Active: Mental disorder Clear all

GWAS 2025-06-13

Beyond volume: Unraveling the genetics of human brain geometry.

Primus SA, Hoffstaedter F et al.

Sci Adv

Brain geometry affects brain function. A quantitative encoding of form is provided by the Laplace-Be...

Left accumbens area shape (Laplace-Beltrami spectrum)

Replicated

24823

Participants

N/A

Studies

Details PubMed

GWAS 2025-03-01

Exome sequencing identifies novel genes associated with cerebellar volume and microstructure.

Liang Y, Ma D et al.

Commun Biol

Proteins encoded by exons are critical for cellular functions, and mutations in these genes often re...

Superior cerebellar peduncle fractional anisotropy

35412

Participants

N/A

Studies

Details PubMed

GWAS 2024-11-19

Refining antipsychotic treatment strategies in schizophrenia: discovery of genetic biomarkers for enhanced drug response prediction.

Chen L, Huai C et al.

Mol Psychiatry

Schizophrenia (SCZ) is a severe mental disorder affecting around 1% of individuals worldwide. The va...

Response to antipsychotic treatment in schizophrenia

2114

Participants

N/A

Studies

Details PubMed

GWAS 2024-06-11

Shared genetic effect of kidney function on bipolar and major depressive disorders: a large-scale genome-wide cross-trait analysis.

Yu S, Lin Y et al.

Hum Genomics

Epidemiological studies have revealed a significant association between impaired kidney function and...

Bipolar disorder or blood urea nitrogen levels (MTAG)

904388

Participants

N/A

Studies

Details PubMed

GWAS 2023-12-13

The correlates of neonatal complement component 3 and 4 protein concentrations with a focus on psychiatric and autoimmune disorders.

Borbye-Lorenzen N, Zhu Z et al.

Cell Genom

Complement components have been linked to schizophrenia and autoimmune disorders. We examined the as...

Neonatal circulating Complement Component 3 (C3) protein concentration

68768

Participants

N/A

Studies

Details PubMed

GWAS 2023-12-08

A multidimensional social risk atlas of depression and anxiety: An observational and genome-wide environmental interaction study.

Pan C, Liu L et al.

J Glob Health

Mental disorders are largely socially determined, yet the combined impact of multidimensional social...

PHQ score x Polysocial risk score (PsRS) interaction

Replicated

110334

Participants

N/A

Studies

Details PubMed

GWAS 2023-11-09

Genome-wide meta-analysis, functional genomics and integrative analyses implicate new risk genes and therapeutic targets for anxiety disorders.

Li W, Chen R et al.

Nat Hum Behav

Anxiety disorders are the most prevalent mental disorders. However, the genetic etiology of anxiety ...

Anxiety disorder

475216

Participants

N/A

Studies

Details PubMed

GWAS 2023-02-02

Genome-wide Association Study points to novel locus for Gilles de la Tourette Syndrome.

Tsetsos F, Topaloudi A et al.

Biol Psychiatry

Tourette syndrome (TS) is a childhood-onset neurodevelopmental disorder of complex genetic architect...

Tourette syndrome

19698

Participants

N/A

Studies

Details PubMed

GWAS 2023-01-26

Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains.

Demontis D, Walters GB et al.

Nat Genet

Attention-deficit hyperactivity disorder (ADHD) is a prevalent neurodevelopmental disorder with a ma...

Attention deficit hyperactivity disorder

225534

Participants

N/A

Studies

Details PubMed

GWAS 2023-01-04

GWAS of depression in 4,520 individuals from the Russian population highlights the role of MAGI2 (S-SCAM) in the gut-brain axis.

Pinakhina D, Yermakovich D et al.

Front Genet

We present the results of the depression Genome-wide association studies study performed on a cohort...

Depression

4520

Participants

N/A

Studies

Details PubMed

GWAS 2022-12-23

The first genome-wide association study of internet addiction; Revealed substantial shared risk factors with neurodevelopmental psychiatric disorders.

Haghighatfard A, Ghaderi AH et al.

Res Dev Disabil

Internet addiction disorder (IAD) is listed as a disorder requiring further studies in the diagnosti...

Internet addiction disorder

34520

Participants

N/A

Studies

Details PubMed

GWAS 2022-11-15

Meta-analysis of genome-wide association studies of hoarding symptoms in 27,537 individuals.

Strom NI, Smit DJA et al.

Transl Psychiatry

Hoarding Disorder (HD) is a mental disorder characterized by persistent difficulties discarding or p...

Hoarding symptoms

27537

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Beyond volume: Unraveling the genetics of human brain geometry.

Primus SA, Hoffstaedter F et al.

Sci Adv

Left accumbens area shape (Laplace-Beltrami spectrum)

2025-06-13

Exome sequencing identifies novel genes associated with cerebellar volume and microstructure.

Liang Y, Ma D et al.

Commun Biol

Superior cerebellar peduncle fractional anisotropy

2025-03-01

Refining antipsychotic treatment strategies in schizophrenia: discovery of genetic biomarkers for enhanced drug response prediction.

Chen L, Huai C et al.

Mol Psychiatry

Response to antipsychotic treatment in schizophrenia

2024-11-19

Shared genetic effect of kidney function on bipolar and major depressive disorders: a large-scale genome-wide cross-trait analysis.

Yu S, Lin Y et al.

Hum Genomics

Bipolar disorder or blood urea nitrogen levels (MTAG)

2024-06-11

The correlates of neonatal complement component 3 and 4 protein concentrations with a focus on psychiatric and autoimmune disorders.

Borbye-Lorenzen N, Zhu Z et al.

Cell Genom

Neonatal circulating Complement Component 3 (C3) protein concentration

2023-12-13

A multidimensional social risk atlas of depression and anxiety: An observational and genome-wide environmental interaction study.

Pan C, Liu L et al.

J Glob Health

PHQ score x Polysocial risk score (PsRS) interaction

2023-12-08

Genome-wide meta-analysis, functional genomics and integrative analyses implicate new risk genes and therapeutic targets for anxiety disorders.

Li W, Chen R et al.

Nat Hum Behav

Anxiety disorder

2023-11-09

Genome-wide Association Study points to novel locus for Gilles de la Tourette Syndrome.

Tsetsos F, Topaloudi A et al.

Biol Psychiatry

Tourette syndrome

2023-02-02

Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains.

Demontis D, Walters GB et al.

Nat Genet

Attention deficit hyperactivity disorder

2023-01-26

GWAS of depression in 4,520 individuals from the Russian population highlights the role of MAGI2 (S-SCAM) in the gut-brain axis.

Pinakhina D, Yermakovich D et al.

Front Genet

Depression

2023-01-04

The first genome-wide association study of internet addiction; Revealed substantial shared risk factors with neurodevelopmental psychiatric disorders.

Haghighatfard A, Ghaderi AH et al.

Res Dev Disabil

Internet addiction disorder

2022-12-23

Meta-analysis of genome-wide association studies of hoarding symptoms in 27,537 individuals.

Strom NI, Smit DJA et al.

Transl Psychiatry

Hoarding symptoms

2022-11-15

Health & Traits Publications

Beyond volume: Unraveling the genetics of human brain geometry.

Exome sequencing identifies novel genes associated with cerebellar volume and microstructure.

Refining antipsychotic treatment strategies in schizophrenia: discovery of genetic biomarkers for enhanced drug response prediction.

Shared genetic effect of kidney function on bipolar and major depressive disorders: a large-scale genome-wide cross-trait analysis.

The correlates of neonatal complement component 3 and 4 protein concentrations with a focus on psychiatric and autoimmune disorders.

A multidimensional social risk atlas of depression and anxiety: An observational and genome-wide environmental interaction study.

Genome-wide meta-analysis, functional genomics and integrative analyses implicate new risk genes and therapeutic targets for anxiety disorders.

Genome-wide Association Study points to novel locus for Gilles de la Tourette Syndrome.

Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains.

GWAS of depression in 4,520 individuals from the Russian population highlights the role of <i>MAGI2</i> (<i>S-SCAM</i>) in the gut-brain axis.

The first genome-wide association study of internet addiction; Revealed substantial shared risk factors with neurodevelopmental psychiatric disorders.

Meta-analysis of genome-wide association studies of hoarding symptoms in 27,537 individuals.