Active: Alzheimer's disease Clear all

GWAS 2026-02-01

Ethnic-specific effects of the LILRB2-LILRB5 locus and newly identified risk loci for Alzheimer's disease in the East Asian population.

Cao H

Alzheimers Dement

Alzheimer's disease

2116

Participants

N/A

Studies

Details PubMed

GWAS 2026-02-01

Matching heterogeneous cohorts by projected principal components reveals two novel Alzheimer's disease-associated genes in the Hispanic population.

Willett JDS

Alzheimers Dement

Alzheimer's disease

8467

Participants

N/A

Studies

Details PubMed

GWAS 2025-12-05

No causal links between estradiol and female's brain and mental health using Mendelian randomization.

Oppenheimer H, van der Meer D et al.

Nat Commun

The role of estradiol in depression and Alzheimer's disease - brain disorders that disproportionatel...

Brain age gap

13423

Participants

N/A

Studies

Details PubMed

GWAS 2025-11-01

Alzheimer's disease multi-ancestry genome-wide interaction and stratified study with smoking.

Dacey R

Alzheimers Dement

Alzheimer's disease in non-smokers

1650

Participants

N/A

Studies

Details PubMed

GWAS 2025-10-09

Genome-wide association study provides insights into the genetic basis of Lewy body dementia.

Zhu P, Jin Z et al.

Mol Psychiatry

Lewy body dementia (LBD) is the second most prevalent dementia, however most genetic risk remains un...

Dementia with Lewy bodies

Replicated

193542

Participants

N/A

Studies

Details PubMed

GWAS 2025-09-01

Multi-ancestry meta-analysis identifies genetic modifiers of age-at-onset of Alzheimer's disease at known and novel loci.

Blue EE, Broome J et al.

Alzheimers Dement

Introduction: Much of Alzheimer's disease (AD) risk is explained by age, apolipoprotein E (APOE) gen...

Alzheimer's disease (age of onset)

41527

Participants

N/A

Studies

Details PubMed

GWAS 2025-08-02

Multi-domain rule-based phenotyping algorithms enable improved GWAS signal.

Newbury A, Elhussein A et al.

NPJ Digit Med

Biobanks are a rich source of data for genome-wide association studies (GWAS). They store clinical d...

Alzheimer's disease (ADO phenotyping)

405811

Participants

N/A

Studies

Details PubMed

GWAS 2025-07-29

Whole Genome Sequence Analysis Revealed Novel Subjective Cognitive Decline-associated Genes in 10,763 Chinese.

Wang M, Sun L et al.

Genomics Proteomics Bioinformatics

Subjective cognitive decline (SCD) is widely regarded as a potential preclinical stage of Alzheimer'...

Subjective cognitive decline

Replicated

10763

Participants

N/A

Studies

Details PubMed

GWAS 2025-07-24

Genome-wide association studies of Alzheimer's disease and related disorders stratified by sex, onset age, and Apolipoprotein E genotype reveal novel risk loci in African Americans.

Sherva R, Zhu C et al.

Alzheimers Res Ther

Alzheimer's disease (AD) risk variants have been identified in European ancestry cohorts that have s...

Alzheimer's disease, proxy Alzheimer's disease or related dementias

72879

Participants

N/A

Studies

Details PubMed

GWAS 2025-07-17

Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies known and novel cross-population and ancestry-specific associations as novel risk loci for Alzheimer's disease.

Rajabli F, Benchek P et al.

Genome Biol

Limited ancestral diversity has impaired our ability to detect risk variants more prevalent in ances...

Alzheimer's disease

37382

Participants

N/A

Studies

Details PubMed

GWAS 2025-07-01

Genome-wide association meta-analysis of human olfactory identification discovers sex-specific and sex-differential genetic variants.

Förster F, Emmert D et al.

Nat Commun

Smelling is a human sense, expressing strong sexual dimorphisms. We aim to improve the knowledge of ...

Odor identification (lemon)

10132

Participants

N/A

Studies

Details PubMed

GWAS 2025-06-18

Transferability of European-derived Alzheimer's disease polygenic risk scores across multiancestry populations.

Nicolas A, Sherva R et al.

Nat Genet

A polygenic score (PGS) for Alzheimer's disease (AD) was derived recently from data on genome-wide s...

Alzheimer's disease

99796

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Ethnic-specific effects of the LILRB2-LILRB5 locus and newly identified risk loci for Alzheimer's disease in the East Asian population.

Cao H

Alzheimers Dement

Alzheimer's disease

2026-02-01

Matching heterogeneous cohorts by projected principal components reveals two novel Alzheimer's disease-associated genes in the Hispanic population.

Willett JDS

Alzheimers Dement

Alzheimer's disease

2026-02-01

No causal links between estradiol and female's brain and mental health using Mendelian randomization.

Oppenheimer H, van der Meer D et al.

Nat Commun

Brain age gap

2025-12-05

Alzheimer's disease multi-ancestry genome-wide interaction and stratified study with smoking.

Dacey R

Alzheimers Dement

Alzheimer's disease in non-smokers

2025-11-01

Genome-wide association study provides insights into the genetic basis of Lewy body dementia.

Zhu P, Jin Z et al.

Mol Psychiatry

Dementia with Lewy bodies

2025-10-09

Multi-ancestry meta-analysis identifies genetic modifiers of age-at-onset of Alzheimer's disease at known and novel loci.

Blue EE, Broome J et al.

Alzheimers Dement

Alzheimer's disease (age of onset)

2025-09-01

Multi-domain rule-based phenotyping algorithms enable improved GWAS signal.

Newbury A, Elhussein A et al.

NPJ Digit Med

Alzheimer's disease (ADO phenotyping)

2025-08-02

Whole Genome Sequence Analysis Revealed Novel Subjective Cognitive Decline-associated Genes in 10,763 Chinese.

Wang M, Sun L et al.

Genomics Proteomics Bioinformatics

Subjective cognitive decline

2025-07-29

Genome-wide association studies of Alzheimer's disease and related disorders stratified by sex, onset age, and Apolipoprotein E genotype reveal novel risk loci in African Americans.

Sherva R, Zhu C et al.

Alzheimers Res Ther

Alzheimer's disease, proxy Alzheimer's disease or related dementias

2025-07-24

Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies known and novel cross-population and ancestry-specific associations as novel risk loci for Alzheimer's disease.

Rajabli F, Benchek P et al.

Genome Biol

Alzheimer's disease

2025-07-17

Genome-wide association meta-analysis of human olfactory identification discovers sex-specific and sex-differential genetic variants.

Förster F, Emmert D et al.

Nat Commun

Odor identification (lemon)

2025-07-01

Transferability of European-derived Alzheimer's disease polygenic risk scores across multiancestry populations.

Nicolas A, Sherva R et al.

Nat Genet

Alzheimer's disease

2025-06-18