Active: C-reactive protein levels Clear all

GWAS 2025-01-02

A genome-wide association study of high-sensitivity C-reactive protein in a large Korean population highlights its genetic relationship with cholesterol metabolism.

Oh K, Yuk M et al.

Sci Rep

High-sensitivity C-reactive protein (hsCRP) is a representative biomarker of systemic inflammation a...

High-sensitivity C-reactive protein levels

71019

Participants

N/A

Studies

Details PubMed

GWAS 2023-03-22

No association between C-reactive protein and colorectal cancer survival: Two-sample Mendelian randomization analysis.

Choi CK, Yang JH et al.

Epidemiol Health

Objectives: Elevated C-reactive protein (CRP) levels are associated with an increased risk for color...

C-reactive protein levels

Replicated

59738

Participants

N/A

Studies

Details PubMed

GWAS 2022-11-14

Pleiotropic genetic architecture and novel loci for C-reactive protein levels.

Koskeridis F, Evangelou E et al.

Nat Commun

C-reactive protein is involved in a plethora of pathophysiological conditions. Many genetic loci ass...

C-reactive protein levels (MTAG)

575531

Participants

N/A

Studies

Details PubMed

GWAS 2022-04-22

Genetic analysis of over half a million people characterises C-reactive protein loci.

Said S, Pazoki R et al.

Nat Commun

Chronic low-grade inflammation is linked to a multitude of chronic diseases. We report the largest g...

C-reactive protein levels

575531

Participants

N/A

Studies

Details PubMed

GWAS 2022-02-18

Genetic pleiotropy between pulmonary function and age-related traits: The Long Life Family Study.

Feitosa MF, Wojczynski MK et al.

J Gerontol A Biol Sci Med Sci

Pulmonary function (PF) progressively declines with aging. Forced expiratory volume in the first sec...

Forced vital capacity and interleukin-6 levels and high-sensitivity C-reactive protein levels (pleiotropy)

6229

Participants

N/A

Studies

Details PubMed

GWAS 2020-11-23

Genome-wide association study identifies 16 genomic regions associated with circulating cytokines at birth.

Wang Y, Nudel R et al.

PLoS Genet

Circulating inflammatory markers are essential to human health and disease, and they are often dysre...

C-reactive protein levels

Replicated

8318

Participants

N/A

Studies

Details PubMed

GWAS 2020-08-05

Septic Shock: A Genomewide Association Study and Polygenic Risk Score Analysis.

D'Urso S, Rajbhandari D et al.

Twin Res Hum Genet

Previous genetic association studies have failed to identify loci robustly associated with sepsis, a...

Septic shock (28-day mortality)

493

Participants

N/A

Studies

Details PubMed

GWAS 2020-01-03

Using Mendelian randomization to evaluate the causal relationship between serum C-reactive protein levels and age-related macular degeneration.

Han X, Ong JS et al.

Eur J Epidemiol

Serum C-reactive protein (CRP), an important inflammatory marker, has been associated with age-relat...

C-reactive protein levels

418642

Participants

N/A

Studies

Details PubMed

GWAS 2019-10-17

Genetic analysis of hsCRP in American Indians: The Strong Heart Family Study.

Best LG, Balakrishnan P et al.

PLoS One

Increased serum levels of C-reactive protein (CRP), an important component of the innate immune resp...

C-reactive protein levels

1892

Participants

N/A

Studies

Details PubMed

GWAS 2019-03-06

Analysis of pleiotropic genetic effects on cognitive impairment, systemic inflammation, and plasma lipids in the Health and Retirement Study.

Lutz MW, Casanova R et al.

Neurobiol Aging

Variants associated with modulation of c-reactive protein (CRP) and plasma lipids have been investig...

Cognitive impairment and C-reactive protein levels (pleiotropy)

6545

Participants

N/A

Studies

Details PubMed

GWAS 2018-11-01

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.

Ligthart S, Vaez A et al.

Am J Hum Genet

C-reactive protein (CRP) is a sensitive biomarker of chronic low-grade inflammation and is associate...

C-reactive protein levels

204402

Participants

N/A

Studies

Details PubMed

GWAS 2018-08-01

Discovery, fine-mapping, and conditional analyses of genetic variants associated with C-reactive protein in multiethnic populations using the Metabochip in the Population Architecture using Genomics and Epidemiology (PAGE) study.

Kocarnik JM, Richard M et al.

Hum Mol Genet

C-reactive protein (CRP) is a circulating biomarker indicative of systemic inflammation. We aimed to...

C-reactive protein levels

30503

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

A genome-wide association study of high-sensitivity C-reactive protein in a large Korean population highlights its genetic relationship with cholesterol metabolism.

Oh K, Yuk M et al.

Sci Rep

High-sensitivity C-reactive protein levels

2025-01-02

No association between C-reactive protein and colorectal cancer survival: Two-sample Mendelian randomization analysis.

Choi CK, Yang JH et al.

Epidemiol Health

C-reactive protein levels

2023-03-22

Pleiotropic genetic architecture and novel loci for C-reactive protein levels.

Koskeridis F, Evangelou E et al.

Nat Commun

C-reactive protein levels (MTAG)

2022-11-14

Genetic analysis of over half a million people characterises C-reactive protein loci.

Said S, Pazoki R et al.

Nat Commun

C-reactive protein levels

2022-04-22

Genetic pleiotropy between pulmonary function and age-related traits: The Long Life Family Study.

Feitosa MF, Wojczynski MK et al.

J Gerontol A Biol Sci Med Sci

Forced vital capacity and interleukin-6 levels and high-sensitivity C-reactive protein levels (pleiotropy)

2022-02-18

Genome-wide association study identifies 16 genomic regions associated with circulating cytokines at birth.

Wang Y, Nudel R et al.

PLoS Genet

C-reactive protein levels

2020-11-23

Septic Shock: A Genomewide Association Study and Polygenic Risk Score Analysis.

D'Urso S, Rajbhandari D et al.

Twin Res Hum Genet

Septic shock (28-day mortality)

2020-08-05

Using Mendelian randomization to evaluate the causal relationship between serum C-reactive protein levels and age-related macular degeneration.

Han X, Ong JS et al.

Eur J Epidemiol

C-reactive protein levels

2020-01-03

Genetic analysis of hsCRP in American Indians: The Strong Heart Family Study.

Best LG, Balakrishnan P et al.

PLoS One

C-reactive protein levels

2019-10-17

Analysis of pleiotropic genetic effects on cognitive impairment, systemic inflammation, and plasma lipids in the Health and Retirement Study.

Lutz MW, Casanova R et al.

Neurobiol Aging

Cognitive impairment and C-reactive protein levels (pleiotropy)

2019-03-06

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.

Ligthart S, Vaez A et al.

Am J Hum Genet

C-reactive protein levels

2018-11-01

Discovery, fine-mapping, and conditional analyses of genetic variants associated with C-reactive protein in multiethnic populations using the Metabochip in the Population Architecture using Genomics and Epidemiology (PAGE) study.

Kocarnik JM, Richard M et al.

Hum Mol Genet

C-reactive protein levels

2018-08-01