Mephisto K10

Mephisto K10 — Ancient-era admixture calculator

This tool estimates how an individual's genome decomposes into ten ancient reference components spanning the Near East, Anatolia, Europe and the Steppe. It was trained on archeogenetic clusters from the Neolithic through Chalcolithic and Bronze Age, and reports relative ancestry proportions from: Levant_N, Anatolia_N, Hungar_EN, LBK, Iran_N, Spain_EN, Sintashta, Armenia_CH, Steppes, Pre_CH_Armenia.

What this calculator analyzes

• Genome-wide allele sharing against ten ancient populations representative of major prehistoric migrations and local continuities.
• Broad-scale admixture signals (e.g., farmer vs. steppe vs. Iranian-related inputs) and relative strengths of regional ancestries.

Who it's designed for

• Researchers, students, hobby genetic genealogists, museum professionals and anyone curious about how ancient demography shaped modern genomes.
• Suitable for global samples — modern or ancient — to place individuals on major prehistoric clines.

Insights you can gain

• Proportional ancestry from major ancient sources (Neolithic farmers, steppe pastoralists, Chalcolithic/early Bronze Age groups).
• Signals of migration, admixture timing hypotheses (when combined with other analyses), and regionally informative contrasts (e.g., Anatolian vs. Iranian vs. Levantine inputs).

Historical and genetic context

• Components represent key prehistoric processes: the spread of agriculture from Anatolia/Levant, local European Neolithic variation (LBK, Hungar_EN, Spain_EN), Iranian-related ancestry, and later steppe-derived movements (Sintashta/Steppe). Inclusion of Armenia_CH and Pre_CH_Armenia provides resolution in the South Caucasus and eastern Anatolian interactions.

Why Mephisto K10 is valuable

• Provides an interpretable, reproducible 10-way breakdown tailored to Ancient-era questions.
• Helps users visualize complex ancestry in an accessible format while linking patterns to archaeological migration mode