Genetic Predisposition

Based on your genetic markers, your predisposition to this trait is shown below

Your Result

Higher Triglyceride levels

Was this result accurate for you?

Scientific Evidence

Understanding the Data
  • SNP: A specific genetic marker relevant to this trait (e.g., rs2588978)
  • Genotype: Your genetic makeup at the given SNP location (e.g., CC)
  • Variant allele: The alternative DNA sequence at the SNP site
  • Variant allele frequency: Percentage of population carrying this variant
  • Variant found: Whether the variant was detected in your DNA file
31 genes analyzed 4 with detected variants
Variant Detected

GCKR GeneCards

This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY).

Genomic Location
Chr 2 Start: 27,719,706 End: 27,746,551 Build: HG19
Associated SNPs
1 / 1 detected
SNP Genotype Ref. Allele Variant Allele Frequency Status
Variant Detected

NOX4 GeneCards

NADPH oxidase 4

Genomic Location
Chr 11 Start: 89,057,521 End: 89,322,725 Build: HG19
Associated SNPs
1 / 1 detected
SNP Genotype Ref. Allele Variant Allele Frequency Status
Variant Detected

SNX17 GeneCards

sorting nexin 17

Genomic Location
Chr 2 Start: 27,593,483 End: 27,600,402 Build: HG19
Associated SNPs
1 / 1 detected
SNP Genotype Ref. Allele Variant Allele Frequency Status
Variant Detected

WNT4 GeneCards

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family, and is the first signaling molecule shown to influence the sex-determination cascade. It encodes a protein which shows 98% amino acid identity to the Wnt4 protein of mouse and rat. This gene and a nuclear receptor known to antagonize the testis-determining factor play a concerted role in both the control of female development and the prevention of testes formation. This gene and another two family members, WNT2 and WNT7B, may be associated with abnormal proliferation in breast tissue. Mutations in this gene can result in Rokitansky-Kuster-Hauser syndrome and in SERKAL syndrome.

Genomic Location
Chr 1 Start: 22,443,806 End: 22,469,590 Build: HG19
Associated SNPs
1 / 1 detected
SNP Genotype Ref. Allele Variant Allele Frequency Status

AFF3 GeneCards

This gene encodes a tissue-restricted nuclear transcriptional activator that is preferentially expressed in lymphoid tissue. Isolation of this protein initially defined a highly conserved LAF4/MLLT2 gene family of nuclear transcription factors that may function in lymphoid development and oncogenesis. In some ALL patients, this gene has been found fused to the gene for MLL. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.

Genomic Location
Chr 2 Start: 100,161,881 End: 100,759,052 Build: HG19
Associated SNPs
0 / 1 detected
SNP Genotype Ref. Allele Variant Allele Frequency Status

AQP1 GeneCards

This gene encodes a small integral membrane protein with six bilayer spanning domains that functions as a water channel protein. This protein permits passive transport of water along an osmotic gradient. This gene is a possible candidate for disorders involving imbalance in ocular fluid movement.

Genomic Location
Chr 7 Start: 30,951,468 End: 30,965,131 Build: HG19
Associated SNPs
0 / 1 detected
SNP Genotype Ref. Allele Variant Allele Frequency Status

BTBD11 GeneCards

BTB domain containing 11

Genomic Location
Chr 12 Start: 107,712,211 End: 108,053,419 Build: HG19
Associated SNPs
0 / 1 detected
SNP Genotype Ref. Allele Variant Allele Frequency Status

FAM189A1 GeneCards

family with sequence similarity 189 member A1

Genomic Location
Chr 15 Start: 29,409,915 End: 29,967,613 Build: HG19
Associated SNPs
0 / 1 detected
SNP Genotype Ref. Allele Variant Allele Frequency Status
Genomic Location
Chr 1 Start: 231,154,704 End: 231,176,000 Build: HG19
Associated SNPs
0 / 1 detected
SNP Genotype Ref. Allele Variant Allele Frequency Status

GHRHR GeneCards

This gene encodes a receptor for growth hormone-releasing hormone. Binding of this hormone to the receptor leads to synthesis and release of growth hormone. Mutations in this gene have been associated with isolated growth hormone deficiency (IGHD), also known as Dwarfism of Sindh, a disorder characterized by short stature.

Genomic Location
Chr 7 Start: 31,003,568 End: 31,019,143 Build: HG19

No SNPs found for this gene in your DNA data.

GJA5 GeneCards

This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene may be associated with atrial fibrillation. Alternatively spliced transcript variants encoding the same isoform have been described.

Genomic Location
Chr 1 Start: 147,228,332 End: 147,245,455 Build: HG19
Associated SNPs
0 / 1 detected
SNP Genotype Ref. Allele Variant Allele Frequency Status

GJA8 GeneCards

This gene encodes a transmembrane connexin protein that is necessary for lens growth and maturation of lens fiber cells. The encoded protein is a component of gap junction channels and functions in a calcium and pH-dependent manner. Mutations in this gene have been associated with zonular pulverulent cataracts, nuclear progressive cataracts, and cataract-microcornea syndrome.

Genomic Location
Chr 1 Start: 147,374,921 End: 147,381,396 Build: HG19

No SNPs found for this gene in your DNA data.

Genomic Location
Chr 3 Start: 115,521,221 End: 116,164,334 Build: HG19
Associated SNPs
0 / 1 detected
SNP Genotype Ref. Allele Variant Allele Frequency Status

MAN2A1 GeneCards

mannosidase alpha class 2A member 1

Genomic Location
Chr 5 Start: 109,025,628 End: 109,205,326 Build: HG19

No SNPs found for this gene in your DNA data.

Genomic Location
Chr 6 Start: 44,081,188 End: 44,095,189 Build: HG19

No SNPs found for this gene in your DNA data.

PCDH7 GeneCards

protocadherin 7

Genomic Location
Chr 4 Start: 30,721,991 End: 31,148,422 Build: HG19
Associated SNPs
0 / 1 detected
SNP Genotype Ref. Allele Variant Allele Frequency Status
Genomic Location
Chr 5 Start: 108,670,423 End: 108,745,675 Build: HG19
Associated SNPs
0 / 2 detected
SNP Genotype Ref. Allele Variant Allele Frequency Status

PTPRD GeneCards

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of three Ig-like and eight fibronectin type III-like domains. Studies of the similar genes in chicken and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance. Multiple alternatively spliced transcript variants of this gene have been reported. A related pseudogene has been identified on chromosome 5.

Genomic Location
Chr 9 Start: 8,314,246 End: 10,613,002 Build: HG19
Associated SNPs
0 / 1 detected
SNP Genotype Ref. Allele Variant Allele Frequency Status
Genomic Location
Chr 10 Start: 134,210,704 End: 134,231,363 Build: HG19
Associated SNPs
0 / 1 detected
SNP Genotype Ref. Allele Variant Allele Frequency Status
Genomic Location
Chr 3 Start: 8,918,759 End: 9,005,156 Build: HG19

No SNPs found for this gene in your DNA data.

RBFOX1 GeneCards

The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Fox-1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox-1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Genomic Location
Chr 16 Start: 6,069,025 End: 7,763,342 Build: HG19

No SNPs found for this gene in your DNA data.

Genomic Location
Chr 10 Start: 10,826,402 End: 10,836,877 Build: HG19

No SNPs found for this gene in your DNA data.

TCF3 GeneCards

This gene encodes a member of the E protein (class I) family of helix-loop-helix transcription factors. E proteins activate transcription by binding to regulatory E-box sequences on target genes as heterodimers or homodimers, and are inhibited by heterodimerization with inhibitor of DNA-binding (class IV) helix-loop-helix proteins. E proteins play a critical role in lymphopoiesis, and the encoded protein is required for B and T lymphocyte development. Deletion of this gene or diminished activity of the encoded protein may play a role in lymphoid malignancies. This gene is also involved in several chromosomal translocations that are associated with lymphoid malignancies including pre-B-cell acute lymphoblastic leukemia (t(1

Genomic Location
Chr 19 Start: 1,609,291 End: 1,652,614 Build: HG19
Associated SNPs
0 / 1 detected
SNP Genotype Ref. Allele Variant Allele Frequency Status

TMEM132D GeneCards

transmembrane protein 132D

Genomic Location
Chr 12 Start: 129,556,271 End: 130,388,570 Build: HG19
Associated SNPs
0 / 1 detected
SNP Genotype Ref. Allele Variant Allele Frequency Status

TOM1 GeneCards

target of myb1 membrane trafficking protein

Genomic Location
Chr 22 Start: 35,695,268 End: 35,743,966 Build: HG19
Associated SNPs
0 / 1 detected
SNP Genotype Ref. Allele Variant Allele Frequency Status
Genomic Location
Chr 1 Start: 231,297,804 End: 231,357,311 Build: HG19

No SNPs found for this gene in your DNA data.

WWOX GeneCards

This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) protein family. This gene spans the FRA16D common chromosomal fragile site and appears to function as a tumor suppressor gene. Expression of the encoded protein is able to induce apoptosis, while defects in this gene are associated with multiple types of cancer. Disruption of this gene is also associated with autosomal recessive spinocerebellar ataxia 12. Disruption of a similar gene in mouse results in impaired steroidogenesis, additionally suggesting a metabolic function for the protein. Alternative splicing results in multiple transcript variants.

Genomic Location
Chr 16 Start: 78,133,551 End: 79,246,564 Build: HG19
Associated SNPs
0 / 1 detected
SNP Genotype Ref. Allele Variant Allele Frequency Status
Genomic Location
Chr 3 Start: 149,235,022 End: 149,442,575 Build: HG19
Associated SNPs
0 / 1 detected
SNP Genotype Ref. Allele Variant Allele Frequency Status

ZBTB40 GeneCards

zinc finger and BTB domain containing 40

Genomic Location
Chr 1 Start: 22,778,344 End: 22,857,647 Build: HG19

No SNPs found for this gene in your DNA data.

ZNF571 GeneCards

zinc finger protein 571

Genomic Location
Chr 19 Start: 38,055,162 End: 38,085,693 Build: HG19
Associated SNPs
0 / 1 detected
SNP Genotype Ref. Allele Variant Allele Frequency Status

ZNF862 GeneCards

zinc finger protein 862

Genomic Location
Chr 7 Start: 149,535,464 End: 149,564,568 Build: HG19
Associated SNPs
0 / 1 detected
SNP Genotype Ref. Allele Variant Allele Frequency Status

What's Next?

Compare Samples

Compare this trait across different samples in your account

Compare
Print Report

Download or print this report for your records

Explore More Traits

Discover insights about other genetic traits

Browse Traits
Coverage: 4/33 SNPs detected (12%)
Reference: Human Genome Build 37 (HG19)
Generated: March 02, 2026
DNA Genics reports genotypes based on the 'positive' strand of the human genome reference sequence. Other testing companies may report using the opposite strand, requiring conversion for accurate comparison.