Genetic Predisposition
Based on your genetic markers, your predisposition to this trait is shown below
Your Result
Higher Household income capacity predisposition
Was this result accurate for you?
Scientific Evidence
Understanding the Data
- SNP: A specific genetic marker relevant to this trait (e.g., rs2588978)
- Genotype: Your genetic makeup at the given SNP location (e.g., CC)
- Variant allele: The alternative DNA sequence at the SNP site
- Variant allele frequency: Percentage of population carrying this variant
- Variant found: Whether the variant was detected in your DNA file
FARP1 GeneCards
FERM, ARH/RhoGEF and pleckstrin domain protein 1
Genomic Location
Associated SNPs
ZSWIM6 GeneCards
The protein encoded by this gene contains a zinc finger SWI2/SNF2 and MuDR (SWIM) domain. Proteins with SWIM domains have been found in a diverse number of species and are predicted to interact with DNA or proteins. Mutations in this gene result in acromelic frontonasal dysostosis.
Genomic Location
Associated SNPs
AC012493.1 GeneCards
Genomic Location
Associated SNPs
| SNP | Genotype | Ref. Allele | Variant Allele | Frequency | Status |
|---|---|---|---|---|---|
| rs56211325 | -- | C | T | 0.50% | No Data |
AC012493.1 GeneCards
Genomic Location
Associated SNPs
| SNP | Genotype | Ref. Allele | Variant Allele | Frequency | Status |
|---|---|---|---|---|---|
| rs56211325 | -- | C | T | 0.50% | No Data |
ADD1 GeneCards
Adducins are a family of cytoskeletal proteins encoded by three genes (alpha, beta, and gamma). Adducin acts as a heterodimer of the related alpha, beta, or gamma subunits. The protein encoded by this gene represents the alpha subunit. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C.
Genomic Location
Associated SNPs
| SNP | Genotype | Ref. Allele | Variant Allele | Frequency | Status |
|---|---|---|---|---|---|
| rs12647647 | -- | T | A | 15.34% | No Data |
ARAP3 GeneCards
This gene encodes a phosphoinositide binding protein containing ARF-GAP, RHO-GAP, RAS-associating, and pleckstrin homology domains. The ARF-GAP and RHO-GAP domains cooperate in mediating rearrangements in the cell cytoskeleton and cell shape. It is a specific PtdIns(3,4,5)P3/PtdIns(3,4)P2-stimulated Arf6-GAP protein. An alternatively spliced transcript has been found for this gene, but its biological validity has not been determined.
Genomic Location
Associated SNPs
| SNP | Genotype | Ref. Allele | Variant Allele | Frequency | Status |
|---|---|---|---|---|---|
| rs32940 | -- | T | C | 73.42% | No Data |
CASC3 GeneCards
Genomic Location
Associated SNPs
| SNP | Genotype | Ref. Allele | Variant Allele | Frequency | Status |
|---|---|---|---|---|---|
| rs151114485 | -- | G | A | 1.18% | No Data |
CELF4 GeneCards
CUGBP Elav-like family member 4
Genomic Location
Associated SNPs
| SNP | Genotype | Ref. Allele | Variant Allele | Frequency | Status |
|---|---|---|---|---|---|
| rs4799936 | -- | G | A | 45.11% | No Data |
| rs12967855 | -- | A | G | 46.94% | No Data |
ELOVL7 GeneCards
Genomic Location
Associated SNPs
| SNP | Genotype | Ref. Allele | Variant Allele | Frequency | Status |
|---|---|---|---|---|---|
| rs13158665 | -- | C | T | 32.05% | No Data |
| rs57468227 | -- | T | C | 26.50% | No Data |
ERBB4 GeneCards
This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described
Genomic Location
Associated SNPs
| SNP | Genotype | Ref. Allele | Variant Allele | Frequency | Status |
|---|---|---|---|---|---|
| rs62183028 | -- | G | T | 19.33% | No Data |
| rs7597007 | -- | G | T | 70.99% | No Data |
| rs59779307 | -- | T | C | 36.00% | No Data |
| rs11693031 | -- | A | G | 28.19% | No Data |
FASTKD5 GeneCards
Genomic Location
No SNPs found for this gene in your DNA data.
GIP GeneCards
Genomic Location
Associated SNPs
| SNP | Genotype | Ref. Allele | Variant Allele | Frequency | Status |
|---|---|---|---|---|---|
| rs146301099 | -- | G | T | 40.10% | No Data |
GLCCI1 GeneCards
This gene encodes a protein of unknown function. Expression of this gene is induced by glucocorticoids and may be an early marker for glucocorticoid-induced apoptosis. Single nucleotide polymorphisms in this gene are associated with a decreased response to inhaled glucocorticoids in asthmatic patients.
Genomic Location
No SNPs found for this gene in your DNA data.
KANSL1 GeneCards
This gene encodes a nuclear protein that is a subunit of two protein complexes involved with histone acetylation, the MLL1 complex and the NSL1 complex. The corresponding protein in Drosophila interacts with K(lysine) acetyltransferase 8, which is also a subunit of both the MLL1 and NSL1 complexes.
Genomic Location
Associated SNPs
KMT2E GeneCards
This gene is a member of the myeloid/lymphoid or mixed-lineage leukemia (MLL) family and encodes a protein with an N-terminal PHD zinc finger and a central SET domain. Overexpression of the protein inhibits cell cycle progression. Alternate transcriptional splice variants have been characterized.
Genomic Location
Associated SNPs
| SNP | Genotype | Ref. Allele | Variant Allele | Frequency | Status |
|---|---|---|---|---|---|
| rs4727618 | -- | G | A | 66.85% | No Data |
LINC01104 GeneCards
Genomic Location
Associated SNPs
| SNP | Genotype | Ref. Allele | Variant Allele | Frequency | Status |
|---|---|---|---|---|---|
| rs13002946 | -- | T | A | 30.65% | No Data |
| rs12614880 | -- | A | G | 26.14% | No Data |
| rs4443016 | -- | C | G | 48.20% | No Data |
| rs9653442 | -- | C | T | 43.11% | No Data |
| rs10167279 | -- | T | A | 50.02% | No Data |
LONRF2 GeneCards
LON peptidase N-terminal domain and ring finger 2
Genomic Location
Associated SNPs
| SNP | Genotype | Ref. Allele | Variant Allele | Frequency | Status |
|---|---|---|---|---|---|
| rs11123825 | -- | G | A | 71.39% | No Data |
| rs11895772 | -- | G | C | 40.38% | No Data |
LRRN2 GeneCards
leucine rich repeat neuronal 2
Genomic Location
Associated SNPs
| SNP | Genotype | Ref. Allele | Variant Allele | Frequency | Status |
|---|---|---|---|---|---|
| rs11588857 | -- | G | A | 18.43% | No Data |
LYL1 GeneCards
Genomic Location
Associated SNPs
| SNP | Genotype | Ref. Allele | Variant Allele | Frequency | Status |
|---|---|---|---|---|---|
| rs12151248 | -- | C | T | 5.05% | No Data |
MAPT GeneCards
This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.
Genomic Location
Associated SNPs
| SNP | Genotype | Ref. Allele | Variant Allele | Frequency | Status |
|---|---|---|---|---|---|
| rs62056789 | -- | A | C | 8.61% | No Data |
| rs17652520 | -- | G | A | 8.91% | No Data |
MARCKS GeneCards
myristoylated alanine rich protein kinase C substrate
Genomic Location
Associated SNPs
| SNP | Genotype | Ref. Allele | Variant Allele | Frequency | Status |
|---|---|---|---|---|---|
| rs28558559 | -- | T | C | 13.22% | No Data |
NDUFA2 GeneCards
The encoded protein is a subunit of the hydrophobic protein fraction of the NADH:ubiquinone oxidoreductase (complex 1), the first enzyme complex in the electron transport chain located in the inner mitochondrial membrane, and may be involved in regulating complex I activity or its assembly via assistance in redox processes. Mutations in this gene are associated with Leigh syndrome, an early-onset progressive neurodegenerative disorder. Alternative splicing results in multiple transcript variants.
Genomic Location
Associated SNPs
| SNP | Genotype | Ref. Allele | Variant Allele | Frequency | Status |
|---|---|---|---|---|---|
| rs2563332 | -- | C | T | 18.45% | No Data |
NDUFAF2 GeneCards
NADH:ubiquinone oxidoreductase (complex I) catalyzes the transfer of electrons from NADH to ubiquinone (coenzyme Q) in the first step of the mitochondrial respiratory chain, resulting in the translocation of protons across the inner mitochondrial membrane. This gene encodes a complex I assembly factor. Mutations in this gene cause progressive encephalopathy resulting from mitochondrial complex I deficiency.
Genomic Location
Associated SNPs
| SNP | Genotype | Ref. Allele | Variant Allele | Frequency | Status |
|---|---|---|---|---|---|
| rs248686 | -- | C | T | 86.96% | No Data |
RN7SL205P GeneCards
Genomic Location
Associated SNPs
| SNP | Genotype | Ref. Allele | Variant Allele | Frequency | Status |
|---|---|---|---|---|---|
| rs28896784 | -- | T | G | 68.09% | No Data |
RNF123 GeneCards
The protein encoded by this gene contains a C-terminal RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions, and an N-terminal SPRY domain. This protein displays E3 ubiquitin ligase activity toward the cyclin-dependent kinase inhibitor 1B which is also known as p27 or KIP1. Alternative splicing results in multiple transcript variants.
Genomic Location
Associated SNPs
| SNP | Genotype | Ref. Allele | Variant Allele | Frequency | Status |
|---|---|---|---|---|---|
| rs73077157 | -- | A | C | 6.47% | No Data |
ST3GAL3 GeneCards
The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi apparatus but can be proteolytically processed to a soluble form. This protein is a member of glycosyltransferase family 29. Mutations in this gene have been associated with a form of autosomal recessive nonsymdromic cognitive disability as well as infantile epileptic encephalopathy. Multiple transcript variants encoding several different isoforms have been found for this gene.
Genomic Location
Associated SNPs
| SNP | Genotype | Ref. Allele | Variant Allele | Frequency | Status |
|---|---|---|---|---|---|
| rs12119149 | -- | C | T | 63.62% | No Data |
SUMO2P2 GeneCards
Genomic Location
Associated SNPs
| SNP | Genotype | Ref. Allele | Variant Allele | Frequency | Status |
|---|---|---|---|---|---|
| rs10733389 | -- | A | G | 52.92% | No Data |
| rs4557790 | -- | C | A | 63.02% | No Data |
| rs2094889 | -- | T | C | 32.13% | No Data |
| rs10429582 | -- | T | C | 33.19% | No Data |
UBOX5 GeneCards
Genomic Location
No SNPs found for this gene in your DNA data.
These are the genetic markers (SNPs) analyzed for this trait. Variations detected in your genome are listed under the "Genotype" column. SNPs showing "--" were not identified in your DNA file.
| SNP | Chromosome | Genotype | Variant Allele | Frequency |
|---|---|---|---|---|
| rs6699397 | 1 | AG | G | 34.50% |
| rs2280406 | 3 | GA | A | 36.30% |
| rs2332719 | 3 | AG | G | 50.02% |
| rs9822268 | 3 | GA | A | 20.89% |
| rs36198109 | 5 | AA | A | 28.93% |
| rs4490539 | 5 | AG | G | 23.30% |
| rs10872224 | 6 | GT | T | 68.91% |
| rs37976 | 7 | CT | T | 59.68% |
| rs9517310 | 13 | CT | T | 18.41% |
| rs11588857 | 1 | -- | A | 18.43% |
| rs12119149 | 1 | -- | T | 63.62% |
| rs62183028 | 2 | -- | T | 19.33% |
| rs139897186 | 2 | -- | G | 1.04% |
| rs7597007 | 2 | -- | T | 70.99% |
| rs11123825 | 2 | -- | A | 71.39% |
| rs13002946 | 2 | -- | A | 30.65% |
| rs59779307 | 2 | -- | C | 36.00% |
| rs12614880 | 2 | -- | G | 26.14% |
| rs1455350 | 2 | -- | A | 55.37% |
| rs4443016 | 2 | -- | G | 48.20% |
| rs11693031 | 2 | -- | G | 28.19% |
| rs9653442 | 2 | -- | T | 43.11% |
| rs10167279 | 2 | -- | A | 50.02% |
| rs56211325 | 2 | -- | T | 0.50% |
| rs11895772 | 2 | -- | C | 40.38% |
| rs73077157 | 3 | -- | C | 6.47% |
| rs12647647 | 4 | -- | A | 15.34% |
| rs28896784 | 4 | -- | G | 68.09% |
| rs11943536 | 4 | -- | T | 20.13% |
| rs13158665 | 5 | -- | T | 32.05% |
| rs57468227 | 5 | -- | C | 26.50% |
| rs248686 | 5 | -- | T | 86.96% |
| rs62366190 | 5 | -- | G | 23.16% |
| rs7719676 | 5 | -- | G | 87.86% |
| rs2563332 | 5 | -- | T | 18.45% |
| rs32940 | 5 | -- | C | 73.42% |
| rs159368 | 5 | -- | G | 83.33% |
| rs159365 | 5 | -- | G | 71.94% |
| rs4583848 | 5 | -- | C | 54.87% |
| rs28558559 | 6 | -- | C | 13.22% |
| rs1933720 | 6 | -- | C | 21.07% |
| rs1906252 | 6 | -- | A | 33.61% |
| rs2388148 | 6 | -- | T | 25.16% |
| rs6931604 | 6 | -- | T | 47.58% |
| rs2503776 | 6 | -- | T | 50.38% |
| rs4587178 | 6 | -- | C | 46.09% |
| rs6933464 | 6 | -- | T | 26.40% |
| rs1338549 | 6 | -- | G | 66.49% |
| rs4727618 | 7 | -- | A | 66.85% |
| rs6477496 | 9 | -- | T | 17.81% |
| rs10733389 | 9 | -- | G | 52.92% |
| rs4557790 | 9 | -- | A | 63.02% |
| rs2094889 | 9 | -- | C | 32.13% |
| rs10429582 | 9 | -- | C | 33.19% |
| rs9556958 | 13 | -- | T | 40.58% |
| rs146301099 | 17 | -- | T | 40.10% |
| rs62056789 | 17 | -- | C | 8.61% |
| rs151114485 | 17 | -- | A | 1.18% |
| rs974295 | 17 | -- | T | 8.63% |
| rs2732596 | 17 | -- | T | 0.00% |
| rs17652520 | 17 | -- | A | 8.91% |
| rs4799936 | 18 | -- | A | 45.11% |
| rs784256 | 18 | -- | A | 89.64% |
| rs12967855 | 18 | -- | G | 46.94% |
| rs12954483 | 18 | -- | G | 89.40% |
| rs12151248 | 19 | -- | T | 5.05% |
| rs2255158 | 20 | -- | G | 85.20% |
| rs306755 | 20 | -- | C | 39.62% |
The following peer-reviewed scientific studies support the genetic associations analyzed in this report.
What's Next?
Print Report
Download or print this report for your records