Active: Alanine aminotransferase levels Clear all

GWAS 2022-05-28

Genetics are not likely to offer clinically useful predictions for elevated liver enzyme levels in patients using low dose methotrexate.

Cui J, Chasman DI et al.

Semin Arthritis Rheum

Objective: To examine genetic influence on the risk of elevations in liver function tests (AST and A...

Alanine aminotransferase levels in low dose methotrexate treatment

1429

Participants

N/A

Studies

Details PubMed

GWAS 2021-06-29

Genome-wide association analysis of serum alanine and aspartate aminotransferase, and the modifying effects of BMI in 388k European individuals.

Gao C, Marcketta A et al.

Genet Epidemiol

Serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) are biomarkers for liver h...

Alanine aminotransferase levels

388865

Participants

N/A

Studies

Details PubMed

GWAS 2021-02-05

Genome-wide association study of serum liver enzymes implicates diverse metabolic and liver pathology.

Chen VL, Du X et al.

Nat Commun

Serum liver enzyme concentrations are the most frequently-used laboratory markers of liver disease, ...

Alanine aminotransferase levels

Replicated

524966

Participants

N/A

Studies

Details PubMed

GWAS 2019-06-20

Genome-Wide Association Study Identifies Loci for Liver Enzyme Concentrations in Mexican Americans: The GUARDIAN Consortium.

Young KA, Palmer ND et al.

Obesity (Silver Spring)

Objective: Populations of Mexican American ancestry are at an increased risk for nonalcoholic fatty ...

Alanine aminotransferase levels

3595

Participants

N/A

Studies

Details PubMed

GWAS 2007-05-15

Genome-wide pharmacogenetic investigation of a hepatic adverse event without clinical signs of immunopathology suggests an underlying immune pathogenesis.

Kindmark A, Jawaid A et al.

Pharmacogenomics J

One of the major goals of pharmacogenetics is to elucidate mechanisms and identify patients at incre...

Response to ximelagatran treatment (increased serum alanine aminotransferase levels)

Replicated

230

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Genetics are not likely to offer clinically useful predictions for elevated liver enzyme levels in patients using low dose methotrexate.

Cui J, Chasman DI et al.

Semin Arthritis Rheum

Alanine aminotransferase levels in low dose methotrexate treatment

2022-05-28

Genome-wide association analysis of serum alanine and aspartate aminotransferase, and the modifying effects of BMI in 388k European individuals.

Gao C, Marcketta A et al.

Genet Epidemiol

Alanine aminotransferase levels

2021-06-29

Genome-wide association study of serum liver enzymes implicates diverse metabolic and liver pathology.

Chen VL, Du X et al.

Nat Commun

Alanine aminotransferase levels

2021-02-05

Genome-Wide Association Study Identifies Loci for Liver Enzyme Concentrations in Mexican Americans: The GUARDIAN Consortium.

Young KA, Palmer ND et al.

Obesity (Silver Spring)

Alanine aminotransferase levels

2019-06-20

Genome-wide pharmacogenetic investigation of a hepatic adverse event without clinical signs of immunopathology suggests an underlying immune pathogenesis.

Kindmark A, Jawaid A et al.

Pharmacogenomics J

Response to ximelagatran treatment (increased serum alanine aminotransferase levels)

2007-05-15