Genetic Predisposition

Based on your genetic markers, your predisposition to this trait is shown below

Your Result

Increased likelihood of lactose intolerant in adults

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Scientific Evidence

Understanding the Data
  • SNP: A specific genetic marker relevant to this trait (e.g., rs2588978)
  • Genotype: Your genetic makeup at the given SNP location (e.g., CC)
  • Variant allele: The alternative DNA sequence at the SNP site
  • Variant allele frequency: Percentage of population carrying this variant
  • Variant found: Whether the variant was detected in your DNA file
1 gene analyzed 1 with detected variants
Variant Detected

MCM6 GeneCards

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication. Single nucleotide polymorphisms in the intron regions of this gene are associated with differential transcriptional activation of the promoter of the neighboring lactase gene and, thereby, influence lactose intolerance in early adulthood. [provided by RefSeq, May 2012]

Genomic Location
Chr 2 Start: 135,839,626 End: 135,876,443 Build: HG19
Associated SNPs
2 / 2 detected
SNP Genotype Ref. Allele Variant Allele Frequency Status

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Coverage: 6/6 SNPs detected (100%)
Reference: Human Genome Build 37 (HG19)
Generated: March 02, 2026
DNA Genics reports genotypes based on the 'positive' strand of the human genome reference sequence. Other testing companies may report using the opposite strand, requiring conversion for accurate comparison.