Active: Reproductive lifespan Clear all

GWAS 2023-03-02

Genome-wide analysis identifies genetic effects on reproductive success and ongoing natural selection at the FADS locus.

Mathieson I, Day FR et al.

Nat Hum Behav

Identifying genetic determinants of reproductive success may highlight mechanisms underlying fertili...

Number of children ever born

Replicated

819971

Participants

N/A

Studies

Details PubMed

GWAS 2022-04-12

Interaction between cigarette smoking and genetic polymorphisms on the associations with age of natural menopause and reproductive lifespan: the Singapore Chinese Health Study.

Huang Z

Hum Reprod

Reproductive lifespan

Replicated

11643

Participants

N/A

Studies

Details PubMed

GWAS 2019-01-14

Genome-wide association study of anti-Müllerian hormone levels in pre-menopausal women of late reproductive age and relationship with genetic determinants of reproductive lifespan.

Ruth KS, Soares ALG et al.

Hum Mol Genet

Anti-Müllerian hormone (AMH) is required for sexual differentiation in the fetus, and in adult femal...

Anti-Mullerian hormone levels in pre-menopausal women of late reproductive age

3344

Participants

N/A

Studies

Details PubMed

GWAS 2015-11-01

Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair.

Day FR, Ruth KS et al.

Nat Genet

Menopause timing has a substantial impact on infertility and risk of disease, including breast cance...

Menopause (age at onset)

Replicated

69626

Participants

N/A

Studies

Details PubMed

GWAS 2013-01-09

A genome-wide association study of early menopause and the combined impact of identified variants.

Perry JR, Corre T et al.

Hum Mol Genet

Early menopause (EM) affects up to 10% of the female population, reducing reproductive lifespan cons...

Menopause (age at onset)

Replicated

25431

Participants

N/A

Studies

Details PubMed

GWAS 2011-11-30

Replication of loci influencing ages at menarche and menopause in Hispanic women: the Women's Health Initiative SHARe Study.

Chen CT, Fernández-Rhodes L et al.

Hum Mol Genet

Several genome-wide studies have identified loci associated with reproductive traits, such as ages o...

Menarche and menopause (age at onset)

3468

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Genome-wide analysis identifies genetic effects on reproductive success and ongoing natural selection at the FADS locus.

Mathieson I, Day FR et al.

Nat Hum Behav

Number of children ever born

2023-03-02

Interaction between cigarette smoking and genetic polymorphisms on the associations with age of natural menopause and reproductive lifespan: the Singapore Chinese Health Study.

Huang Z

Hum Reprod

Reproductive lifespan

2022-04-12

Genome-wide association study of anti-Müllerian hormone levels in pre-menopausal women of late reproductive age and relationship with genetic determinants of reproductive lifespan.

Ruth KS, Soares ALG et al.

Hum Mol Genet

Anti-Mullerian hormone levels in pre-menopausal women of late reproductive age

2019-01-14

Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair.

Day FR, Ruth KS et al.

Nat Genet

Menopause (age at onset)

2015-11-01

A genome-wide association study of early menopause and the combined impact of identified variants.

Perry JR, Corre T et al.

Hum Mol Genet

Menopause (age at onset)

2013-01-09

Replication of loci influencing ages at menarche and menopause in Hispanic women: the Women's Health Initiative SHARe Study.

Chen CT, Fernández-Rhodes L et al.

Hum Mol Genet

Menarche and menopause (age at onset)

2011-11-30