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DNA PHASING SERVICE

Separate Your DNA Into Maternal & Paternal Lines

Discover which traits and ancestries you inherited from each parent. Our phasing service creates two separate files - one for each parental contribution - enabling deeper genealogical insights and clearer family connections.

28.00€
Starting price Includes Starter Pack
Separate maternal/paternal
Up to 99% accuracy (with parents)
~48h turnaround
Phasing Visualization
Your DNA
Mixed maternal + paternal
Parent 1
Maternal Line
Parent 2
Paternal Line

What is DNA Phasing?

Understanding Phasing

You inherit 50% of your DNA from each parent. Through phasing, we create two separate RAW files, each representing the genetic contribution from one parent. This allows you to determine which traits or ancestries you inherited from your maternal or paternal side.

DNA phasing is particularly valuable for ancestry and genetic genealogy because it allows you to determine the specific ancestry and DNA matches that you inherited from each parent. This separation provides clearer insights into your family history.

Important Note

In Duo or Trio phasing, the phased files contain only the shared SNPs between the child's file and the parents' files. SNPs that are not shared cannot be phased. We strongly recommend using the same testing company for the child and the parents for best results.

Phasing Options

Choose the method that works best for your situation

Statistical
~90% Accuracy

Phasing Without Parents

Uses population-level haplotype patterns to statistically separate your chromosomes into maternal and paternal contributions.

  • Separate maternal/paternal DNA
  • No parental samples needed
  • Some ancestry noise expected
Duo
~98% Accuracy

Child + One Parent

With one parent's DNA, we can definitively assign which chromosomes came from that parent and which from the other.

  • Precise parent identification
  • 99% separated ancestry
  • Parent 1 = provided parent
Trio
~99% Accuracy

Child + Both Parents

With both parents' DNA, achieve the highest possible accuracy for complete parental separation.

  • Complete parental separation
  • Near-complete ancestry accuracy
  • Highest precision possible

How It Works

Simple three-step process to separate your parental DNA

Phasing Workflow
Share Your Files
Upload RAW files
Child + parents
Specify Options
Choose phasing type
Statistical/Duo/Trio
Receive Results
Two phased files
~48 hours

What Happens Inside the Pipeline

The statistical phasing pipeline runs on research-grade bioinformatics infrastructure. Here's what actually runs when you submit a file.

Statistical Phasing Workflow
Input File
Your raw DNA data
Any major provider
Pre-processing
VCF conversion & filters
Remove Y/MT, fix ploidy
Beagle Phasing
1KG - HG19 + HG38
Chr 1-22 + X, both builds
Haplotype Split
VCF → parental RAW files
One file per haplotype
Merge with Original
Homozygous SNPs added back
RawDnaMerger
Output Files
Parent 1 + Parent 2
Two RAW ZIP files
Technical Deep Dive For Researchers

Pre-processing

The input build (HG19 or HG38) is auto-detected and the raw file is converted to VCF against the matching reference. Three normalisation filters run before Beagle sees any data.

  • Y and MT chromosomes removed
  • Haploid calls normalised to diploid
  • Isolated edge markers trimmed

Phasing Engine

Beagle 5.4 runs in phasing-only mode (impute=false) per chromosome against the 1000 Genomes Phase 3 reference panel.

  • 1KG Phase 3 bref3 reference
  • GRCh37 and GRCh38 genetic maps
  • Chr 1-22 + X phased

Post-phasing Merge

Each phased VCF is split into two parental haplotype RAW files. Homozygous SNPs from the original file are added back; remaining heterozygous calls are set to no-call.

  • Per-haplotype RAW conversion
  • Homozygous SNPs re-merged
  • Unresolvable hets → no-call

Reference Panel

The reference panel provides the haplotype templates used to statistically infer parental contributions.

  • 1000 Genomes Phase 3
  • 2,504 individuals, 26 populations
  • GRCh37 (hg19) and GRCh38 (hg38)
# Statistical phasing workflow
Input: raw_genotypes.txt (HG19 or HG38 auto-detected)
Step 1: Convert to VCF against matching reference; remove Y/MT; normalise ploidy; trim edge markers
Step 2: Phase with Beagle 5.4 (impute=false) against 1000G in HG19 and HG38 (chr 1-22 + X)
Step 3: Split phased VCFs into Parent1 and Parent2 haplotype RAW files
Step 4: Merge parental files with homozygous SNPs from original sample
Step 5: Set remaining heterozygous genotypes to no-call
Output: Parent1.zip + Parent2.zip (both HG19 and HG38)

Supported DNA Test Providers

Provider names describe file compatibility only; no affiliation or endorsement is implied.

AncestryDNA 23andMe MyHeritage FamilyTreeDNA LivingDNA WeGene Nebula Genomics Dante Labs 24Genetics

What You'll Receive

Service Includes

  • Two phased RAW files (Parent 1, Parent 2)
  • Starter Pack for each phased file
  • Processing within 48 hours
  • Comprehensive parental ancestry insights

Usage Scenarios

  • DNAGENICS Analysis - separate reports per parent
  • Ancestry Research - distinct maternal/paternal breakdown
  • Genealogy - clearer DNA match assignments
  • Third-party platforms - GEDmatch, MyTrueAncestry

Service Options

Choose your phasing method

Phasing Without Parents

28.00€
One-time payment
30% off with code: DISCOUNT30
  • Statistical phasing (~90% accuracy)
  • Two separate parental files
  • Starter Pack included
  • Fast processing (~48h)
  • Secure handling
  • Technical support
Order Now
Most Accurate

Phasing With Parents

28.00€
One-time payment
30% off with code: DISCOUNT30
  • Duo/Trio phasing (up to 99%)
  • Two separate parental files
  • Starter Pack included
  • Fast processing (~48h)
  • Secure handling
  • Technical support
Order Now

Frequently Asked Questions

Why do I need to test my parents when I can phase my own DNA?

Each phased file contains only the portion inherited from that parent. Testing a parent directly is still required to obtain genetic information that was not inherited by the child.

What determines Parent 1 versus Parent 2?

In Duo Phasing, Parent 1 is the parent whose raw file is provided. In Trio Phasing, the labels follow file selection order. Without parent files, the two labels are arbitrary.

What about shared SNPs?

Duo and Trio outputs include SNPs available in both the child's and the relevant parent files. Using files with greater marker overlap can improve usable coverage.

Can I rephase a previously phased file?

No. Use the original unphased raw file for a new phasing request because a phased output represents one inferred haplotype.

Things to Know

Technical Details

  • Accepts HG19 (GRCh37) and HG38 (GRCh38) input files; build is auto-detected
  • Phased output files are delivered in both HG19 and HG38
  • Phasing covers chromosomes 1-22 and X
  • Process takes up to 48 hours
  • Best results when all tests are from the same company
  • For ancestry and genealogy purposes only
  • Once phased, files cannot be rephased

Legal Information

Start Your DNA Phasing Today

Discover your parental genetic heritage with separated maternal and paternal files