Active: Response to hepatitis C treatment Clear all

GWAS 2011-11-16

Serum ferritin levels are associated with a distinct phenotype of chronic hepatitis C poorly responding to pegylated interferon-alpha and ribavirin therapy.

Lange CM, Kutalik Z et al.

Hepatology

Elevated serum ferritin levels may reflect a systemic inflammatory state as well as increased iron s...

Response to hepatitis C treatment

707

Participants

N/A

Studies

Details PubMed

GWAS 2011-06-09

Genome-wide association study identified ITPA/DDRGK1 variants reflecting thrombocytopenia in pegylated interferon and ribavirin therapy for chronic hepatitis C.

Tanaka Y, Kurosaki M et al.

Hum Mol Genet

Hematologic abnormalities during current therapy with pegylated interferon and ribavirin (PEG-IFN/RB...

Response to hepatitis C treatment

Replicated

694

Participants

N/A

Studies

Details PubMed

GWAS 2011-01-12

IL-28B predicts response to chronic hepatitis C therapy--fine-mapping and replication study in Asian populations.

Ochi H, Maekawa T et al.

J Gen Virol

Type I interferon (IFN) is used for the treatment of chronic hepatitis C virus (HCV) infection. Desp...

Response to hepatitis C treatment

2383

Participants

N/A

Studies

Details PubMed

GWAS 2009-09-13

Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C.

Tanaka Y, Nishida N et al.

Nat Genet

The recommended treatment for patients with chronic hepatitis C, pegylated interferon-alpha (PEG-IFN...

Response to hepatitis C treatment

Replicated

314

Participants

N/A

Studies

Details PubMed

GWAS 2009-09-13

IL28B is associated with response to chronic hepatitis C interferon-alpha and ribavirin therapy.

Suppiah V, Moldovan M et al.

Nat Genet

Hepatitis C virus (HCV) infects 3% of the world's population. Treatment of chronic HCV consists of a...

Response to hepatitis C treatment

Replicated

848

Participants

N/A

Studies

Details PubMed

GWAS 2009-08-16

Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance.

Ge D, Fellay J et al.

Nature

Chronic infection with hepatitis C virus (HCV) affects 170 million people worldwide and is the leadi...

Response to hepatitis C treatment

1137

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Serum ferritin levels are associated with a distinct phenotype of chronic hepatitis C poorly responding to pegylated interferon-alpha and ribavirin therapy.

Lange CM, Kutalik Z et al.

Hepatology

Response to hepatitis C treatment

2011-11-16

Genome-wide association study identified ITPA/DDRGK1 variants reflecting thrombocytopenia in pegylated interferon and ribavirin therapy for chronic hepatitis C.

Tanaka Y, Kurosaki M et al.

Hum Mol Genet

Response to hepatitis C treatment

2011-06-09

IL-28B predicts response to chronic hepatitis C therapy--fine-mapping and replication study in Asian populations.

Ochi H, Maekawa T et al.

J Gen Virol

Response to hepatitis C treatment

2011-01-12

Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C.

Tanaka Y, Nishida N et al.

Nat Genet

Response to hepatitis C treatment

2009-09-13

IL28B is associated with response to chronic hepatitis C interferon-alpha and ribavirin therapy.

Suppiah V, Moldovan M et al.

Nat Genet

Response to hepatitis C treatment

2009-09-13

Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance.

Ge D, Fellay J et al.

Nature

Response to hepatitis C treatment

2009-08-16