Active: Hepatitis B Clear all

GWAS 2022-06-13

Genome-Wide Association Study for Chronic Hepatitis B Infection in the Thai Population.

Ashouri S, Khor SS et al.

Front Genet

To identify novel host genetic variants that predispose to hepatitis B virus (HBV) persistence, we p...

Chronic hepatitis B infection

627

Participants

N/A

Studies

Details PubMed

GWAS 2021-03-18

Genome-wide association study identifies new loci associated with risk of HBV infection and disease progression.

Zeng Z, Liu H et al.

BMC Med Genomics

Recent studies have identified susceptibility genes of HBV clearance, chronic hepatitis B, liver cir...

Persistent hepatitis B virus infection

862

Participants

N/A

Studies

Details PubMed

GWAS 2020-06-23

Large-scale genome-wide association study identifies HLA class II variants associated with chronic HBV infection: a study from Taiwan Biobank.

Huang YH, Liao SF et al.

Aliment Pharmacol Ther

Chronic hepatitis B virus (HBV) infection is a great health burden with geographical variations.

Chronic hepatitis B infection

Replicated

14650

Participants

N/A

Studies

Details PubMed

GWAS 2019-06-27

GWAS identifying HLA-DPB1 gene variants associated with responsiveness to hepatitis B virus vaccination in Koreans: Independent association of HLA-DPB1*04:02 possessing rs1042169 G - rs9277355 C - rs9277356 A.

Chung S, Roh EY et al.

J Viral Hepat

Recently, HLA class II loci, including HLA-DPB1, have been reported to be associated with interindiv...

Response to hepatitis B vaccine

Replicated

9477

Participants

N/A

Studies

Details PubMed

GWAS 2019-06-10

Locus 5p13.1 may be associated with the selection of cancer-related HBV core promoter mutations.

Chen QY, Hu YL et al.

Int J Med Sci

The basal core promoter (BCP) double mutations (A1762T and G1764A) of hepatitis B virus (HBV) have b...

Viral basal core promoter double mutation in hepatitis B virus surface antigen (HBsAg) seropositivity

Replicated

793

Participants

N/A

Studies

Details PubMed

GWAS 2019-04-10

Genetic variation in FCER1A predicts peginterferon alfa-2a-induced hepatitis B surface antigen clearance in East Asian patients with chronic hepatitis B.

Wei L, Pavlovic V et al.

J Viral Hepat

In a multicentre, genome-wide association study to identify host genetic factors associated with tre...

Peginterferon alfa-2a treatment response in chronic hepatitis B infection

1636

Participants

N/A

Studies

Details PubMed

GWAS 2019-02-02

Genome Wide Association Study Identifies Genetic Variants Associated With Early And Sustained Response To (Peg)Interferon In Chronic Hepatitis B Patients: The GIANT-B Study.

Brouwer WP, Chan HLY et al.

Clin Infect Dis

(Pegylated) Interferon ([Peg]IFN) therapy leads to response in a minority of chronic hepatitis B (CH...

Response to (pegylated) interferon in HBeAg-negative hepatitis B

414

Participants

N/A

Studies

Details PubMed

GWAS 2018-12-18

Clinical Implication and the Hereditary Factors of NM23 in Hepatocellular Carcinoma Based on Bioinformatics Analysis and Genome-Wide Association Study.

Yang C, Han C et al.

J Oncol

NM23 expression is closely associated with hepatocellular carcinoma (HCC) recurrence, but the heredi...

Nucleoside diphosphate kinase A levels in hepatocellular carcinoma

408

Participants

N/A

Studies

Details PubMed

GWAS 2018-07-05

Identification of novel susceptibility loci associated with hepatitis B surface antigen seroclearance in chronic hepatitis B.

Kim TH, Lee EJ et al.

PLoS One

Background/aims: The seroclearance of hepatitis B virus (HBV) surface antigen (HBsAg) is regarded as...

Hepatitis B surface antigen seroclearance in chronic hepatitis B infection

200

Participants

N/A

Studies

Details PubMed

GWAS 2018-05-21

Genome-wide association study identified new susceptible genetic variants in HLA class I region for hepatitis B virus-related hepatocellular carcinoma.

Sawai H, Nishida N et al.

Sci Rep

We have performed a genome-wide association study (GWAS) including 473 Japanese HBV (hepatitis B vir...

Hepatocellular carcinoma in hepatitis B infection

Replicated

2420

Participants

N/A

Studies

Details PubMed

GWAS 2018-03-13

Key HLA-DRB1-DQB1 haplotypes and role of the BTNL2 gene for response to a hepatitis B vaccine.

Nishida N, Sugiyama M et al.

Hepatology

Approximately 5-10% of individuals who are vaccinated with a hepatitis B (HB) vaccine designed based...

Response to hepatitis B vaccine

1193

Participants

N/A

Studies

Details PubMed

GWAS 2018-02-15

Genome-Wide Association Study Identifies a New Locus at 7q21.13 Associated with Hepatitis B Virus-Related Hepatocellular Carcinoma.

Li Y, Zhai Y et al.

Clin Cancer Res

Purpose: Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide. In China, chron...

Hepatitis B virus-related hepatocellular carcinoma

Replicated

7614

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Genome-Wide Association Study for Chronic Hepatitis B Infection in the Thai Population.

Ashouri S, Khor SS et al.

Front Genet

Chronic hepatitis B infection

2022-06-13

Genome-wide association study identifies new loci associated with risk of HBV infection and disease progression.

Zeng Z, Liu H et al.

BMC Med Genomics

Persistent hepatitis B virus infection

2021-03-18

Large-scale genome-wide association study identifies HLA class II variants associated with chronic HBV infection: a study from Taiwan Biobank.

Huang YH, Liao SF et al.

Aliment Pharmacol Ther

Chronic hepatitis B infection

2020-06-23

GWAS identifying HLA-DPB1 gene variants associated with responsiveness to hepatitis B virus vaccination in Koreans: Independent association of HLA-DPB1*04:02 possessing rs1042169 G - rs9277355 C - rs9277356 A.

Chung S, Roh EY et al.

J Viral Hepat

Response to hepatitis B vaccine

2019-06-27

Locus 5p13.1 may be associated with the selection of cancer-related HBV core promoter mutations.

Chen QY, Hu YL et al.

Int J Med Sci

Viral basal core promoter double mutation in hepatitis B virus surface antigen (HBsAg) seropositivity

2019-06-10

Genetic variation in FCER1A predicts peginterferon alfa-2a-induced hepatitis B surface antigen clearance in East Asian patients with chronic hepatitis B.

Wei L, Pavlovic V et al.

J Viral Hepat

Peginterferon alfa-2a treatment response in chronic hepatitis B infection

2019-04-10

Genome Wide Association Study Identifies Genetic Variants Associated With Early And Sustained Response To (Peg)Interferon In Chronic Hepatitis B Patients: The GIANT-B Study.

Brouwer WP, Chan HLY et al.

Clin Infect Dis

Response to (pegylated) interferon in HBeAg-negative hepatitis B

2019-02-02

Clinical Implication and the Hereditary Factors of NM23 in Hepatocellular Carcinoma Based on Bioinformatics Analysis and Genome-Wide Association Study.

Yang C, Han C et al.

J Oncol

Nucleoside diphosphate kinase A levels in hepatocellular carcinoma

2018-12-18

Identification of novel susceptibility loci associated with hepatitis B surface antigen seroclearance in chronic hepatitis B.

Kim TH, Lee EJ et al.

PLoS One

Hepatitis B surface antigen seroclearance in chronic hepatitis B infection

2018-07-05

Genome-wide association study identified new susceptible genetic variants in HLA class I region for hepatitis B virus-related hepatocellular carcinoma.

Sawai H, Nishida N et al.

Sci Rep

Hepatocellular carcinoma in hepatitis B infection

2018-05-21

Key HLA-DRB1-DQB1 haplotypes and role of the BTNL2 gene for response to a hepatitis B vaccine.

Nishida N, Sugiyama M et al.

Hepatology

Response to hepatitis B vaccine

2018-03-13

Genome-Wide Association Study Identifies a New Locus at 7q21.13 Associated with Hepatitis B Virus-Related Hepatocellular Carcinoma.

Li Y, Zhai Y et al.

Clin Cancer Res

Hepatitis B virus-related hepatocellular carcinoma

2018-02-15