Active: Aggressive periodontitis Clear all

GWAS 2023-12-23

A genome-wide association study meta-analysis in a European sample of stage III/IV grade C periodontitis patients ≤35 years of age identifies new risk loci.

De Almeida SD, Richter GM et al.

J Clin Periodontol

Aim: Few genome-wide association studies (GWAS) have been conducted for severe forms of periodontiti...

Aggressive periodontitis

9123

Participants

N/A

Studies

Details PubMed

GWAS 2018-09-14

Meta-analysis of genome-wide association studies of aggressive and chronic periodontitis identifies two novel risk loci.

Munz M, Richter GM et al.

Eur J Hum Genet

Periodontitis is one of the most common inflammatory diseases, with a prevalence of 11% worldwide fo...

Periodontitis

Replicated

15003

Participants

N/A

Studies

Details PubMed

GWAS 2018-09-11

GWAS for Interleukin-1β levels in gingival crevicular fluid identifies IL37 variants in periodontal inflammation.

Offenbacher S, Jiao Y et al.

Nat Commun

There is no agnostic GWAS evidence for the genetic control of IL-1β expression in periodontal diseas...

High IL-1beta levels in gingival crevicular fluid

4910

Participants

N/A

Studies

Details PubMed

GWAS 2017-04-25

A genome-wide association study identifies nucleotide variants at SIGLEC5 and DEFA1A3 as risk loci for periodontitis.

Munz M, Willenborg C et al.

Hum Mol Genet

Periodontitis is one of the most common inflammatory diseases, with a prevalence of 11% worldwide fo...

Aggressive periodontitis

Replicated

8474

Participants

N/A

Studies

Details PubMed

GWAS 2016-03-08

Genome-wide association study of biologically informed periodontal complex traits offers novel insights into the genetic basis of periodontal disease.

Offenbacher S, Divaris K et al.

Hum Mol Genet

Genome-wide association studies (GWAS) of chronic periodontitis (CP) defined by clinical criteria al...

Periodontal disease-related phenotype (Socransky)

975

Participants

N/A

Studies

Details PubMed

GWAS 2014-09-25

Genome-wide exploration identifies sex-specific genetic effects of alleles upstream NPY to increase the risk of severe periodontitis in men.

Freitag-Wolf S, Dommisch H et al.

J Clin Periodontol

Aim: Periodontitis (PD) is influenced by genetic as well as lifestyle and socio-economic factors. Ep...

Aggressive periodontitis (sex interaction)

Replicated

2183

Participants

N/A

Studies

Details PubMed

GWAS 2009-11-06

A genome-wide association study identifies GLT6D1 as a susceptibility locus for periodontitis.

Schaefer AS, Richter GM et al.

Hum Mol Genet

Periodontitis is a widespread, complex inflammatory disease of the mouth, which results in a loss of...

Periodontitis

Replicated

1751

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

A genome-wide association study meta-analysis in a European sample of stage III/IV grade C periodontitis patients ≤35 years of age identifies new risk loci.

De Almeida SD, Richter GM et al.

J Clin Periodontol

Aggressive periodontitis

2023-12-23

Meta-analysis of genome-wide association studies of aggressive and chronic periodontitis identifies two novel risk loci.

Munz M, Richter GM et al.

Eur J Hum Genet

Periodontitis

2018-09-14

GWAS for Interleukin-1β levels in gingival crevicular fluid identifies IL37 variants in periodontal inflammation.

Offenbacher S, Jiao Y et al.

Nat Commun

High IL-1beta levels in gingival crevicular fluid

2018-09-11

A genome-wide association study identifies nucleotide variants at SIGLEC5 and DEFA1A3 as risk loci for periodontitis.

Munz M, Willenborg C et al.

Hum Mol Genet

Aggressive periodontitis

2017-04-25

Genome-wide association study of biologically informed periodontal complex traits offers novel insights into the genetic basis of periodontal disease.

Offenbacher S, Divaris K et al.

Hum Mol Genet

Periodontal disease-related phenotype (Socransky)

2016-03-08

Genome-wide exploration identifies sex-specific genetic effects of alleles upstream NPY to increase the risk of severe periodontitis in men.

Freitag-Wolf S, Dommisch H et al.

J Clin Periodontol

Aggressive periodontitis (sex interaction)

2014-09-25

A genome-wide association study identifies GLT6D1 as a susceptibility locus for periodontitis.

Schaefer AS, Richter GM et al.

Hum Mol Genet

Periodontitis

2009-11-06