Active: Iron status biomarkers Clear all

GWAS 2021-02-03

A genome-wide meta-analysis yields 46 new loci associating with biomarkers of iron homeostasis.

Bell S, Rigas AS et al.

Commun Biol

Iron is essential for many biological functions and iron deficiency and overload have major health i...

Iron status biomarkers (ferritin levels)

246139

Participants

N/A

Studies

Details PubMed

GWAS 2017-05-15

Genome-wide association study of iron traits and relation to diabetes in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL): potential genomic intersection of iron and glucose regulation?

Raffield LM, Louie T et al.

Hum Mol Genet

Genetic variants contribute to normal variation of iron-related traits and may also cause clinical s...

Iron status biomarkers (ferritin levels)

12375

Participants

N/A

Studies

Details PubMed

GWAS 2014-10-29

Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis.

Benyamin B, Esko T et al.

Nat Commun

Variation in body iron is associated with or causes diseases, including anaemia and iron overload. H...

Iron status biomarkers (ferritin levels)

Replicated

48972

Participants

N/A

Studies

Details PubMed

GWAS 2014-09-15

Genome-wide admixture and association study of serum iron, ferritin, transferrin saturation and total iron binding capacity in African Americans.

Li J, Lange LA et al.

Hum Mol Genet

Iron is an essential component of many important proteins and enzymes, including hemoglobin, which i...

Iron status biomarkers

Replicated

2676

Participants

N/A

Studies

Details PubMed

GWAS 2011-03-31

Genome-wide association study identifies genetic loci associated with iron deficiency.

McLaren CE, Garner CP et al.

PLoS One

The existence of multiple inherited disorders of iron metabolism in man, rodents and other vertebrat...

Iron status biomarkers

Replicated

911

Participants

N/A

Studies

Details PubMed

GWAS 2011-01-04

Identification of a common variant in the TFR2 gene implicated in the physiological regulation of serum iron levels.

Pichler I, Minelli C et al.

Hum Mol Genet

The genetic determinants of variation in iron status are actively sought, but remain incompletely un...

Iron status biomarkers

Replicated

9090

Participants

N/A

Studies

Details PubMed

GWAS 2010-12-10

Novel association to the proprotein convertase PCSK7 gene locus revealed by analysing soluble transferrin receptor (sTfR) levels.

Oexle K, Ried JS et al.

Hum Mol Genet

The level of body iron storage and the erythropoietic need for iron are indicated by the serum level...

Iron status biomarkers

6616

Participants

N/A

Studies

Details PubMed

GWAS 2009-10-11

Common variants in TMPRSS6 are associated with iron status and erythrocyte volume.

Benyamin B, Ferreira MA et al.

Nat Genet

We report a genome-wide association study to iron status. We identify an association of SNPs in TPMR...

Iron status biomarkers

Replicated

8288

Participants

N/A

Studies

Details PubMed

GWAS 2008-12-17

Variants in TF and HFE explain approximately 40% of genetic variation in serum-transferrin levels.

Benyamin B, McRae AF et al.

Am J Hum Genet

Only a small proportion of genetic variation in complex traits has been explained by SNPs from genom...

Iron status biomarkers

411

Participants

N/A

Studies

Details PubMed

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A genome-wide meta-analysis yields 46 new loci associating with biomarkers of iron homeostasis.

Bell S, Rigas AS et al.

Commun Biol

Iron status biomarkers (ferritin levels)

2021-02-03

Genome-wide association study of iron traits and relation to diabetes in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL): potential genomic intersection of iron and glucose regulation?

Raffield LM, Louie T et al.

Hum Mol Genet

Iron status biomarkers (ferritin levels)

2017-05-15

Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis.

Benyamin B, Esko T et al.

Nat Commun

Iron status biomarkers (ferritin levels)

2014-10-29

Genome-wide admixture and association study of serum iron, ferritin, transferrin saturation and total iron binding capacity in African Americans.

Li J, Lange LA et al.

Hum Mol Genet

Iron status biomarkers

2014-09-15

Genome-wide association study identifies genetic loci associated with iron deficiency.

McLaren CE, Garner CP et al.

PLoS One

Iron status biomarkers

2011-03-31

Identification of a common variant in the TFR2 gene implicated in the physiological regulation of serum iron levels.

Pichler I, Minelli C et al.

Hum Mol Genet

Iron status biomarkers

2011-01-04

Novel association to the proprotein convertase PCSK7 gene locus revealed by analysing soluble transferrin receptor (sTfR) levels.

Oexle K, Ried JS et al.

Hum Mol Genet

Iron status biomarkers

2010-12-10

Common variants in TMPRSS6 are associated with iron status and erythrocyte volume.

Benyamin B, Ferreira MA et al.

Nat Genet

Iron status biomarkers

2009-10-11

Variants in TF and HFE explain approximately 40% of genetic variation in serum-transferrin levels.

Benyamin B, McRae AF et al.

Am J Hum Genet

Iron status biomarkers

2008-12-17