Active: Age-related macular degeneration Clear all

GWAS 2025-12-08

HTRA1/lncRNA HTRA1-AS1 dominates in age-related macular degeneration reticular pseudodrusen genetic risk with no complement involvement.

Farashi S

Nat Commun

Age-related macular degeneration with reticular pseudodrusen

9232

Participants

N/A

Studies

Details PubMed

GWAS 2025-02-04

Multi-omic spatial effects on high-resolution AI-derived retinal thickness.

Jackson VE, Wu Y et al.

Nat Commun

Retinal thickness is a marker of retinal health and more broadly, is seen as a promising biomarker f...

Retinal thickness (functional principal component 1)

Replicated

45488

Participants

N/A

Studies

Details PubMed

GWAS 2024-06-06

Genome wide association study and genomic risk prediction of age related macular degeneration in Israel.

Grunin M, Triffon D et al.

Sci Rep

The risk of developing age-related macular degeneration (AMD) is influenced by genetic background. I...

Age-related macular degeneration

Replicated

883

Participants

N/A

Studies

Details PubMed

GWAS 2024-03-12

Identification of Genetic Variants for Risk Prediction and Early Diagnosis of Age-Related Macular Degeneration in the Taiwanese Population.

Huang YC, Liao WL et al.

Int J Mol Sci

Age-related macular degeneration (AMD) is the leading cause of blindness in the elderly worldwide. T...

Age-related macular degeneration

14343

Participants

N/A

Studies

Details PubMed

GWAS 2023-11-06

Genome-Wide Association Study of Cardiovascular Resilience Identifies Protective Variation in the CETP Gene.

Yu C, Bakshi A et al.

J Am Heart Assoc

Background The risk of atherosclerotic cardiovascular disease (ASCVD) increases sharply with age. So...

ASCVD risk score (Systematic Coronary Risk Evaluation 2-Older People-Lipid scores)

Replicated

25919

Participants

N/A

Studies

Details PubMed

GWAS 2023-11-02

Whole genome sequencing of 4,787 individuals identifies gene-based rare variants in age-related macular degeneration.

Kwong A, Zawistowski M et al.

Hum Mol Genet

Genome-wide association studies have contributed extensively to the discovery of disease-associated ...

Age-related macular degeneration

4787

Participants

N/A

Studies

Details PubMed

GWAS 2023-11-01

Whole Genome Sequencing Identifies Novel Common and Low-Frequency Variants Associated With Age-Related Macular Degeneration.

Acar IE, Galesloot TE et al.

Invest Ophthalmol Vis Sci

Purpose: To identify associations of common, low-frequency, and rare variants with advanced age-rela...

Age-related macular degeneration

4827

Participants

N/A

Studies

Details PubMed

GWAS 2023-09-11

Contribution of common and rare variants to Asian neovascular age-related macular degeneration subtypes.

Fan Q, Li H et al.

Nat Commun

Neovascular age-related macular degeneration (nAMD), along with its clinical subtype known as polypo...

Neovascular age-related macular degeneration

8621

Participants

N/A

Studies

Details PubMed

GWAS 2023-06-09

Identifying missing pieces in color vision defects: a genome-wide association study in Silk Road populations.

Nardone GG, Spedicati B et al.

Front Genet

Introduction: Color vision defects (CVDs) are conditions characterized by the alteration of normal t...

Color vision defects (Deutan-Protan)

514

Participants

N/A

Studies

Details PubMed

GWAS 2023-03-14

Genome-wide analysis of genetic pleiotropy and causal genes across three age-related ocular disorders.

Yao X, Yang H et al.

Hum Genet

Age-related macular degeneration (AMD), cataract, and glaucoma are leading causes of blindness world...

AMD or cataract or glaucoma (pleiotropy)

818138

Participants

N/A

Studies

Details PubMed

GWAS 2023-02-24

Genome-wide association study and identification of systemic comorbidities in development of age-related macular degeneration in a hospital-based cohort of Han Chinese.

Shih CH, Chuang HK et al.

Front Genet

Age-related macular degeneration (AMD) is the main cause of severe vision loss in elderly population...

Age-related macular degeneration

3729

Participants

N/A

Studies

Details PubMed

GWAS 2022-12-23

Genome-Wide Pleiotropy Study Identifies Association of PDGFB with Age-Related Macular Degeneration and COVID-19 Infection Outcomes.

Chung J, Vig V et al.

J Clin Med

Age-related macular degeneration (AMD) has been implicated as a risk factor for severe consequences ...

Age-related macular degeneration or COVID-19 critical illness (MTAG)

1422309

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

HTRA1/lncRNA HTRA1-AS1 dominates in age-related macular degeneration reticular pseudodrusen genetic risk with no complement involvement.

Farashi S

Nat Commun

Age-related macular degeneration with reticular pseudodrusen

2025-12-08

Multi-omic spatial effects on high-resolution AI-derived retinal thickness.

Jackson VE, Wu Y et al.

Nat Commun

Retinal thickness (functional principal component 1)

2025-02-04

Genome wide association study and genomic risk prediction of age related macular degeneration in Israel.

Grunin M, Triffon D et al.

Sci Rep

Age-related macular degeneration

2024-06-06

Identification of Genetic Variants for Risk Prediction and Early Diagnosis of Age-Related Macular Degeneration in the Taiwanese Population.

Huang YC, Liao WL et al.

Int J Mol Sci

Age-related macular degeneration

2024-03-12

Genome-Wide Association Study of Cardiovascular Resilience Identifies Protective Variation in the CETP Gene.

Yu C, Bakshi A et al.

J Am Heart Assoc

ASCVD risk score (Systematic Coronary Risk Evaluation 2-Older People-Lipid scores)

2023-11-06

Whole genome sequencing of 4,787 individuals identifies gene-based rare variants in age-related macular degeneration.

Kwong A, Zawistowski M et al.

Hum Mol Genet

Age-related macular degeneration

2023-11-02

Whole Genome Sequencing Identifies Novel Common and Low-Frequency Variants Associated With Age-Related Macular Degeneration.

Acar IE, Galesloot TE et al.

Invest Ophthalmol Vis Sci

Age-related macular degeneration

2023-11-01

Contribution of common and rare variants to Asian neovascular age-related macular degeneration subtypes.

Fan Q, Li H et al.

Nat Commun

Neovascular age-related macular degeneration

2023-09-11

Identifying missing pieces in color vision defects: a genome-wide association study in Silk Road populations.

Nardone GG, Spedicati B et al.

Front Genet

Color vision defects (Deutan-Protan)

2023-06-09

Genome-wide analysis of genetic pleiotropy and causal genes across three age-related ocular disorders.

Yao X, Yang H et al.

Hum Genet

AMD or cataract or glaucoma (pleiotropy)

2023-03-14

Genome-wide association study and identification of systemic comorbidities in development of age-related macular degeneration in a hospital-based cohort of Han Chinese.

Shih CH, Chuang HK et al.

Front Genet

Age-related macular degeneration

2023-02-24

Genome-Wide Pleiotropy Study Identifies Association of PDGFB with Age-Related Macular Degeneration and COVID-19 Infection Outcomes.

Chung J, Vig V et al.

J Clin Med

Age-related macular degeneration or COVID-19 critical illness (MTAG)

2022-12-23

Health & Traits Publications

HTRA1/lncRNA HTRA1-AS1 dominates in age-related macular degeneration reticular pseudodrusen genetic risk with no complement involvement.

Multi-omic spatial effects on high-resolution AI-derived retinal thickness.

Genome wide association study and genomic risk prediction of age related macular degeneration in Israel.

Identification of Genetic Variants for Risk Prediction and Early Diagnosis of Age-Related Macular Degeneration in the Taiwanese Population.

Genome-Wide Association Study of Cardiovascular Resilience Identifies Protective Variation in the <i>CETP</i> Gene.

Whole genome sequencing of 4,787 individuals identifies gene-based rare variants in age-related macular degeneration.

Whole Genome Sequencing Identifies Novel Common and Low-Frequency Variants Associated With Age-Related Macular Degeneration.

Contribution of common and rare variants to Asian neovascular age-related macular degeneration subtypes.

Identifying missing pieces in color vision defects: a genome-wide association study in Silk Road populations.

Genome-wide analysis of genetic pleiotropy and causal genes across three age-related ocular disorders.

Genome-wide association study and identification of systemic comorbidities in development of age-related macular degeneration in a hospital-based cohort of Han Chinese.

Genome-Wide Pleiotropy Study Identifies Association of <i>PDGFB</i> with Age-Related Macular Degeneration and COVID-19 Infection Outcomes.