Active: Intracranial aneurysm Clear all

GWAS 2025-11-05

Genome-wide Association Studies of over 30,000 Samples with Bone Mineral Density at Multiple Skeletal Sites and Its Clinical Relevance.

Qian Y, Xia J et al.

Genomics Proteomics Bioinformatics

The ultimate goal of a genome-wide association study (GWAS) is to translate its discoveries into cli...

DXA-Bone mineral density (lumbar spine)

30449

Participants

N/A

Studies

Details PubMed

GWAS 2022-07-19

Multinational Genome-Wide Association Study and Functional Genomics Analysis Implicates Decreased SIRT3 Expression Underlying Intracranial Aneurysm Risk.

Hale AT, He J et al.

Neurosurgery

The genetic mechanisms regulating intracranial aneurysm (IA) formation and rupture are largely unkno...

Intracranial aneurysm

155154

Participants

N/A

Studies

Details PubMed

GWAS 2021-10-15

Genetic investigation of fibromuscular dysplasia identifies risk loci and shared genetics with common cardiovascular diseases.

Georges A, Yang ML et al.

Nat Commun

Fibromuscular dysplasia (FMD) is an arteriopathy associated with hypertension, stroke and myocardial...

Fibromuscular dysplasia

8656

Participants

N/A

Studies

Details PubMed

GWAS 2020-11-16

Genome-wide association study of intracranial aneurysms identifies 17 risk loci and genetic overlap with clinical risk factors.

Bakker MK, van der Spek RAA et al.

Nat Genet

Rupture of an intracranial aneurysm leads to subarachnoid hemorrhage, a severe type of stroke. To di...

Intracranial aneurysm

79429

Participants

N/A

Studies

Details PubMed

GWAS 2019-11-15

Exome-chip association analysis of intracranial aneurysms.

van 't Hof FNG, Lai D et al.

Neurology

Objective: To investigate to what extent low-frequency genetic variants (with minor allele frequenci...

Intracranial aneurysm

Replicated

3771

Participants

N/A

Studies

Details PubMed

GWAS 2019-02-25

Genomic Variations in Susceptibility to Intracranial Aneurysm in the Korean Population.

Hong EP, Kim BJ et al.

J Clin Med

Genome-wide association studies found genetic variations with modulatory effects for intracranial an...

Intracranial aneurysm

546

Participants

N/A

Studies

Details PubMed

GWAS 2018-05-29

Identification of nine genes as novel susceptibility loci for early-onset ischemic stroke, intracerebral hemorrhage, or subarachnoid hemorrhage.

Yamada Y, Kato K et al.

Biomed Rep

Given that substantial genetic components have been shown in ischemic stroke, intracerebral hemorrha...

Ischemic stroke

6224

Participants

N/A

Studies

Details PubMed

GWAS 2018-03-12

Genome-wide association analysis identifies new candidate risk loci for familial intracranial aneurysm in the French-Canadian population.

Zhou S, Gan-Or Z et al.

Sci Rep

Intracranial Aneurysm (IA) is a common disease with a worldwide prevalence of 1-3%. In the French-Ca...

Intracranial aneurysm

Replicated

5978

Participants

N/A

Studies

Details PubMed

GWAS 2016-07-14

Shared Genetic Risk Factors of Intracranial, Abdominal, and Thoracic Aneurysms.

van 't Hof FN, Ruigrok YM et al.

J Am Heart Assoc

Intracranial aneurysms (IAs), abdominal aortic aneurysms (AAAs), and thoracic aortic aneurysms (TAAs...

Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy)

12601

Participants

N/A

Studies

Details PubMed

GWAS 2015-07-17

Genetic Variants Underlying Risk of Intracranial Aneurysms: Insights from a GWAS in Portugal.

Abrantes P, Santos MM et al.

PLoS One

Subarachnoid hemorrhage (SAH) is a life-threatening event that most frequently leads to severe disab...

Intracranial aneurysm

Replicated

699

Participants

N/A

Studies

Details PubMed

GWAS 2014-09-25

Genome-wide association study of intracranial aneurysm identifies a new association on chromosome 7.

Foroud T, Lai D et al.

Stroke

Background and purpose: Common variants have been identified using genome-wide association studies w...

Intracranial aneurysm

Replicated

12002

Participants

N/A

Studies

Details PubMed

GWAS 2012-09-06

Genome-wide association study of intracranial aneurysms confirms role of Anril and SOX17 in disease risk.

Foroud T, Koller DL et al.

Stroke

Genomewide association studies have identified novel genetic factors that contribute to intracranial...

Intracranial aneurysm

3166

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Genome-wide Association Studies of over 30,000 Samples with Bone Mineral Density at Multiple Skeletal Sites and Its Clinical Relevance.

Qian Y, Xia J et al.

Genomics Proteomics Bioinformatics

DXA-Bone mineral density (lumbar spine)

2025-11-05

Multinational Genome-Wide Association Study and Functional Genomics Analysis Implicates Decreased SIRT3 Expression Underlying Intracranial Aneurysm Risk.

Hale AT, He J et al.

Neurosurgery

Intracranial aneurysm

2022-07-19

Genetic investigation of fibromuscular dysplasia identifies risk loci and shared genetics with common cardiovascular diseases.

Georges A, Yang ML et al.

Nat Commun

Fibromuscular dysplasia

2021-10-15

Genome-wide association study of intracranial aneurysms identifies 17 risk loci and genetic overlap with clinical risk factors.

Bakker MK, van der Spek RAA et al.

Nat Genet

Intracranial aneurysm

2020-11-16

Exome-chip association analysis of intracranial aneurysms.

van 't Hof FNG, Lai D et al.

Neurology

Intracranial aneurysm

2019-11-15

Genomic Variations in Susceptibility to Intracranial Aneurysm in the Korean Population.

Hong EP, Kim BJ et al.

J Clin Med

Intracranial aneurysm

2019-02-25

Identification of nine genes as novel susceptibility loci for early-onset ischemic stroke, intracerebral hemorrhage, or subarachnoid hemorrhage.

Yamada Y, Kato K et al.

Biomed Rep

Ischemic stroke

2018-05-29

Genome-wide association analysis identifies new candidate risk loci for familial intracranial aneurysm in the French-Canadian population.

Zhou S, Gan-Or Z et al.

Sci Rep

Intracranial aneurysm

2018-03-12

Shared Genetic Risk Factors of Intracranial, Abdominal, and Thoracic Aneurysms.

van 't Hof FN, Ruigrok YM et al.

J Am Heart Assoc

Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy)

2016-07-14

Genetic Variants Underlying Risk of Intracranial Aneurysms: Insights from a GWAS in Portugal.

Abrantes P, Santos MM et al.

PLoS One

Intracranial aneurysm

2015-07-17

Genome-wide association study of intracranial aneurysm identifies a new association on chromosome 7.

Foroud T, Lai D et al.

Stroke

Intracranial aneurysm

2014-09-25

Genome-wide association study of intracranial aneurysms confirms role of Anril and SOX17 in disease risk.

Foroud T, Koller DL et al.

Stroke

Intracranial aneurysm

2012-09-06