Active: Coronary artery calcification Clear all

GWAS 2025-03-31

A genome-wide association study of imaging-defined atherosclerosis.

Gummesson A, Lundmark P et al.

Nat Commun

Imaging-defined atherosclerosis represents an intermediate phenotype of atherosclerotic cardiovascul...

Coronary artery calcification

26000

Participants

N/A

Studies

Details PubMed

GWAS 2024-06-27

Association of <i>PHACTR1</i> with Coronary Artery Calcium Differs by Sex and Cigarette Smoking.

Voorhies K, Young K et al.

J Cardiovasc Dev Dis

Coronary artery calcium (CAC) is a marker of subclinical atherosclerosis and is a complex heritable ...

Coronary artery calcification

Replicated

7259

Participants

N/A

Studies

Details PubMed

GWAS 2023-09-28

Multi-ancestry genome-wide study identifies effector genes and druggable pathways for coronary artery calcification.

Kavousi M, Bos MM et al.

Nat Genet

Coronary artery calcification (CAC), a measure of subclinical atherosclerosis, predicts future sympt...

Coronary artery calcification

36720

Participants

N/A

Studies

Details PubMed

GWAS 2022-10-04

Clinical, genetic, and experimental increase in soluble urokinase plasminogen activator receptor levels promotes atherosclerosis.

Hindy G, Tyrrell DJ et al.

J Clin Invest

People with kidney disease are disproportionately affected by atherosclerosis for unclear reasons. S...

Soluble urokinase plasminogen activator receptor levels

Replicated

25114

Participants

N/A

Studies

Details PubMed

GWAS 2021-07-09

Multiethnic Genome-wide Association Study of Subclinical Atherosclerosis in Individuals with Type 2 Diabetes.

Lu Y, Dimitrov L et al.

Circ Genom Precis Med

Coronary artery calcification (CAC) and carotid artery intima-media thickness (cIMT) are measures of...

Carotid artery intima-media thickness in type 2 diabetes

838

Participants

N/A

Studies

Details PubMed

GWAS 2019-03-28

Genome-wide association study of coronary artery calcification in asymptomatic Korean populations.

Choi SY, Shin E et al.

PLoS One

Epidemiologic evidence indicates that the prevalence and severity of coronary artery disease vary de...

Severe coronary artery calcification

Replicated

1688

Participants

N/A

Studies

Details PubMed

GWAS 2013-10-03

Genome-wide association study of gene by smoking interactions in coronary artery calcification.

Polfus LM, Smith JA et al.

PLoS One

Many GWAS have identified novel loci associated with common diseases, but have focused only on main ...

Coronary artery calcification (smoking interaction)

Replicated

1940

Participants

N/A

Studies

Details PubMed

GWAS 2013-07-19

Genetics of coronary artery calcification among African Americans, a meta-analysis.

Wojczynski MK, Li M et al.

BMC Med Genet

Coronary heart disease (CHD) is the major cause of death in the United States. Coronary artery calci...

Coronary artery calcification

Replicated

15815

Participants

N/A

Studies

Details PubMed

GWAS 2013-03-13

Genome-wide association study of coronary and aortic calcification implicates risk loci for coronary artery disease and myocardial infarction.

van Setten J, Isgum I et al.

Atherosclerosis

Arterial calcification is a well-known risk factor for coronary artery disease (CAD) and myocardial ...

Coronary artery calcification

2620

Participants

N/A

Studies

Details PubMed

GWAS 2013-02-08

Risk loci for coronary artery calcification replicated at 9p21 and 6q24 in the Heinz Nixdorf Recall Study.

Pechlivanis S, Mühleisen TW et al.

BMC Med Genet

Atherosclerosis is the primary cause of coronary heart disease (CHD), preceding the onset of cardiov...

Coronary artery calcification

4329

Participants

N/A

Studies

Details PubMed

GWAS 2011-12-05

Genome-wide association study for coronary artery calcification with follow-up in myocardial infarction.

O'Donnell CJ, Kavousi M et al.

Circulation

Coronary artery calcification (CAC) detected by computed tomography is a noninvasive measure of coro...

Coronary artery calcification

Replicated

15993

Participants

N/A

Studies

Details PubMed

GWAS 2008-12-17

A null mutation in human APOC3 confers a favorable plasma lipid profile and apparent cardioprotection.

Pollin TI, Damcott CM et al.

Science

Apolipoprotein C-III (apoC-III) inhibits triglyceride hydrolysis and has been implicated in coronary...

Triglycerides

Replicated

1507

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

A genome-wide association study of imaging-defined atherosclerosis.

Gummesson A, Lundmark P et al.

Nat Commun

Coronary artery calcification

2025-03-31

Association of <i>PHACTR1</i> with Coronary Artery Calcium Differs by Sex and Cigarette Smoking.

Voorhies K, Young K et al.

J Cardiovasc Dev Dis

Coronary artery calcification

2024-06-27

Multi-ancestry genome-wide study identifies effector genes and druggable pathways for coronary artery calcification.

Kavousi M, Bos MM et al.

Nat Genet

Coronary artery calcification

2023-09-28

Clinical, genetic, and experimental increase in soluble urokinase plasminogen activator receptor levels promotes atherosclerosis.

Hindy G, Tyrrell DJ et al.

J Clin Invest

Soluble urokinase plasminogen activator receptor levels

2022-10-04

Multiethnic Genome-wide Association Study of Subclinical Atherosclerosis in Individuals with Type 2 Diabetes.

Lu Y, Dimitrov L et al.

Circ Genom Precis Med

Carotid artery intima-media thickness in type 2 diabetes

2021-07-09

Genome-wide association study of coronary artery calcification in asymptomatic Korean populations.

Choi SY, Shin E et al.

PLoS One

Severe coronary artery calcification

2019-03-28

Genome-wide association study of gene by smoking interactions in coronary artery calcification.

Polfus LM, Smith JA et al.

PLoS One

Coronary artery calcification (smoking interaction)

2013-10-03

Genetics of coronary artery calcification among African Americans, a meta-analysis.

Wojczynski MK, Li M et al.

BMC Med Genet

Coronary artery calcification

2013-07-19

Genome-wide association study of coronary and aortic calcification implicates risk loci for coronary artery disease and myocardial infarction.

van Setten J, Isgum I et al.

Atherosclerosis

Coronary artery calcification

2013-03-13

Risk loci for coronary artery calcification replicated at 9p21 and 6q24 in the Heinz Nixdorf Recall Study.

Pechlivanis S, Mühleisen TW et al.

BMC Med Genet

Coronary artery calcification

2013-02-08

Genome-wide association study for coronary artery calcification with follow-up in myocardial infarction.

O'Donnell CJ, Kavousi M et al.

Circulation

Coronary artery calcification

2011-12-05

A null mutation in human APOC3 confers a favorable plasma lipid profile and apparent cardioprotection.

Pollin TI, Damcott CM et al.

Science

Triglycerides

2008-12-17