algorithms and large reference populations to predict ("impute") genetic markers that weren't directly tested by your DNA company.

  • Your original file: ~600,000 - 700,000 SNPs
  • After imputation: 30+ million SNPs
  • Increase: 40-50x more genetic information!
Why You Need Imputation:
  • Enhanced Analysis: Access to reports requiring more markers
  • Better Accuracy: More data points = more precise results
  • Compatibility: Work with tools requiring high-density data
  • Research: Participate in studies needing comprehensive data
  • Medical Insights: Analyze health markers not on consumer chips
  • Rare Variants: Discover less common genetic variations
How It Works:
  1. Upload your standard DNA file
  2. Purchase imputation service
  3. Our algorithms compare your data to reference populations
  4. Statistical models predict missing SNPs with high accuracy
  5. Receive expanded file in 24-72 hours
What You Get:
  • Extended RAW file with 30+ million SNPs
  • Compatible with all our reports and tools
  • Downloadable for use on other platforms
  • Significantly improved analysis capabilities
Accuracy:
  • Imputation accuracy: 95-99% depending on ancestry
  • Based on large reference panels (1000 Genomes, HapMap, etc.)
  • Best for European, Asian, African ancestries
  • Works with all standard consumer DNA files
Included in Explorer Pack:

The imputation service is included with our Explorer Pack, along with numerous reports and tools.


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