Active: Glycine levels Clear all

GWAS 2022-09-08

Integrative analysis of metabolite GWAS illuminates the molecular basis of pleiotropy and genetic correlation.

Smith CJ, Sinnott-Armstrong N et al.

Elife

Pleiotropy and genetic correlation are widespread features in genome-wide association studies (GWAS)...

Glycine levels

94464

Participants

N/A

Studies

Details PubMed

GWAS 2022-03-24

Integrative Pathway Analysis of SNP and Metabolite Data Using a Hierarchical Structural Component Model.

Jung T, Jung Y et al.

Front Genet

Integrative multi-omics analysis has become a useful tool to understand molecular mechanisms and dru...

Dimethylglycine levels

627

Participants

N/A

Studies

Details PubMed

GWAS 2021-04-07

The association of genetically determined serum glycine with cardiovascular risk in East Asians.

Chang X, Wang L et al.

Nutr Metab Cardiovasc Dis

Background and aims: Glycine is involved in a wide range of metabolic pathways and increased circula...

Glycine levels

1324

Participants

N/A

Studies

Details PubMed

GWAS 2019-05-09

Genetic Determinants of Circulating Glycine Levels and Risk of Coronary Artery Disease.

Jia Q, Han Y et al.

J Am Heart Assoc

Background Recent studies have revealed sexually dimorphic associations between the carbamoyl-phosph...

Glycine levels

19112

Participants

N/A

Studies

Details PubMed

GWAS 2019-03-05

Assessing the causal association of glycine with risk of cardio-metabolic diseases.

Wittemans LBL, Lotta LA et al.

Nat Commun

Circulating levels of glycine have previously been associated with lower incidence of coronary heart...

Glycine levels

80003

Participants

N/A

Studies

Details PubMed

GWAS 2018-05-01

Identification of seven novel loci associated with amino acid levels using single-variant and gene-based tests in 8545 Finnish men from the METSIM study.

Teslovich TM, Kim DS et al.

Hum Mol Genet

Comprehensive metabolite profiling captures many highly heritable traits, including amino acid level...

Alanine levels

Replicated

11136

Participants

N/A

Studies

Details PubMed

GWAS 2016-01-29

Genome-wide association study and targeted metabolomics identifies sex-specific association of CPS1 with coronary artery disease.

Hartiala JA, Tang WH et al.

Nat Commun

Metabolites derived from dietary choline and L-carnitine, such as trimethylamine N-oxide and betaine...

Betaine levels in individuals undergoing cardiac evaluation

Replicated

3880

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Integrative analysis of metabolite GWAS illuminates the molecular basis of pleiotropy and genetic correlation.

Smith CJ, Sinnott-Armstrong N et al.

Elife

Glycine levels

2022-09-08

Integrative Pathway Analysis of SNP and Metabolite Data Using a Hierarchical Structural Component Model.

Jung T, Jung Y et al.

Front Genet

Dimethylglycine levels

2022-03-24

The association of genetically determined serum glycine with cardiovascular risk in East Asians.

Chang X, Wang L et al.

Nutr Metab Cardiovasc Dis

Glycine levels

2021-04-07

Genetic Determinants of Circulating Glycine Levels and Risk of Coronary Artery Disease.

Jia Q, Han Y et al.

J Am Heart Assoc

Glycine levels

2019-05-09

Assessing the causal association of glycine with risk of cardio-metabolic diseases.

Wittemans LBL, Lotta LA et al.

Nat Commun

Glycine levels

2019-03-05

Identification of seven novel loci associated with amino acid levels using single-variant and gene-based tests in 8545 Finnish men from the METSIM study.

Teslovich TM, Kim DS et al.

Hum Mol Genet

Alanine levels

2018-05-01

Genome-wide association study and targeted metabolomics identifies sex-specific association of CPS1 with coronary artery disease.

Hartiala JA, Tang WH et al.

Nat Commun

Betaine levels in individuals undergoing cardiac evaluation

2016-01-29