Active: Menopause (age at onset) Clear all

GWAS 2018-05-17

Elucidating the genetic architecture of reproductive ageing in the Japanese population.

Horikoshi M, Day FR et al.

Nat Commun

Population studies elucidating the genetic architecture of reproductive ageing have been largely lim...

Menopause (age at onset)

Replicated

76406

Participants

N/A

Studies

Details PubMed

GWAS 2015-11-01

Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair.

Day FR, Ruth KS et al.

Nat Genet

Menopause timing has a substantial impact on infertility and risk of disease, including breast cance...

Menopause (age at onset)

Replicated

69626

Participants

N/A

Studies

Details PubMed

GWAS 2013-09-16

Genome-wide association studies and epistasis analyses of candidate genes related to age at menarche and age at natural menopause in a Korean population.

Pyun JA, Kim S et al.

Menopause

Objective: The aim of this study was to identify polymorphisms and gene-gene interactions that are s...

Menopause (age at onset)

1827

Participants

N/A

Studies

Details PubMed

GWAS 2013-04-16

Shared genetic factors for age at natural menopause in Iranian and European women.

Rahmani M, Earp MA et al.

Hum Reprod

Study question: Do differences in heritable genetic factors explain some of the difference in age at...

Menopause (age at onset)

Replicated

39893

Participants

N/A

Studies

Details PubMed

GWAS 2013-01-09

A genome-wide association study of early menopause and the combined impact of identified variants.

Perry JR, Corre T et al.

Hum Mol Genet

Early menopause (EM) affects up to 10% of the female population, reducing reproductive lifespan cons...

Menopause (age at onset)

Replicated

25431

Participants

N/A

Studies

Details PubMed

GWAS 2012-01-22

Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways.

Stolk L, Perry JR et al.

Nat Genet

To newly identify loci for age at natural menopause, we carried out a meta-analysis of 22 genome-wid...

Menopause (age at onset)

Replicated

53403

Participants

N/A

Studies

Details PubMed

GWAS 2011-11-30

Replication of loci influencing ages at menarche and menopause in Hispanic women: the Women's Health Initiative SHARe Study.

Chen CT, Fernández-Rhodes L et al.

Hum Mol Genet

Several genome-wide studies have identified loci associated with reproductive traits, such as ages o...

Menarche and menopause (age at onset)

3468

Participants

N/A

Studies

Details PubMed

GWAS 2009-05-17

Genome-wide association studies identify loci associated with age at menarche and age at natural menopause.

He C, Kraft P et al.

Nat Genet

Age at menarche and age at natural menopause are associated with causes of substantial morbidity and...

Menarche and menopause (age at onset)

17438

Participants

N/A

Studies

Details PubMed

GWAS 2009-05-15

Loci at chromosomes 13, 19 and 20 influence age at natural menopause.

Stolk L, Zhai G et al.

Nat Genet

We conducted a genome-wide association study for age at natural menopause in 2,979 European women an...

Menopause (age at onset)

Replicated

5539

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Elucidating the genetic architecture of reproductive ageing in the Japanese population.

Horikoshi M, Day FR et al.

Nat Commun

Menopause (age at onset)

2018-05-17

Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair.

Day FR, Ruth KS et al.

Nat Genet

Menopause (age at onset)

2015-11-01

Genome-wide association studies and epistasis analyses of candidate genes related to age at menarche and age at natural menopause in a Korean population.

Pyun JA, Kim S et al.

Menopause

Menopause (age at onset)

2013-09-16

Shared genetic factors for age at natural menopause in Iranian and European women.

Rahmani M, Earp MA et al.

Hum Reprod

Menopause (age at onset)

2013-04-16

A genome-wide association study of early menopause and the combined impact of identified variants.

Perry JR, Corre T et al.

Hum Mol Genet

Menopause (age at onset)

2013-01-09

Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways.

Stolk L, Perry JR et al.

Nat Genet

Menopause (age at onset)

2012-01-22

Replication of loci influencing ages at menarche and menopause in Hispanic women: the Women's Health Initiative SHARe Study.

Chen CT, Fernández-Rhodes L et al.

Hum Mol Genet

Menarche and menopause (age at onset)

2011-11-30

Genome-wide association studies identify loci associated with age at menarche and age at natural menopause.

He C, Kraft P et al.

Nat Genet

Menarche and menopause (age at onset)

2009-05-17

Loci at chromosomes 13, 19 and 20 influence age at natural menopause.

Stolk L, Zhai G et al.

Nat Genet

Menopause (age at onset)

2009-05-15