Active: Insulin resistance/response Clear all

GWAS 2018-09-28

High genetic risk scores of SLIT3, PLEKHA5 and PPP2R2C variants increased insulin resistance and interacted with coffee and caffeine consumption in middle-aged adults.

Daily JW, Liu M et al.

Nutr Metab Cardiovasc Dis

Backgrounds and aims: Insulin resistance is a common feature of metabolic syndrome that may be influ...

Insulin resistance/response

8842

Participants

N/A

Studies

Details PubMed

GWAS 2015-03-23

Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene.

Knowles JW, Xie W et al.

J Clin Invest

Decreased insulin sensitivity, also referred to as insulin resistance (IR), is a fundamental abnorma...

Insulin resistance/response

Replicated

5624

Participants

N/A

Studies

Details PubMed

GWAS 2011-08-25

Genome-wide detection of allele specific copy number variation associated with insulin resistance in African Americans from the HyperGEN study.

Irvin MR, Wineinger NE et al.

PLoS One

African Americans have been understudied in genome wide association studies of diabetes and related ...

Insulin resistance/response

1040

Participants

N/A

Studies

Details PubMed

GWAS 2009-05-09

A genome-wide association scan for acute insulin response to glucose in Hispanic-Americans: the Insulin Resistance Atherosclerosis Family Study (IRAS FS).

Rich SS, Goodarzi MO et al.

Diabetologia

Aims/hypothesis: This study sought to identify genes and regions in the human genome that are associ...

Insulin resistance/response

Replicated

1190

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

High genetic risk scores of SLIT3, PLEKHA5 and PPP2R2C variants increased insulin resistance and interacted with coffee and caffeine consumption in middle-aged adults.

Daily JW, Liu M et al.

Nutr Metab Cardiovasc Dis

Insulin resistance/response

2018-09-28

Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene.

Knowles JW, Xie W et al.

J Clin Invest

Insulin resistance/response

2015-03-23

Genome-wide detection of allele specific copy number variation associated with insulin resistance in African Americans from the HyperGEN study.

Irvin MR, Wineinger NE et al.

PLoS One

Insulin resistance/response

2011-08-25

A genome-wide association scan for acute insulin response to glucose in Hispanic-Americans: the Insulin Resistance Atherosclerosis Family Study (IRAS FS).

Rich SS, Goodarzi MO et al.

Diabetologia

Insulin resistance/response

2009-05-09