Active: Diastolic blood pressure Clear all

GWAS 2024-03-09

A genome-wide association study based on the China Kadoorie Biobank identifies genetic associations between snoring and cardiometabolic traits.

Zhu Y, Zhuang Z et al.

Commun Biol

Despite the high prevalence of snoring in Asia, little is known about the genetic etiology of snorin...

Snoring

100626

Participants

N/A

Studies

Details PubMed

GWAS 2023-02-09

GWAS on retinal vasculometry phenotypes.

Jiang X, Hysi PG et al.

PLoS Genet

The eye is the window through which light is transmitted and visual sensory signalling originates. I...

Retinal arteriolar tortuosity

Replicated

57785

Participants

N/A

Studies

Details PubMed

GWAS 2022-09-20

Leveraging omics data to boost the power of genome-wide association studies.

Lin Z, Knutson KA et al.

HGG Adv

Genome-wide association studies (GWASs) have successfully identified many genetic variants and risk ...

Hypertension

91620

Participants

N/A

Studies

Details PubMed

GWAS 2022-07-25

Genome-wide variance quantitative trait locus analysis suggests small interaction effects in blood pressure traits.

Shi G

Sci Rep

Genome-wide variance quantitative trait loci (vQTL) analysis complements genome-wide association stu...

Systolic blood pressure

396077

Participants

N/A

Studies

Details PubMed

GWAS 2022-07-15

Genetic Contributors of Efficacy and Adverse Metabolic Effects of Chlorthalidone in African Americans from the Genetics of Hypertension Associated Treatments (GenHAT) Study.

Armstrong ND, Srinivasasainagendra V et al.

Genes (Basel)

Hypertension is a leading risk factor for cardiovascular disease mortality. African Americans (AAs) ...

Diastolic blood pressure response to chlorthalidone in hypertension

Replicated

4552

Participants

N/A

Studies

Details PubMed

GWAS 2022-06-02

Insights From a Large-Scale Whole-Genome Sequencing Study of Systolic Blood Pressure, Diastolic Blood Pressure, and Hypertension.

Kelly TN, Sun X et al.

Hypertension

The availability of whole-genome sequencing data in large studies has enabled the assessment of codi...

Diastolic blood pressure

Replicated

764135

Participants

N/A

Studies

Details PubMed

GWAS 2022-01-07

Identification of genetic loci simultaneously associated with multiple cardiometabolic traits.

Wood AC, Arora A et al.

Nutr Metab Cardiovasc Dis

Background and aims: Cardiometabolic disorders (CMD) arise from a constellation of features such as ...

Diastolic blood pressure

453413

Participants

N/A

Studies

Details PubMed

GWAS 2022-01-06

Genome-wide pleiotropy analysis identifies novel blood pressure variants and improves its polygenic risk scores.

Zhu X, Zhu L et al.

Genet Epidemiol

Systolic and diastolic blood pressure (S/DBP) are highly correlated modifiable risk factors for card...

Blood pressure (pleiotropy model 1 DBP adjusted for estimated causal effects x SBP)

1076492

Participants

N/A

Studies

Details PubMed

GWAS 2021-11-11

Shared Genetic Liability and Causal Associations Between Major Depressive Disorder and Cardiovascular Diseases.

Zhang F, Cao H et al.

Front Cardiovasc Med

Major depressive disorder (MDD) is phenotypically associated with cardiovascular diseases (CVD). We ...

Major depressive disorder or stroke (pleiotropy)

927055

Participants

N/A

Studies

Details PubMed

GWAS 2021-06-03

Genome-wide association study on blood pressure traits in the Iranian population suggests ZBED9 as a new locus for hypertension.

Kolifarhood G, Sabour S et al.

Sci Rep

High blood pressure is the heritable risk factor for cardiovascular and kidney diseases. Genome-wide...

Systolic blood pressure

Replicated

6185

Participants

N/A

Studies

Details PubMed

GWAS 2021-05-17

A Genome-Wide Association Study for Hypertensive Kidney Disease in Korean Men.

Kim HR, Jin HS et al.

Genes (Basel)

Hypertension is one of the major risk factors for chronic kidney disease (CKD), and the coexistence ...

Hypertensive renal disease

Replicated

3283

Participants

N/A

Studies

Details PubMed

GWAS 2021-05-06

Type 2 diabetes is causally associated with reduced serum osteocalcin: A genome-wide association and Mendelian randomization study.

Zeng H, Ge J et al.

J Bone Miner Res

Recent advances indicate that bone and energy metabolism are closely related. However, little direct...

Serum 25-Hydroxyvitamin D levels

Replicated

4665

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

A genome-wide association study based on the China Kadoorie Biobank identifies genetic associations between snoring and cardiometabolic traits.

Zhu Y, Zhuang Z et al.

Commun Biol

Snoring

2024-03-09

GWAS on retinal vasculometry phenotypes.

Jiang X, Hysi PG et al.

PLoS Genet

Retinal arteriolar tortuosity

2023-02-09

Leveraging omics data to boost the power of genome-wide association studies.

Lin Z, Knutson KA et al.

HGG Adv

Hypertension

2022-09-20

Genome-wide variance quantitative trait locus analysis suggests small interaction effects in blood pressure traits.

Shi G

Sci Rep

Systolic blood pressure

2022-07-25

Genetic Contributors of Efficacy and Adverse Metabolic Effects of Chlorthalidone in African Americans from the Genetics of Hypertension Associated Treatments (GenHAT) Study.

Armstrong ND, Srinivasasainagendra V et al.

Genes (Basel)

Diastolic blood pressure response to chlorthalidone in hypertension

2022-07-15

Insights From a Large-Scale Whole-Genome Sequencing Study of Systolic Blood Pressure, Diastolic Blood Pressure, and Hypertension.

Kelly TN, Sun X et al.

Hypertension

Diastolic blood pressure

2022-06-02

Identification of genetic loci simultaneously associated with multiple cardiometabolic traits.

Wood AC, Arora A et al.

Nutr Metab Cardiovasc Dis

Diastolic blood pressure

2022-01-07

Genome-wide pleiotropy analysis identifies novel blood pressure variants and improves its polygenic risk scores.

Zhu X, Zhu L et al.

Genet Epidemiol

Blood pressure (pleiotropy model 1 DBP adjusted for estimated causal effects x SBP)

2022-01-06

Shared Genetic Liability and Causal Associations Between Major Depressive Disorder and Cardiovascular Diseases.

Zhang F, Cao H et al.

Front Cardiovasc Med

Major depressive disorder or stroke (pleiotropy)

2021-11-11

Genome-wide association study on blood pressure traits in the Iranian population suggests ZBED9 as a new locus for hypertension.

Kolifarhood G, Sabour S et al.

Sci Rep

Systolic blood pressure

2021-06-03

A Genome-Wide Association Study for Hypertensive Kidney Disease in Korean Men.

Kim HR, Jin HS et al.

Genes (Basel)

Hypertensive renal disease

2021-05-17

Type 2 diabetes is causally associated with reduced serum osteocalcin: A genome-wide association and Mendelian randomization study.

Zeng H, Ge J et al.

J Bone Miner Res

Serum 25-Hydroxyvitamin D levels

2021-05-06