Active: Lymphocyte count Clear all

GWAS 2023-03-17

Interplay Between Hereditary and Acquired Factors Determine Neutrophil Counts in Aging Individuals.

Gagnon MF, Provost S et al.

Blood Adv

Blood cell production is a complex process, partly genetically determined and influenced by acquired...

White blood cell count

2465

Participants

N/A

Studies

Details PubMed

GWAS 2022-05-10

Genetic variation in ST6GAL1 is a determinant of capecitabine and oxaliplatin induced hand-foot syndrome.

Watts K, Wills C et al.

Int J Cancer

Cancer patients treated with capecitabine and oxaliplatin (XELOX) often develop hand-foot syndrome (...

Adverse response to chemotherapy in colorectal cancer (XELOX) (Peripheral Neuropathy)

1055

Participants

N/A

Studies

Details PubMed

GWAS 2021-12-02

Genome-Wide Association and Mendelian Randomization Analysis Reveal the Causal Relationship Between White Blood Cell Subtypes and Asthma in Africans.

Soremekun O, Soremekun C et al.

Front Genet

White blood cell (WBC) traits and their subtypes such as basophil count (Bas), eosinophil count (Eos...

Monocyte count

16152

Participants

N/A

Studies

Details PubMed

GWAS 2021-09-27

Whole-genome sequencing in diverse subjects identifies genetic correlates of leukocyte traits: The NHLBI TOPMed program.

Mikhaylova AV, McHugh CP et al.

Am J Hum Genet

Many common and rare variants associated with hematologic traits have been discovered through imputa...

White blood cell count

Replicated

260928

Participants

N/A

Studies

Details PubMed

GWAS 2021-08-26

Genetic determinants of blood-cell traits influence susceptibility to childhood acute lymphoblastic leukemia.

Kachuri L, Jeon S et al.

Am J Hum Genet

Acute lymphoblastic leukemia (ALL) is the most common childhood cancer. Despite overlap between gene...

Acute lymphoblastic leukemia

Replicated

60538

Participants

N/A

Studies

Details PubMed

GWAS 2020-09-01

Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations.

Chen MH, Raffield LM et al.

Cell

Most loci identified by GWASs have been found in populations of European ancestry (EUR). In trans-et...

Basophil count

11502

Participants

N/A

Studies

Details PubMed

GWAS 2020-08-26

Genome-wide Study Identifies Association between HLA-B∗55:01 and Self-Reported Penicillin Allergy.

Krebs K, Bovijn J et al.

Am J Hum Genet

Hypersensitivity reactions to drugs are often unpredictable and can be life threatening, underscorin...

Penicillin allergy

Replicated

1600573

Participants

N/A

Studies

Details PubMed

GWAS 2019-11-04

Genetic Study of Severe Prolonged Lymphopenia in Multiple Sclerosis Patients Treated With Dimethyl Fumarate.

Sangurdekar D, Sun C et al.

Front Genet

In delayed-release dimethyl fumarate (DMF)-treated patients, absolute lymphocyte count (ALC) often d...

Severe prolonged lymphopenia in dimethyl fumarate-treated relapsing-remitting multiple sclerosis

1094

Participants

N/A

Studies

Details PubMed

GWAS 2017-09-11

Genome-wide association study identifies 112 new loci for body mass index in the Japanese population.

Akiyama M, Okada Y et al.

Nat Genet

Obesity is a risk factor for a wide variety of health problems. In a genome-wide association study (...

Body mass index

Replicated

495584

Participants

N/A

Studies

Details PubMed

GWAS 2017-02-14

Heritability and GWAS Studies for Monocyte-Lymphocyte Ratio.

Lin BD, Willemsen G et al.

Twin Res Hum Genet

The monocyte-lymphocyte ratio (MLR) is a useful biomarker for disease development, but little is kno...

Monocyte-lymphocyte ratio

5892

Participants

N/A

Studies

Details PubMed

GWAS 2012-01-27

The combination of a genome-wide association study of lymphocyte count and analysis of gene expression data reveals novel asthma candidate genes.

Cusanovich DA, Billstrand C et al.

Hum Mol Genet

Recent genome-wide association studies (GWAS) have identified a number of novel genetic associations...

Lymphocyte count

462

Participants

N/A

Studies

Details PubMed

GWAS 2011-07-01

Multiple loci are associated with white blood cell phenotypes.

Nalls MA, Couper DJ et al.

PLoS Genet

White blood cell (WBC) count is a common clinical measure from complete blood count assays, and it v...

White blood cell count

Replicated

31332

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Interplay Between Hereditary and Acquired Factors Determine Neutrophil Counts in Aging Individuals.

Gagnon MF, Provost S et al.

Blood Adv

White blood cell count

2023-03-17

Genetic variation in ST6GAL1 is a determinant of capecitabine and oxaliplatin induced hand-foot syndrome.

Watts K, Wills C et al.

Int J Cancer

Adverse response to chemotherapy in colorectal cancer (XELOX) (Peripheral Neuropathy)

2022-05-10

Genome-Wide Association and Mendelian Randomization Analysis Reveal the Causal Relationship Between White Blood Cell Subtypes and Asthma in Africans.

Soremekun O, Soremekun C et al.

Front Genet

Monocyte count

2021-12-02

Whole-genome sequencing in diverse subjects identifies genetic correlates of leukocyte traits: The NHLBI TOPMed program.

Mikhaylova AV, McHugh CP et al.

Am J Hum Genet

White blood cell count

2021-09-27

Genetic determinants of blood-cell traits influence susceptibility to childhood acute lymphoblastic leukemia.

Kachuri L, Jeon S et al.

Am J Hum Genet

Acute lymphoblastic leukemia

2021-08-26

Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations.

Chen MH, Raffield LM et al.

Cell

Basophil count

2020-09-01

Genome-wide Study Identifies Association between HLA-B∗55:01 and Self-Reported Penicillin Allergy.

Krebs K, Bovijn J et al.

Am J Hum Genet

Penicillin allergy

2020-08-26

Genetic Study of Severe Prolonged Lymphopenia in Multiple Sclerosis Patients Treated With Dimethyl Fumarate.

Sangurdekar D, Sun C et al.

Front Genet

Severe prolonged lymphopenia in dimethyl fumarate-treated relapsing-remitting multiple sclerosis

2019-11-04

Genome-wide association study identifies 112 new loci for body mass index in the Japanese population.

Akiyama M, Okada Y et al.

Nat Genet

Body mass index

2017-09-11

Heritability and GWAS Studies for Monocyte-Lymphocyte Ratio.

Lin BD, Willemsen G et al.

Twin Res Hum Genet

Monocyte-lymphocyte ratio

2017-02-14

The combination of a genome-wide association study of lymphocyte count and analysis of gene expression data reveals novel asthma candidate genes.

Cusanovich DA, Billstrand C et al.

Hum Mol Genet

Lymphocyte count

2012-01-27

Multiple loci are associated with white blood cell phenotypes.

Nalls MA, Couper DJ et al.

PLoS Genet

White blood cell count

2011-07-01