Genetic Tendency

Based on your genetic markers, your tendency toward this trait is shown below

Your Result

You have one copy of A1298C, gen MTHFR

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Scientific Evidence

Understanding the Data
  • SNP: A specific genetic marker relevant to this trait (e.g., rs2588978)
  • Genotype: Your genetic makeup at the given SNP location (e.g., CC)
  • Variant allele: The alternative DNA sequence at the SNP site
  • Variant allele frequency: Percentage of population carrying this variant
  • Variant found: Whether the variant was detected in your DNA file
1 gene analyzed 1 with detected variants
Variant Detected

MTHFR GeneCards

The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.[provided by RefSeq, Oct 2009]

Genomic Location
Chr 1 Start: 11,785,723 End: 11,806,455 Build: HG19
Associated SNPs
1 / 1 detected
SNP Genotype Ref. Allele Variant Allele Frequency Status

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Coverage: 3/3 SNPs detected (100%)
Reference: Human Genome Build 37 (HG19)
Generated: May 15, 2026
DNA Genics reports genotypes based on the 'positive' strand of the human genome reference sequence. Other testing companies may report using the opposite strand, requiring conversion for accurate comparison.