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GWAS 2025-09-29

Genetic analyses across cardiovascular traits: leveraging genetic correlations to empower locus discovery and prediction in common cardiovascular diseases.

Jordà P, Lai Y et al.

NPJ Genom Med

Common genetic variation detected by genome-wide association studies (GWAS) partially explains varia...

Atrial fibrillation (MTAG)

296021

Participants

N/A

Studies

Details PubMed

GWAS 2025-07-11

Cross-population GWAS and proteomics improve risk prediction and reveal mechanisms in atrial fibrillation.

Yuan S, Chen J et al.

Nat Commun

Atrial fibrillation (AF) is a common cardiac arrhythmia with strong genetic components, yet its unde...

Atrial fibrillation

2584013

Participants

N/A

Studies

Details PubMed

GWAS 2025-03-06

Meta-analysis of genome-wide associations and polygenic risk prediction for atrial fibrillation in more than 180,000 cases.

Roselli C, Surakka I et al.

Nat Genet

Atrial fibrillation (AF) is the most common heart rhythm abnormality and is a leading cause of heart...

Atrial fibrillation

1650345

Participants

N/A

Studies

Details PubMed

GWAS 2024-11-14

Genetic basis of right and left ventricular heart shape.

Burns R, Young WJ et al.

Nat Commun

Heart shape captures variation in cardiac structure beyond traditional phenotypes of mass and volume...

End-diastolic bi-ventricular shape (principal component 3)

35055

Participants

N/A

Studies

Details PubMed

GWAS 2024-11-13

Multi-trait association analysis reveals shared genetic loci between Alzheimer's disease and cardiovascular traits.

Koskeridis F, Fancy N et al.

Nat Commun

Several cardiovascular traits and diseases co-occur with Alzheimer's disease. We mapped their shared...

Alzheimer's disease (MTAG)

455258

Participants

N/A

Studies

Details PubMed

GWAS 2024-05-21

Deep learning of left atrial structure and function provides link to atrial fibrillation risk.

Pirruccello JP, Di Achille P et al.

Nat Commun

Increased left atrial volume and decreased left atrial function have long been associated with atria...

Left atrial maximum volume

35049

Participants

N/A

Studies

Details PubMed

GWAS 2024-04-02

Susceptibility of Atrial Fibrillation in Genetic Architecture and Heritability: A Genome-Wide Association Study in Taiwan.

Wu CI, Chen IC et al.

Heart Rhythm

No abstract available Keywords: Acute coronary syndrome; Atrial fibrillation; Genome-wide associatio...

Atrial fibrillation

10350

Participants

N/A

Studies

Details PubMed

GWAS 2024-03-13

Cardiovascular Significance and Genetics of Epicardial and Pericardial Adiposity.

Rämö JT, Kany S et al.

JAMA Cardiol

Importance: Epicardial and pericardial adipose tissue (EPAT) has been associated with cardiovascular...

Epicardial and pericardial adipose tissue

44356

Participants

N/A

Studies

Details PubMed

GWAS 2023-04-26

Druggable proteins influencing cardiac structure and function: Implications for heart failure therapies and cancer cardiotoxicity.

Schmidt AF, Bourfiss M et al.

Sci Adv

Dysfunction of either the right or left ventricle can lead to heart failure (HF) and subsequent morb...

Right ventricular end diastolic volume

35941

Participants

N/A

Studies

Details PubMed

GWAS 2023-04-18

Common and rare variants associated with cardiometabolic traits across 98,622 whole-genome sequences in the All of Us research program.

Wang X, Ryu J et al.

J Hum Genet

All of Us is a biorepository aiming to advance biomedical research by providing various types of dat...

Atrial fibrillation

98564

Participants

N/A

Studies

Details PubMed

GWAS 2023-03-14

Genetic architecture of spatial electrical biomarkers for cardiac arrhythmia and relationship with cardiovascular disease.

Young WJ, Haessler J et al.

Nat Commun

The 3-dimensional spatial and 2-dimensional frontal QRS-T angles are measures derived from the vecto...

Frontal QRS-T angle

159715

Participants

N/A

Studies

Details PubMed

GWAS 2023-01-19

Cross-ancestry genome-wide analysis of atrial fibrillation unveils disease biology and enables cardioembolic risk prediction.

Miyazawa K, Ito K et al.

Nat Genet

Atrial fibrillation (AF) is a common cardiac arrhythmia resulting in increased risk of stroke. Despi...

Atrial fibrillation

Replicated

2339188

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Genetic analyses across cardiovascular traits: leveraging genetic correlations to empower locus discovery and prediction in common cardiovascular diseases.

Jordà P, Lai Y et al.

NPJ Genom Med

Atrial fibrillation (MTAG)

2025-09-29

Cross-population GWAS and proteomics improve risk prediction and reveal mechanisms in atrial fibrillation.

Yuan S, Chen J et al.

Nat Commun

Atrial fibrillation

2025-07-11

Meta-analysis of genome-wide associations and polygenic risk prediction for atrial fibrillation in more than 180,000 cases.

Roselli C, Surakka I et al.

Nat Genet

Atrial fibrillation

2025-03-06

Genetic basis of right and left ventricular heart shape.

Burns R, Young WJ et al.

Nat Commun

End-diastolic bi-ventricular shape (principal component 3)

2024-11-14

Multi-trait association analysis reveals shared genetic loci between Alzheimer's disease and cardiovascular traits.

Koskeridis F, Fancy N et al.

Nat Commun

Alzheimer's disease (MTAG)

2024-11-13

Deep learning of left atrial structure and function provides link to atrial fibrillation risk.

Pirruccello JP, Di Achille P et al.

Nat Commun

Left atrial maximum volume

2024-05-21

Susceptibility of Atrial Fibrillation in Genetic Architecture and Heritability: A Genome-Wide Association Study in Taiwan.

Wu CI, Chen IC et al.

Heart Rhythm

Atrial fibrillation

2024-04-02

Cardiovascular Significance and Genetics of Epicardial and Pericardial Adiposity.

Rämö JT, Kany S et al.

JAMA Cardiol

Epicardial and pericardial adipose tissue

2024-03-13

Druggable proteins influencing cardiac structure and function: Implications for heart failure therapies and cancer cardiotoxicity.

Schmidt AF, Bourfiss M et al.

Sci Adv

Right ventricular end diastolic volume

2023-04-26

Common and rare variants associated with cardiometabolic traits across 98,622 whole-genome sequences in the All of Us research program.

Wang X, Ryu J et al.

J Hum Genet

Atrial fibrillation

2023-04-18

Genetic architecture of spatial electrical biomarkers for cardiac arrhythmia and relationship with cardiovascular disease.

Young WJ, Haessler J et al.

Nat Commun

Frontal QRS-T angle

2023-03-14

Cross-ancestry genome-wide analysis of atrial fibrillation unveils disease biology and enables cardioembolic risk prediction.

Miyazawa K, Ito K et al.

Nat Genet

Atrial fibrillation

2023-01-19