Health & Traits Publications

International League Against Epilepsy Consortium on Complex Epilepsies

Nat Genet

Epilepsy is a highly heritable disorder affecting over 50 million people worldwide, of which about o...

Epilepsy

Buono RJ, Bradfield JP et al.

Genes (Basel)

We performed a genome-wide association study (GWAS) to identify genetic variation associated with co...

Generalized epilepsy

Wolking S, Schulz H et al.

Pharmacogenomics

Aim: Pharmacoresistance is a major burden in epilepsy treatment. We aimed to identify genetic biomar...

Response to antiepileptic drugs in genetic generalized epilepsy

Stevelink R, Pangilinan F et al.

Mol Genet Metab Rep

Altered vitamin B6 metabolism due to pathogenic variants in the gene PNPO causes early onset epilept...

Pyridoxal 5'-phosphate levels

Steffens M, Leu C et al.

Hum Mol Genet

Genetic generalized epilepsies (GGEs) have a lifetime prevalence of 0.3% and account for 20-30% of a...

Generalized epilepsy