Active: Lean body mass Clear all

GWAS 2022-08-02

Association of sedentary and physical activity behaviours with body composition: a genome-wide association and Mendelian randomisation study.

Ramadan FA, Bea JW et al.

BMJ Open Sport Exerc Med

Objectives: Studies suggest that body composition can be independently improved through physical act...

Moderate physical activity

360911

Participants

N/A

Studies

Details PubMed

GWAS 2022-03-03

Unveiling genetic variants for age-related sarcopenia by conducting a genome-wide association study on Korean cohorts.

Jin H, Yoo HJ et al.

Sci Rep

Sarcopenia is an age-related disorder characterised by a progressive decrease in skeletal muscle mas...

Body fat mass

6961

Participants

N/A

Studies

Details PubMed

GWAS 2020-09-24

Three pleiotropic loci associated with bone mineral density and lean body mass.

Zhang YX, Zhang SS et al.

Mol Genet Genomics

Both bone mineral density (BMD) and lean body mass (LBM) are important physiological measures with s...

Bone mineral density or leg lean mass (pleiotropy)

Replicated

512445

Participants

N/A

Studies

Details PubMed

GWAS 2020-09-14

Identification of pleiotropic loci underlying hip bone mineral density and trunk lean mass.

Feng GJ, Wei XT et al.

J Hum Genet

Bone mineral density (BMD) and lean body mass (LBM) not only have a considerable heritability each, ...

Bone mineral density or trunk lean mass (pleiotropy)

Replicated

226569

Participants

N/A

Studies

Details PubMed

GWAS 2020-03-09

Association of 3p27.1 Variants with Whole Body Lean Mass Identified by a Genome-wide Association Study.

Ran S, Zhang YX et al.

Sci Rep

Whole body lean mass (WBLM) is a heritable trait predicting sarcopenia. To identify genomic locus un...

Lean body mass

Replicated

8211

Participants

N/A

Studies

Details PubMed

GWAS 2017-07-19

Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.

Zillikens MC, Demissie S et al.

Nat Commun

Lean body mass, consisting mostly of skeletal muscle, is important for healthy aging. We performed a...

Appendicular lean mass

Replicated

73420

Participants

N/A

Studies

Details PubMed

GWAS 2017-03-21

Gene-based genome-wide association study identified 19p13.3 for lean body mass.

Ran S, Zhang L et al.

Sci Rep

Lean body mass (LBM) is a complex trait for human health. To identify genomic loci underlying LBM, w...

Lean body mass

Replicated

3283

Participants

N/A

Studies

Details PubMed

GWAS 2014-05-23

Large-scale analysis reveals a functional single-nucleotide polymorphism in the 5'-flanking region of PRDM16 gene associated with lean body mass.

Urano T, Shiraki M et al.

Aging Cell

Genetic factors are important for the development of sarcopenia, a geriatric disorder characterized ...

Lean body mass

Replicated

1350

Participants

N/A

Studies

Details PubMed

GWAS 2013-10-08

Meta-analysis of genome-wide association data identifies novel susceptibility loci for obesity.

Pei YF, Zhang L et al.

Hum Mol Genet

Obesity is a major public health problem with strong genetic determination. Multiple genetic variant...

Body mass index

Replicated

28632

Participants

N/A

Studies

Details PubMed

GWAS 2013-04-10

The chromosome 3q25 genomic region is associated with measures of adiposity in newborns in a multi-ethnic genome-wide association study.

Urbanek M, Hayes MG et al.

Hum Mol Genet

Newborns characterized as large and small for gestational age are at risk for increased mortality an...

Anthropometric traits in newborns

Replicated

6577

Participants

N/A

Studies

Details PubMed

GWAS 2012-06-29

Bivariate genome-wide association study suggests that the DARC gene influences lean body mass and age at menarche.

Hai R, Zhang L et al.

Sci China Life Sci

Lean body mass (LBM) and age at menarche (AAM) are two important complex traits for human health. Th...

Lean body mass and age at menarche (combined)

Replicated

2493

Participants

N/A

Studies

Details PubMed

GWAS 2009-03-04

Genome-wide association and replication studies identified TRHR as an important gene for lean body mass.

Liu XG, Tan LJ et al.

Am J Hum Genet

Low lean body mass (LBM) is related to a series of health problems, such as osteoporotic fracture an...

Body mass (lean)

Replicated

7388

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Association of sedentary and physical activity behaviours with body composition: a genome-wide association and Mendelian randomisation study.

Ramadan FA, Bea JW et al.

BMJ Open Sport Exerc Med

Moderate physical activity

2022-08-02

Unveiling genetic variants for age-related sarcopenia by conducting a genome-wide association study on Korean cohorts.

Jin H, Yoo HJ et al.

Sci Rep

Body fat mass

2022-03-03

Three pleiotropic loci associated with bone mineral density and lean body mass.

Zhang YX, Zhang SS et al.

Mol Genet Genomics

Bone mineral density or leg lean mass (pleiotropy)

2020-09-24

Identification of pleiotropic loci underlying hip bone mineral density and trunk lean mass.

Feng GJ, Wei XT et al.

J Hum Genet

Bone mineral density or trunk lean mass (pleiotropy)

2020-09-14

Association of 3p27.1 Variants with Whole Body Lean Mass Identified by a Genome-wide Association Study.

Ran S, Zhang YX et al.

Sci Rep

Lean body mass

2020-03-09

Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.

Zillikens MC, Demissie S et al.

Nat Commun

Appendicular lean mass

2017-07-19

Gene-based genome-wide association study identified 19p13.3 for lean body mass.

Ran S, Zhang L et al.

Sci Rep

Lean body mass

2017-03-21

Large-scale analysis reveals a functional single-nucleotide polymorphism in the 5'-flanking region of PRDM16 gene associated with lean body mass.

Urano T, Shiraki M et al.

Aging Cell

Lean body mass

2014-05-23

Meta-analysis of genome-wide association data identifies novel susceptibility loci for obesity.

Pei YF, Zhang L et al.

Hum Mol Genet

Body mass index

2013-10-08

The chromosome 3q25 genomic region is associated with measures of adiposity in newborns in a multi-ethnic genome-wide association study.

Urbanek M, Hayes MG et al.

Hum Mol Genet

Anthropometric traits in newborns

2013-04-10

Bivariate genome-wide association study suggests that the DARC gene influences lean body mass and age at menarche.

Hai R, Zhang L et al.

Sci China Life Sci

Lean body mass and age at menarche (combined)

2012-06-29

Genome-wide association and replication studies identified TRHR as an important gene for lean body mass.

Liu XG, Tan LJ et al.

Am J Hum Genet

Body mass (lean)

2009-03-04