Active: Executive function Clear all

GWAS 2025-11-04

The Genetic Architecture of the Human Corpus Callosum and its Subregions.

Bhatt RR, Gadewar SP et al.

Nat Commun

The corpus callosum (CC) is the largest set of white matter fibers connecting the two hemispheres of...

Corpus callosum total area

Replicated

51450

Participants

N/A

Studies

Details PubMed

GWAS 2025-03-20

Novel modelling approaches to elucidate the genetic architecture of resilience to Alzheimer's disease.

Phillips JM, Dumitrescu LC et al.

Brain

Up to 30% of older adults meet pathological criteria for a diagnosis of Alzheimer's disease at autop...

Residual cognitive resilience

20513

Participants

N/A

Studies

Details PubMed

GWAS 2025-02-01

GenomicSEM Modelling of Diverse Executive Function GWAS Improves Gene Discovery.

Perry LC, Chevalier N et al.

Behav Genet

Previous research has supported the use of latent variables as the gold-standard in measuring execut...

Common executive function

266413

Participants

N/A

Studies

Details PubMed

GWAS 2024-06-18

Genetic influences on brain and cognitive health and their interactions with cardiovascular conditions and depression.

Zhukovsky P, Tio ES et al.

Nat Commun

Approximately 40% of dementia cases could be prevented or delayed by modifiable risk factors related...

Global cortical thickness (GlobalMeanMean)

34552

Participants

N/A

Studies

Details PubMed

GWAS 2023-12-21

A Genome-Wide Interaction Study of Erythrocyte ω3 Polyunsaturated Fatty Acid Species and Memory in The Framingham Heart Study Offspring Cohort.

Annevelink CE, Westra J et al.

J Nutr

Cognitive decline, and more specifically Alzheimer's disease, continues to increase in prevalence gl...

Alpha-linoleic acid levels and Trail making test A (interaction)

1620

Participants

N/A

Studies

Details PubMed

GWAS 2023-07-27

Trans-ancestry meta-analysis of genome wide association studies of inhibitory control.

Arnatkeviciute A, Lemire M et al.

Mol Psychiatry

Deficits in effective executive function, including inhibitory control are associated with risk for ...

Mean go reaction time

14844

Participants

N/A

Studies

Details PubMed

GWAS 2023-05-26

The genetic architecture of fornix white matter microstructure and their involvement in neuropsychiatric disorders.

Ou YN, Ge YJ et al.

Transl Psychiatry

The fornix is a white matter bundle located in the center of the hippocampaldiencephalic limbic circ...

Fornix white matter microstructure (fractional anisotropy)

Replicated

34445

Participants

N/A

Studies

Details PubMed

GWAS 2023-05-23

Genetic Variants Associated with Longitudinal Cognitive Performance in Older Breast Cancer Patients and Controls.

Nudelman K, Nho K et al.

Cancers (Basel)

There have been no published genome-wide studies of the genetics of cancer- and treatment-related co...

Longitudinal cognitive performance (attention, processing and executive function) x breast cancer interaction

665

Participants

N/A

Studies

Details PubMed

GWAS 2023-03-27

Genome-wide association study of population-standardised cognitive performance phenotypes in a rural South African community.

Soo CC, Brandenburg JT et al.

Commun Biol

Cognitive function is an indicator for global physical and mental health, and cognitive impairment h...

Executive function

1887

Participants

N/A

Studies

Details PubMed

GWAS 2023-01-26

Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains.

Demontis D, Walters GB et al.

Nat Genet

Attention-deficit hyperactivity disorder (ADHD) is a prevalent neurodevelopmental disorder with a ma...

Attention deficit hyperactivity disorder

225534

Participants

N/A

Studies

Details PubMed

GWAS 2022-12-05

Genome-wide association study of executive function in a multi-ethnic cohort implicates LINC01362: Results from the northern Manhattan study.

Dueker N, Wang L et al.

Neurobiol Aging

Executive function is a cognitive domain with sizable heritability representing higher-order cogniti...

Executive function

1077

Participants

N/A

Studies

Details PubMed

GWAS 2022-07-14

Genome-wide Association Study Shows That Executive Functioning Is Influenced by GABAergic Processes and Is a Neurocognitive Genetic Correlate of Psychiatric Disorders.

Hatoum AS, Morrison CL et al.

Biol Psychiatry

Deficits in executive functions (EFs), cognitive processes that control goal-directed behaviors, are...

Common executive function

427037

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

The Genetic Architecture of the Human Corpus Callosum and its Subregions.

Bhatt RR, Gadewar SP et al.

Nat Commun

Corpus callosum total area

2025-11-04

Novel modelling approaches to elucidate the genetic architecture of resilience to Alzheimer's disease.

Phillips JM, Dumitrescu LC et al.

Brain

Residual cognitive resilience

2025-03-20

GenomicSEM Modelling of Diverse Executive Function GWAS Improves Gene Discovery.

Perry LC, Chevalier N et al.

Behav Genet

Common executive function

2025-02-01

Genetic influences on brain and cognitive health and their interactions with cardiovascular conditions and depression.

Zhukovsky P, Tio ES et al.

Nat Commun

Global cortical thickness (GlobalMeanMean)

2024-06-18

A Genome-Wide Interaction Study of Erythrocyte ω3 Polyunsaturated Fatty Acid Species and Memory in The Framingham Heart Study Offspring Cohort.

Annevelink CE, Westra J et al.

J Nutr

Alpha-linoleic acid levels and Trail making test A (interaction)

2023-12-21

Trans-ancestry meta-analysis of genome wide association studies of inhibitory control.

Arnatkeviciute A, Lemire M et al.

Mol Psychiatry

Mean go reaction time

2023-07-27

The genetic architecture of fornix white matter microstructure and their involvement in neuropsychiatric disorders.

Ou YN, Ge YJ et al.

Transl Psychiatry

Fornix white matter microstructure (fractional anisotropy)

2023-05-26

Genetic Variants Associated with Longitudinal Cognitive Performance in Older Breast Cancer Patients and Controls.

Nudelman K, Nho K et al.

Cancers (Basel)

Longitudinal cognitive performance (attention, processing and executive function) x breast cancer interaction

2023-05-23

Genome-wide association study of population-standardised cognitive performance phenotypes in a rural South African community.

Soo CC, Brandenburg JT et al.

Commun Biol

Executive function

2023-03-27

Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains.

Demontis D, Walters GB et al.

Nat Genet

Attention deficit hyperactivity disorder

2023-01-26

Genome-wide association study of executive function in a multi-ethnic cohort implicates LINC01362: Results from the northern Manhattan study.

Dueker N, Wang L et al.

Neurobiol Aging

Executive function

2022-12-05

Genome-wide Association Study Shows That Executive Functioning Is Influenced by GABAergic Processes and Is a Neurocognitive Genetic Correlate of Psychiatric Disorders.

Hatoum AS, Morrison CL et al.

Biol Psychiatry

Common executive function

2022-07-14