Active: Dyslexia Clear all

GWAS 2024-09-28

Imaging genetics of language network functional connectivity reveals links with language-related abilities, dyslexia and handedness.

Amelink JS, Postema MC et al.

Commun Biol

Language is supported by a distributed network of brain regions with a particular contribution from ...

Brain language network hemispheric differences in intrahemispheric functional connectivity

29681

Participants

N/A

Studies

Details PubMed

GWAS 2024-03-27

A genome-wide association study of Chinese and English language phenotypes in Hong Kong Chinese children.

Lin YP, Shi Y et al.

NPJ Sci Learn

Dyslexia and developmental language disorders are important learning difficulties. However, their ge...

Pair Cancellation

1048

Participants

N/A

Studies

Details PubMed

GWAS 2022-10-20

Discovery of 42 genome-wide significant loci associated with dyslexia.

Doust C, Fontanillas P et al.

Nat Genet

Reading and writing are crucial life skills but roughly one in ten children are affected by dyslexia...

Dyslexia

1138870

Participants

N/A

Studies

Details PubMed

GWAS 2019-11-29

Genetic effects on planum temporale asymmetry and their limited relevance to neurodevelopmental disorders, intelligence or educational attainment.

Carrion-Castillo A, Pepe A et al.

Cortex

Previous studies have suggested that altered asymmetry of the planum temporale (PT) is associated wi...

Left planum temporale grey matter volume

18037

Participants

N/A

Studies

Details PubMed

GWAS 2019-02-11

Genome-wide association scan identifies new variants associated with a cognitive predictor of dyslexia.

Gialluisi A, Andlauer TFM et al.

Transl Psychiatry

Developmental dyslexia (DD) is one of the most prevalent learning disorders, with high impact on sch...

Rapid automised naming of digits

2563

Participants

N/A

Studies

Details PubMed

GWAS 2014-09-16

Common variation near ROBO2 is associated with expressive vocabulary in infancy.

St Pourcain B, Cents RA et al.

Nat Commun

Twin studies suggest that expressive vocabulary at ~24 months is modestly heritable. However, the ge...

Expressive vocabulary in infants

Replicated

19708

Participants

N/A

Studies

Details PubMed

GWAS 2013-09-12

Common variants in left/right asymmetry genes and pathways are associated with relative hand skill.

Brandler WM, Morris AP et al.

PLoS Genet

Humans display structural and functional asymmetries in brain organization, strikingly with respect ...

Relative hand skill in reading disability

728

Participants

N/A

Studies

Details PubMed

GWAS 2013-02-19

A common variant in myosin-18B contributes to mathematical abilities in children with dyslexia and intraparietal sulcus variability in adults.

Ludwig KU, Sämann P et al.

Transl Psychiatry

The ability to perform mathematical tasks is required in everyday life. Although heritability estima...

Mathematical ability in children with dyslexia

Replicated

710

Participants

N/A

Studies

Details PubMed

GWAS 2010-11-09

PCSK6 is associated with handedness in individuals with dyslexia.

Scerri TS, Brandler WM et al.

Hum Mol Genet

Approximately 90% of humans are right-handed. Handedness is a heritable trait, yet the genetic basis...

Handedness in dyslexia

Replicated

765

Participants

N/A

Studies

Details PubMed

GWAS 2009-09-29

First genome-wide association scan on neurophysiological endophenotypes points to trans-regulation effects on SLC2A3 in dyslexic children.

Roeske D, Ludwig KU et al.

Mol Psychiatry

Dyslexia is one of the most common learning disorders affecting about 5% of all school-aged children...

Speech perception in dyslexia

Replicated

386

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Imaging genetics of language network functional connectivity reveals links with language-related abilities, dyslexia and handedness.

Amelink JS, Postema MC et al.

Commun Biol

Brain language network hemispheric differences in intrahemispheric functional connectivity

2024-09-28

A genome-wide association study of Chinese and English language phenotypes in Hong Kong Chinese children.

Lin YP, Shi Y et al.

NPJ Sci Learn

Pair Cancellation

2024-03-27

Discovery of 42 genome-wide significant loci associated with dyslexia.

Doust C, Fontanillas P et al.

Nat Genet

Dyslexia

2022-10-20

Genetic effects on planum temporale asymmetry and their limited relevance to neurodevelopmental disorders, intelligence or educational attainment.

Carrion-Castillo A, Pepe A et al.

Cortex

Left planum temporale grey matter volume

2019-11-29

Genome-wide association scan identifies new variants associated with a cognitive predictor of dyslexia.

Gialluisi A, Andlauer TFM et al.

Transl Psychiatry

Rapid automised naming of digits

2019-02-11

Common variation near ROBO2 is associated with expressive vocabulary in infancy.

St Pourcain B, Cents RA et al.

Nat Commun

Expressive vocabulary in infants

2014-09-16

Common variants in left/right asymmetry genes and pathways are associated with relative hand skill.

Brandler WM, Morris AP et al.

PLoS Genet

Relative hand skill in reading disability

2013-09-12

A common variant in myosin-18B contributes to mathematical abilities in children with dyslexia and intraparietal sulcus variability in adults.

Ludwig KU, Sämann P et al.

Transl Psychiatry

Mathematical ability in children with dyslexia

2013-02-19

PCSK6 is associated with handedness in individuals with dyslexia.

Scerri TS, Brandler WM et al.

Hum Mol Genet

Handedness in dyslexia

2010-11-09

First genome-wide association scan on neurophysiological endophenotypes points to trans-regulation effects on SLC2A3 in dyslexic children.

Roeske D, Ludwig KU et al.

Mol Psychiatry

Speech perception in dyslexia

2009-09-29