Bone strength

Bone strength here refers to research on inherited differences in fracture susceptibility, including stress fractures from repeated load.

GWAS work has identified variants linked to bone density, bone geometry, and collagen biology that affect fracture risk.

This result reflects research-level variation in bone biology and is not a clinical fracture-risk assessment.

Training load, calcium and vitamin D, hormones, body weight, footwear, surface, and recovery also strongly influence actual stress-fracture risk.

0 SNPs

1 Study

Jun 02, 2026

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Scientific Evidence

The following peer-reviewed scientific studies support the genetic associations analyzed in this report.

An atlas of genetic influences on osteoporosis in humans and mice

Evidence

2019 Feb

Nat Genet

Authors: Morris JA, Kemp JP, Youlten SE, Laurent L, Logan JG, Chai RC, Vulpescu NA, Forgetta V, Kleinman A, Mohanty ST, Sergio CM, Quinn J, Nguyen-Yamamoto L, Luco AL, Vijay J, Simon MM, Pramatarova A, Medina-Gomez C, Trajanoska K, Ghirardello EJ, Butterfield NC, Curry KF, Leitch VD, Sparkes PC, Adoum AT, Mannan NS, Komla-Ebri DSK, Pollard AS, Dewhurst HF, Hassall TAD, Beltejar MG, , Adams DJ, Vaillancourt SM, Kaptoge S, Baldock P, Cooper C, Reeve J, Ntzani EE, Evangelou E, Ohlsson C, Karasik D, Rivadeneira F, Kiel DP, Tobias JH, Gregson CL, Harvey NC, Grundberg E, Goltzman D, Adams DJ, Lelliott CJ, Hinds DA, Ackert-Bicknell CL, Hsu YH, Maurano MT, Croucher PI, Williams GR, Bassett JHD, Evans DM, Richards JB

426,824 individuals (european ancestry)

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Important Medical Disclaimer

This report is intended for educational and informational purposes only. It is not intended to provide medical advice or be used solely by the customer in the diagnosis, cure, mitigation, treatment, or prevention of any disease or health condition. If you have serious medical conditions, including but not limited to weight-related issues, diabetes, or heart disease, you should not make changes to your diet or exercise routine without consulting your healthcare provider. Under no circumstances should you modify your medication or medical care without professional medical guidance.

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