DNA Coordinate Liftover
Convert your RAW or VCF DNA file between the HG19/GRCh37 and HG38/GRCh38 reference genome builds. We detect the source build automatically and deliver your file in the opposite build, ready for downstream tools that expect a specific reference.
Key Features
Reliable, predictable coordinate liftover with a privacy-first workflow.
Auto-Detected Source Build
Upload a RAW or VCF file in either HG19/GRCh37 or HG38/GRCh38. We detect the build and deliver the file in the opposite reference genome.
Fast Turnaround
Most conversions complete within ~24 hours. Your lifted file is delivered through a secure, account-gated download workflow.
Secure Handling
Your genetic data is processed only for your order, never sold or shared, and delivered privately to your account.
Technical Specifications
Clear expectations for inputs, outputs, and intended use.
Input
A RAW DNA file from a major DTC provider, or a VCF file. Either HG19/GRCh37 or HG38/GRCh38 is accepted.
Output
Your file lifted into the opposite reference build. RAW inputs return as a canonical 23andMe-style RAW (zipped); VCF inputs return as a bgzipped, tabix-indexed VCF.
Intended Use
Designed for research and personal exploration workflows that require a specific reference genome build. Not intended for clinical or medical decisions.
How It Works
A simple three-step process from upload to delivery.
Share Your File
Pick the sample you want to lift in the checkout flow. RAW and VCF are both supported.
Auto-Detect & Liftover
We detect the source reference build, lift the coordinates to the opposite build, and validate the output.
Secure Delivery
Your lifted RAW or VCF file appears in your Products area and you receive an email notification.
Important Information
A few practical notes to set expectations.
What Liftover Does
Liftover remaps the genomic coordinates of your variants from one reference build to another. Variants that cannot be unambiguously mapped between builds are excluded from the output.
Not for Medical Decisions
This service is intended for research and educational use. Do not use lifted files for clinical diagnosis or medical decisions.
Simple Pricing
One order includes liftover and secure delivery. No subscription.
DNA Coordinate Liftover
- Lift one RAW or VCF file between HG19 / HG38
- Source build auto-detected
- Standardized output (RAW or bgzipped/indexed VCF)
- Secure delivery
- Email support
Frequently Asked Questions
Common questions about DNA coordinate liftover.
What is a reference genome build?
How do I know which build my file is in?
Which file formats do you support?
Will I lose any variants in the liftover?
How long does it take?
Is my data private?
Can I use this for medical interpretation?
Legal notice: This service is intended for ancestry/genealogy and research use. The service is provided "as is" without warranties. You are responsible for any third-party usage of generated files.
Lift Your DNA File Between HG19 and HG38
Get a standardized lifted output for imputation panels, reference comparison, and downstream workflows.
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