Active: Hypertriglyceridemia Clear all

GWAS 2023-10-02

Apolipoprotein-CIII O-Glycosylation, a Link between GALNT2 and Plasma Lipids.

Naber A, Demus D et al.

Int J Mol Sci

Apolipoprotein-CIII (apo-CIII) is involved in triglyceride-rich lipoprotein metabolism and linked to...

Apo-CIII0c levels

2318

Participants

N/A

Studies

Details PubMed

GWAS 2023-04-26

A Positive Causal Relationship between Noodle Intake and Metabolic Syndrome: A Two-Sample Mendelian Randomization Study.

Park S, Liu M

Nutrients

The controversy over the link between noodle consumption and metabolic syndrome (MetS) persists. Usi...

Noodle intake

58701

Participants

N/A

Studies

Details PubMed

GWAS 2023-01-26

A Causal and Inverse Relationship between Plant-Based Diet Intake and in a Two-Sample Mendelian Randomization Study.

Park S

Foods

A plant-based diet (PBD) has been reported to be linked to metabolic syndrome (MetS) risk in observa...

Highly plant-based diet

58701

Participants

N/A

Studies

Details PubMed

GWAS 2022-04-27

A Causal Relationship between Vitamin C Intake with Hyperglycemia and Metabolic Syndrome Risk: A Two-Sample Mendelian Randomization Study.

Liu M, Park S

Antioxidants (Basel)

Excessive oxidative stress can contribute to metabolic syndrome (MetS), and antioxidants can protect...

Vitamin C intake

52676

Participants

N/A

Studies

Details PubMed

GWAS 2019-05-13

Exome chip-driven association study of lipidemia in >14,000 Koreans and evaluation of genetic effect on identified variants between different ethnic groups.

Han S, Hwang MY et al.

Genet Epidemiol

Lipid levels in blood are widely used to diagnose and monitor chronic diseases. It is essential to i...

LDL cholesterol levels

13890

Participants

N/A

Studies

Details PubMed

GWAS 2016-09-07

A common variant association study in ethnic Saudi Arabs reveals novel susceptibility loci for hypertriglyceridemia.

Ram R, Wakil SM et al.

Clin Genet

Hypertriglyceridemia (hTG) is a lipid disorder, resulting from an elevation in triglyceride levels, ...

Hypertriglyceridemia

Replicated

5501

Participants

N/A

Studies

Details PubMed

GWAS 2016-07-01

A genome-wide study of lipid response to fenofibrate in Caucasians: a combined analysis of the GOLDN and ACCORD studies.

Irvin MR, Rotroff DM et al.

Pharmacogenet Genomics

Fibrates are commonly prescribed for hypertriglyceridemia, but they also lower LDL cholesterol and i...

Response to fenofibrate (HDL cholesterol levels)

Replicated

2082

Participants

N/A

Studies

Details PubMed

GWAS 2013-03-15

Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci.

Weissglas-Volkov D, Aguilar-Salinas CA et al.

J Med Genet

The Mexican population and others with Amerindian heritage exhibit a substantial predisposition to d...

Hypertriglyceridemia

Replicated

4361

Participants

N/A

Studies

Details PubMed

GWAS 2013-02-12

Genome-wide association analyses suggest NELL1 influences adverse metabolic response to HCTZ in African Americans.

Del-Aguila JL, Beitelshees AL et al.

Pharmacogenomics J

Hydrochlorothiazide (HCTZ) is one of the most widely prescribed antihypertensive medications. Althou...

Thiazide-induced adverse metabolic effects in hypertensive patients

767

Participants

N/A

Studies

Details PubMed

GWAS 2012-08-09

Genome-wide association study indicates variants associated with insulin signaling and inflammation mediate lipoprotein responses to fenofibrate.

Frazier-Wood AC, Aslibekyan S et al.

Pharmacogenet Genomics

Objective: A shift towards overall larger very low-density lipoprotein (VLDL), and smaller low-densi...

Response to fenofibrate

817

Participants

N/A

Studies

Details PubMed

GWAS 2010-07-25

Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia.

Johansen CT, Wang J et al.

Nat Genet

Genome-wide association studies (GWAS) have identified multiple loci associated with plasma lipid co...

Hypertriglyceridemia

1660

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Apolipoprotein-CIII O-Glycosylation, a Link between GALNT2 and Plasma Lipids.

Naber A, Demus D et al.

Int J Mol Sci

Apo-CIII0c levels

2023-10-02

A Positive Causal Relationship between Noodle Intake and Metabolic Syndrome: A Two-Sample Mendelian Randomization Study.

Park S, Liu M

Nutrients

Noodle intake

2023-04-26

A Causal and Inverse Relationship between Plant-Based Diet Intake and in a Two-Sample Mendelian Randomization Study.

Park S

Foods

Highly plant-based diet

2023-01-26

A Causal Relationship between Vitamin C Intake with Hyperglycemia and Metabolic Syndrome Risk: A Two-Sample Mendelian Randomization Study.

Liu M, Park S

Antioxidants (Basel)

Vitamin C intake

2022-04-27

Exome chip-driven association study of lipidemia in >14,000 Koreans and evaluation of genetic effect on identified variants between different ethnic groups.

Han S, Hwang MY et al.

Genet Epidemiol

LDL cholesterol levels

2019-05-13

A common variant association study in ethnic Saudi Arabs reveals novel susceptibility loci for hypertriglyceridemia.

Ram R, Wakil SM et al.

Clin Genet

Hypertriglyceridemia

2016-09-07

A genome-wide study of lipid response to fenofibrate in Caucasians: a combined analysis of the GOLDN and ACCORD studies.

Irvin MR, Rotroff DM et al.

Pharmacogenet Genomics

Response to fenofibrate (HDL cholesterol levels)

2016-07-01

Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci.

Weissglas-Volkov D, Aguilar-Salinas CA et al.

J Med Genet

Hypertriglyceridemia

2013-03-15

Genome-wide association analyses suggest NELL1 influences adverse metabolic response to HCTZ in African Americans.

Del-Aguila JL, Beitelshees AL et al.

Pharmacogenomics J

Thiazide-induced adverse metabolic effects in hypertensive patients

2013-02-12

Genome-wide association study indicates variants associated with insulin signaling and inflammation mediate lipoprotein responses to fenofibrate.

Frazier-Wood AC, Aslibekyan S et al.

Pharmacogenet Genomics

Response to fenofibrate

2012-08-09

Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia.

Johansen CT, Wang J et al.

Nat Genet

Hypertriglyceridemia

2010-07-25

Health & Traits Publications

Apolipoprotein-CIII <i>O</i>-Glycosylation, a Link between <i>GALNT2</i> and Plasma Lipids.

A Positive Causal Relationship between Noodle Intake and Metabolic Syndrome: A Two-Sample Mendelian Randomization Study.

A Causal and Inverse Relationship between Plant-Based Diet Intake and in a Two-Sample Mendelian Randomization Study.

A Causal Relationship between Vitamin C Intake with Hyperglycemia and Metabolic Syndrome Risk: A Two-Sample Mendelian Randomization Study.

Exome chip-driven association study of lipidemia in >14,000 Koreans and evaluation of genetic effect on identified variants between different ethnic groups.

A common variant association study in ethnic Saudi Arabs reveals novel susceptibility loci for hypertriglyceridemia.

A genome-wide study of lipid response to fenofibrate in Caucasians: a combined analysis of the GOLDN and ACCORD studies.

Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci.

Genome-wide association analyses suggest NELL1 influences adverse metabolic response to HCTZ in African Americans.

Genome-wide association study indicates variants associated with insulin signaling and inflammation mediate lipoprotein responses to fenofibrate.

Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia.