Active: Leukocyte telomere length Clear all

GWAS 2024-07-03

SCARF2 is a target for chronic obstructive pulmonary disease: Evidence from multi-omics research and cohort validation.

Wang S, Yue Y et al.

Aging Cell

Age-related chronic inflammatory lung diseases impose a threat on public health, including idiopathi...

Idiopathic pulmonary fibrosis

744812

Participants

N/A

Studies

Details PubMed

GWAS 2024-06-05

Whole exome sequencing analyses reveal novel genes in telomere length and their biomedical implications.

Liu WS, Wu BS et al.

Geroscience

Telomere length is a putative biomarker of aging and is associated with multiple age-related disease...

Leukocyte telomere length

327790

Participants

N/A

Studies

Details PubMed

GWAS 2024-05-10

Causal association and shared genetics between telomere length and COVID-19 outcomes: New evidence from the latest large-scale summary statistics.

Zhang J, Wen J et al.

Comput Struct Biotechnol J

Observational studies suggested that leukocyte telomere length (LTL) is shortened in COVID-19 patien...

Leukocyte telomere length or COVID-19 infection (MTAG)

3070030

Participants

N/A

Studies

Details PubMed

GWAS 2023-04-27

Genetic and clinical determinants of telomere length.

Allaire P, He J et al.

HGG Adv

Many epidemiologic studies have identified important relationships between leukocyte telomere length...

Leukocyte telomere length

62271

Participants

N/A

Studies

Details PubMed

GWAS 2022-07-14

Genome-wide analyses of 200,453 individuals yield new insights into the causes and consequences of clonal hematopoiesis.

Kar SP, Quiros PM et al.

Nat Genet

Clonal hematopoiesis (CH), the clonal expansion of a blood stem cell and its progeny driven by somat...

Clonal hematopoiesis (overall)

Replicated

405406

Participants

N/A

Studies

Details PubMed

GWAS 2021-10-27

Investigating the Role of Leukocyte Telomere Length in Treatment-Resistant Depression and in Response to Electroconvulsive Therapy.

Pisanu C, Vitali E et al.

J Pers Med

Psychiatric disorders seem to be characterized by premature cell senescence. However, controversial ...

Leukocyte telomere length in electroconvulsive therapy treatment-resistant depression

107

Participants

N/A

Studies

Details PubMed

GWAS 2021-05-03

Low frequency variants associated with leukocyte telomere length in the Singapore Chinese population.

Chang X, Gurung RL et al.

Commun Biol

The role of low frequency variants associated with telomere length homeostasis in chronic diseases a...

Telomere length

Replicated

25473

Participants

N/A

Studies

Details PubMed

GWAS 2020-11-13

Telomere length and risk of idiopathic pulmonary fibrosis and chronic obstructive pulmonary disease: a mendelian randomisation study.

Duckworth A, Gibbons MA et al.

Lancet Respir Med

Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease accounting for 1% of UK deaths. In the f...

Idiopathic pulmonary fibrosis

451025

Participants

N/A

Studies

Details PubMed

GWAS 2020-10-30

Effect of plasma polyunsaturated fatty acid levels on leukocyte telomere lengths in the Singaporean Chinese population.

Chang X, Dorajoo R et al.

Nutr J

Shorter telomere length (TL) has been associated with poor health behaviors, increased risks of chro...

Telomere length x n-3 polyunsaturated fatty acid level interaction

1349

Participants

N/A

Studies

Details PubMed

GWAS 2020-02-20

Genome-Wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length.

Li C, Stoma S et al.

Am J Hum Genet

Leukocyte telomere length (LTL) is a heritable biomarker of genomic aging. In this study, we perform...

Leukocyte telomere length

78592

Participants

N/A

Studies

Details PubMed

GWAS 2019-06-06

Loci for human leukocyte telomere length in the Singaporean Chinese population and trans-ethnic genetic studies.

Dorajoo R, Chang X et al.

Nat Commun

Genetic factors underlying leukocyte telomere length (LTL) may provide insights into telomere homeos...

Leukocyte telomere length

Replicated

60601

Participants

N/A

Studies

Details PubMed

GWAS 2018-01-26

GWAS of epigenetic aging rates in blood reveals a critical role for TERT.

Lu AT, Xue L et al.

Nat Commun

DNA methylation age is an accurate biomarker of chronological age and predicts lifespan, but its und...

Extrinsic epigenetic age acceleration

Replicated

9907

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

SCARF2 is a target for chronic obstructive pulmonary disease: Evidence from multi-omics research and cohort validation.

Wang S, Yue Y et al.

Aging Cell

Idiopathic pulmonary fibrosis

2024-07-03

Whole exome sequencing analyses reveal novel genes in telomere length and their biomedical implications.

Liu WS, Wu BS et al.

Geroscience

Leukocyte telomere length

2024-06-05

Causal association and shared genetics between telomere length and COVID-19 outcomes: New evidence from the latest large-scale summary statistics.

Zhang J, Wen J et al.

Comput Struct Biotechnol J

Leukocyte telomere length or COVID-19 infection (MTAG)

2024-05-10

Genetic and clinical determinants of telomere length.

Allaire P, He J et al.

HGG Adv

Leukocyte telomere length

2023-04-27

Genome-wide analyses of 200,453 individuals yield new insights into the causes and consequences of clonal hematopoiesis.

Kar SP, Quiros PM et al.

Nat Genet

Clonal hematopoiesis (overall)

2022-07-14

Investigating the Role of Leukocyte Telomere Length in Treatment-Resistant Depression and in Response to Electroconvulsive Therapy.

Pisanu C, Vitali E et al.

J Pers Med

Leukocyte telomere length in electroconvulsive therapy treatment-resistant depression

2021-10-27

Low frequency variants associated with leukocyte telomere length in the Singapore Chinese population.

Chang X, Gurung RL et al.

Commun Biol

Telomere length

2021-05-03

Telomere length and risk of idiopathic pulmonary fibrosis and chronic obstructive pulmonary disease: a mendelian randomisation study.

Duckworth A, Gibbons MA et al.

Lancet Respir Med

Idiopathic pulmonary fibrosis

2020-11-13

Effect of plasma polyunsaturated fatty acid levels on leukocyte telomere lengths in the Singaporean Chinese population.

Chang X, Dorajoo R et al.

Nutr J

Telomere length x n-3 polyunsaturated fatty acid level interaction

2020-10-30

Genome-Wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length.

Li C, Stoma S et al.

Am J Hum Genet

Leukocyte telomere length

2020-02-20

Loci for human leukocyte telomere length in the Singaporean Chinese population and trans-ethnic genetic studies.

Dorajoo R, Chang X et al.

Nat Commun

Leukocyte telomere length

2019-06-06

GWAS of epigenetic aging rates in blood reveals a critical role for TERT.

Lu AT, Xue L et al.

Nat Commun

Extrinsic epigenetic age acceleration

2018-01-26