Active: General cognitive ability Clear all

GWAS 2023-03-29

General dimensions of human brain morphometry inferred from genome-wide association data.

Fürtjes AE, Arathimos R et al.

Hum Brain Mapp

Understanding the neurodegenerative mechanisms underlying cognitive decline in the general populatio...

Brain stem volume (UKB data field 26526)

36778

Participants

N/A

Studies

Details PubMed

GWAS 2019-09-18

Genome-Wide Homozygosity Mapping Reveals Genes Associated With Cognitive Ability in Children From Saudi Arabia.

Kornilov SA, Tan M et al.

Front Genet

Recent studies of the genetic foundations of cognitive ability rely on large samples (in extreme, hu...

General cognitive ability

354

Participants

N/A

Studies

Details PubMed

GWAS 2019-08-01

Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways.

Lam M, Hill WD et al.

Am J Hum Genet

Susceptibility to schizophrenia is inversely correlated with general cognitive ability at both the p...

Cognitive ability, years of educational attainment or schizophrenia (pleiotropy)

556676

Participants

N/A

Studies

Details PubMed

GWAS 2019-06-01

Genetic Contributions to Health Literacy.

Fawns-Ritchie C, Davies G et al.

Twin Res Hum Genet

Higher health literacy is associated with higher cognitive function and better health. Despite its w...

Health literacy

5783

Participants

N/A

Studies

Details PubMed

GWAS 2017-11-28

Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets.

Lam M, Trampush JW et al.

Cell Rep

Here, we present a large (n = 107,207) genome-wide association study (GWAS) of general cognitive abi...

Cognitive ability

107207

Participants

N/A

Studies

Details PubMed

GWAS 2017-08-10

Haplotype-based association analysis of general cognitive ability in Generation Scotland, the English Longitudinal Study of Ageing, and UK Biobank.

Howard DM, Adams MJ et al.

Wellcome Open Res

Cognitive ability is a heritable trait with a polygenic architecture, for which several associated v...

General cognitive ability

Replicated

48002

Participants

N/A

Studies

Details PubMed

GWAS 2015-05-12

Common genetic variation and schizophrenia polygenic risk influence neurocognitive performance in young adulthood.

Hatzimanolis A, Bhatnagar P et al.

Am J Med Genet B Neuropsychiatr Genet

Neurocognitive abilities constitute complex traits with considerable heritability. Impaired neurocog...

Endophenotypes for schizophrenia in healthy individuals

Replicated

2642

Participants

N/A

Studies

Details PubMed

GWAS 2014-11-10

Results of a "GWAS plus:" general cognitive ability is substantially heritable and massively polygenic.

Kirkpatrick RM, McGue M et al.

PLoS One

We carried out a genome-wide association study (GWAS) for general cognitive ability (GCA) plus three...

General cognitive ability

7100

Participants

N/A

Studies

Details PubMed

GWAS 2014-02-01

Molecular genetic evidence for overlap between general cognitive ability and risk for schizophrenia: a report from the Cognitive Genomics consorTium (COGENT).

Lencz T, Knowles E et al.

Mol Psychiatry

It has long been recognized that generalized deficits in cognitive ability represent a core componen...

General cognitive ability

4896

Participants

N/A

Studies

Details PubMed

GWAS 2012-02-28

Genome-wide association study of intelligence: additive effects of novel brain expressed genes.

Loo SK, Shtir C et al.

J Am Acad Child Adolesc Psychiatry

Objective: The purpose of the present study was to identify common genetic variants that are associa...

Intelligence

656

Participants

N/A

Studies

Details PubMed

GWAS 2010-03-21

A three-stage genome-wide association study of general cognitive ability: hunting the small effects.

Davis OS, Butcher LM et al.

Behav Genet

Childhood general cognitive ability (g) is important for a wide range of outcomes in later life, fro...

Cognitive ability

Replicated

3479

Participants

N/A

Studies

Details PubMed

GWAS 2008-01-22

Genome-wide quantitative trait locus association scan of general cognitive ability using pooled DNA and 500K single nucleotide polymorphism microarrays.

Butcher LM, Davis OS et al.

Genes Brain Behav

General cognitive ability (g), which refers to what cognitive abilities have in common, is an import...

General cognitive ability

Replicated

4055

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

General dimensions of human brain morphometry inferred from genome-wide association data.

Fürtjes AE, Arathimos R et al.

Hum Brain Mapp

Brain stem volume (UKB data field 26526)

2023-03-29

Genome-Wide Homozygosity Mapping Reveals Genes Associated With Cognitive Ability in Children From Saudi Arabia.

Kornilov SA, Tan M et al.

Front Genet

General cognitive ability

2019-09-18

Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways.

Lam M, Hill WD et al.

Am J Hum Genet

Cognitive ability, years of educational attainment or schizophrenia (pleiotropy)

2019-08-01

Genetic Contributions to Health Literacy.

Fawns-Ritchie C, Davies G et al.

Twin Res Hum Genet

Health literacy

2019-06-01

Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets.

Lam M, Trampush JW et al.

Cell Rep

Cognitive ability

2017-11-28

Haplotype-based association analysis of general cognitive ability in Generation Scotland, the English Longitudinal Study of Ageing, and UK Biobank.

Howard DM, Adams MJ et al.

Wellcome Open Res

General cognitive ability

2017-08-10

Common genetic variation and schizophrenia polygenic risk influence neurocognitive performance in young adulthood.

Hatzimanolis A, Bhatnagar P et al.

Am J Med Genet B Neuropsychiatr Genet

Endophenotypes for schizophrenia in healthy individuals

2015-05-12

Results of a "GWAS plus:" general cognitive ability is substantially heritable and massively polygenic.

Kirkpatrick RM, McGue M et al.

PLoS One

General cognitive ability

2014-11-10

Molecular genetic evidence for overlap between general cognitive ability and risk for schizophrenia: a report from the Cognitive Genomics consorTium (COGENT).

Lencz T, Knowles E et al.

Mol Psychiatry

General cognitive ability

2014-02-01

Genome-wide association study of intelligence: additive effects of novel brain expressed genes.

Loo SK, Shtir C et al.

J Am Acad Child Adolesc Psychiatry

Intelligence

2012-02-28

A three-stage genome-wide association study of general cognitive ability: hunting the small effects.

Davis OS, Butcher LM et al.

Behav Genet

Cognitive ability

2010-03-21

Genome-wide quantitative trait locus association scan of general cognitive ability using pooled DNA and 500K single nucleotide polymorphism microarrays.

Butcher LM, Davis OS et al.

Genes Brain Behav

General cognitive ability

2008-01-22