Active: Severe cutaneous adverse drug reactions Clear all

GWAS 2022-02-16

Potential role of regulatory DNA variants in modifying the risk of severe cutaneous reactions induced by aromatic anti-seizure medications.

Mullan KA, Anderson A et al.

Epilepsia

Objective: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe cutaneous ...

Aromatic antiseizure medication-induced Stevens-Johnson syndrome or toxic epidermal necrolysis

197

Participants

N/A

Studies

Details PubMed

GWAS 2018-09-01

The Fas Signaling Pathway Is a Common Genetic Risk Factor for Severe Cutaneous Drug Adverse Reactions Across Diverse Drugs.

Park HW, Kim SH et al.

Allergy Asthma Immunol Res

Purpose: Human leukocyte antigen (HLA) has been recognized as the most important genetic risk factor...

Severe cutaneous adverse drug reactions

Replicated

530

Participants

N/A

Studies

Details PubMed

GWAS 2011-07-29

Genome-wide association study of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in Europe.

Génin E, Schumacher M et al.

Orphanet J Rare Dis

Stevens-Johnson syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are rare but extremely severe cu...

Drug-induced Stevens-Johnson syndrome or toxic epidermal necrolysis (SJS/TEN)

2305

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Potential role of regulatory DNA variants in modifying the risk of severe cutaneous reactions induced by aromatic anti-seizure medications.

Mullan KA, Anderson A et al.

Epilepsia

Aromatic antiseizure medication-induced Stevens-Johnson syndrome or toxic epidermal necrolysis

2022-02-16

The Fas Signaling Pathway Is a Common Genetic Risk Factor for Severe Cutaneous Drug Adverse Reactions Across Diverse Drugs.

Park HW, Kim SH et al.

Allergy Asthma Immunol Res

Severe cutaneous adverse drug reactions

2018-09-01

Genome-wide association study of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in Europe.

Génin E, Schumacher M et al.

Orphanet J Rare Dis

Drug-induced Stevens-Johnson syndrome or toxic epidermal necrolysis (SJS/TEN)

2011-07-29