Genetic Predisposition
Based on your genetic markers, your predisposition to this trait is shown below
Your Result
Lower Autism spectrum disorder predisposition
Was this result accurate for you?
Scientific Evidence
Understanding the Data
- SNP: A specific genetic marker relevant to this trait (e.g., rs2588978)
- Genotype: Your genetic makeup at the given SNP location (e.g., CC)
- Variant allele: The alternative DNA sequence at the SNP site
- Variant allele frequency: Percentage of population carrying this variant
- Variant found: Whether the variant was detected in your DNA file
CADPS GeneCards
This gene encodes a novel neural/endocrine-specific cytosolic and peripheral membrane protein required for the Ca2+-regulated exocytosis of secretory vesicles. The protein acts at a stage in exocytosis that follows ATP-dependent priming, which involves the essential synthesis of phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Alternative splicing has been observed at this locus and three variants, encoding distinct isoforms, are described.
Genomic Location
Associated SNPs
| SNP | Genotype | Ref. Allele | Variant Allele | Frequency | Status |
|---|---|---|---|---|---|
| rs1452075 | T T | C | T | 72.10% | Detected |
C8orf74 GeneCards
Genomic Location
Associated SNPs
| SNP | Genotype | Ref. Allele | Variant Allele | Frequency | Status |
|---|---|---|---|---|---|
| rs10099100 | -- | G | C | 33.10% | No Data |
KIZ GeneCards
The protein encoded by this gene localizes to centrosomes, strengthening and stabilizing the pericentriolar region prior to spindle formation. The encoded protein usually remains with the mother centrosome after centrosomal duplication. Sevral transcript variants encoding different isoforms have been found for this gene.
Genomic Location
Associated SNPs
| SNP | Genotype | Ref. Allele | Variant Allele | Frequency | Status |
|---|---|---|---|---|---|
| rs910805 | -- | G | A | 24.00% | No Data |
KMT2E GeneCards
This gene is a member of the myeloid/lymphoid or mixed-lineage leukemia (MLL) family and encodes a protein with an N-terminal PHD zinc finger and a central SET domain. Overexpression of the protein inhibits cell cycle progression. Alternate transcriptional splice variants have been characterized.
Genomic Location
Associated SNPs
| SNP | Genotype | Ref. Allele | Variant Allele | Frequency | Status |
|---|---|---|---|---|---|
| rs111931861 | -- | A | G | 3.40% | No Data |
MACROD2 GeneCards
The protein encoded by this gene is a deacetylase involved in removing ADP-ribose from mono-ADP-ribosylated proteins. The encoded protein has been shown to translocate from the nucleus to the cytoplasm upon DNA damage.
Genomic Location
Associated SNPs
| SNP | Genotype | Ref. Allele | Variant Allele | Frequency | Status |
|---|---|---|---|---|---|
| rs71190156 | -- | G | G | 51.90% | No Data |
MROH5 GeneCards
Genomic Location
Associated SNPs
| SNP | Genotype | Ref. Allele | Variant Allele | Frequency | Status |
|---|---|---|---|---|---|
| rs11787216 | -- | C | T | 63.60% | No Data |
NKX2-2 GeneCards
Genomic Location
No SNPs found for this gene in your DNA data.
NKX2-4 GeneCards
NK2 homeobox 4
Genomic Location
No SNPs found for this gene in your DNA data.
PINX1 GeneCards
PIN2 (TERF1) interacting telomerase inhibitor 1
Genomic Location
No SNPs found for this gene in your DNA data.
PTBP2 GeneCards
polypyrimidine tract binding protein 2
Genomic Location
No SNPs found for this gene in your DNA data.
SOX7 GeneCards
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may play a role in tumorigenesis. A similar protein in mice is involved in the regulation of the wingless-type MMTV integration site family (Wnt) pathway.
Genomic Location
No SNPs found for this gene in your DNA data.
SRPK2 GeneCards
SRSF protein kinase 2
Genomic Location
No SNPs found for this gene in your DNA data.
XRN2 GeneCards
5'-3' exoribonuclease 2
Genomic Location
No SNPs found for this gene in your DNA data.
These are the genetic markers (SNPs) analyzed for this trait. Variations detected in your genome are listed under the "Genotype" column. SNPs showing "--" were not identified in your DNA file.
| SNP | Chromosome | Genotype | Variant Allele | Frequency |
|---|---|---|---|---|
| rs6692705 | 1 | GG | G | 40.00% |
| rs2391769 | 1 | AG | G | 63.10% |
| rs1452075 | 3 | TT | T | 72.10% |
| rs4916723 | 5 | AC | C | 42.80% |
| rs325485 | 5 | GG | G | 37.80% |
| rs6701243 | 1 | -- | C | 60.90% |
| rs11185408 | 1 | -- | A | 47.70% |
| rs201910565 | 1 | -- | A | 31.10% |
| chr11:102751102 | -- | ? | 3.70% | |
| chr5:168173526 | -- | A | 1.60% | |
| chr7:105064665 | -- | T | 25.00% | |
| chr6:96509180 | -- | D | 64.10% | |
| rs59566011 | 2 | -- | G | 56.90% |
| rs79940520 | 3 | -- | G | 14.10% |
| rs148587110 | 3 | -- | C | 1.10% |
| rs200332011 | 3 | -- | C | 76.90% |
| rs56054767 | 4 | -- | C | 11.30% |
| rs2635182 | 5 | -- | T | 46.60% |
| rs13188074 | 5 | -- | G | 39.10% |
| rs34509057 | 5 | -- | A | 22.60% |
| rs34739626 | 6 | -- | T | 61.70% |
| rs12203328 | 6 | -- | C | 27.80% |
| rs210894 | 6 | -- | T | 54.80% |
| rs72934503 | 6 | -- | G | 46.30% |
| rs740883 | 6 | -- | T | 8.80% |
| rs111931861 | 7 | -- | G | 3.40% |
| rs10099100 | 8 | -- | C | 33.10% |
| rs10110094 | 8 | -- | G | 16.30% |
| rs183563276 | 8 | -- | C | 1.10% |
| rs11787216 | 8 | -- | T | 63.60% |
| rs113764414 | 10 | -- | G | 67.20% |
| rs45595836 | 10 | -- | T | 6.70% |
| rs141319505 | 10 | -- | G | 98.00% |
| rs117603308 | 11 | -- | G | 2.60% |
| rs77691144 | 13 | -- | C | 2.50% |
| rs201369005 | 14 | -- | G | 5.10% |
| rs112635299 | 14 | -- | T | 2.50% |
| rs141455452 | 17 | -- | G | 52.50% |
| rs12942300 | 17 | -- | A | 82.90% |
| rs142920272 | 17 | -- | C | 18.70% |
| rs143609523 | 18 | -- | G | 1.20% |
| rs292441 | 18 | -- | A | 32.40% |
| rs138867053 | 19 | -- | A | 1.70% |
| rs71190156 | 20 | -- | G | 51.90% |
| rs6047270 | 20 | -- | C | 31.90% |
| rs910805 | 20 | -- | A | 24.00% |
The following peer-reviewed scientific studies support the genetic associations analyzed in this report.
What's Next?
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