Active: Subcutaneous adipose tissue Clear all

GWAS 2025-07-01

Investigating the shared genetic architecture between adiposity measures and obesity-related cancers.

Wang S, Liu H et al.

Brief Bioinform

Fat distribution patterns are increasingly linked to obesity-related cancers; however, their shared ...

Leg fat ratio or ovarian cancer (pleiotropy)

127582

Participants

N/A

Studies

Details PubMed

GWAS 2022-11-19

The link between liver fat and cardiometabolic diseases is highlighted by genome-wide association study of MRI-derived measures of body composition.

van der Meer D, Gurholt TP et al.

Commun Biol

Obesity and associated morbidities, metabolic associated fatty liver disease (MAFLD) included, const...

Abdominal subcutaneous adipose tissue

33532

Participants

N/A

Studies

Details PubMed

GWAS 2022-11-16

Genome-wide association study of a lipedema phenotype among women in the UK Biobank identifies multiple genetic risk factors.

Klimentidis YC, Chen Z et al.

Eur J Hum Genet

Lipedema is a common disorder characterized by excessive deposition of subcutaneous adipose tissue (...

Lipedema

Replicated

195655

Participants

N/A

Studies

Details PubMed

GWAS 2021-05-12

Genetic evidence for different adiposity phenotypes and their opposing influence on ectopic fat and risk of cardiometabolic disease.

Martin S, Cule M et al.

Diabetes

To understand the causal role of adiposity and ectopic fat in type 2 diabetes and cardiometabolic di...

Body fat percentage

442278

Participants

N/A

Studies

Details PubMed

GWAS 2020-05-04

Multifaceted genome-wide study identifies novel regulatory loci in SLC22A11 and ZNF45 for body mass index in Indians.

Giri AK, Prasad G et al.

Mol Genet Genomics

Obesity, a risk factor for multiple diseases (e.g. diabetes, hypertension, cancers) originates throu...

Body mass index

Replicated

7259

Participants

N/A

Studies

Details PubMed

GWAS 2020-01-24

The derived allele of a novel intergenic variant at chromosome 11 associates with lower body mass index and a favorable metabolic phenotype in Greenlanders.

Andersen MK, Jørsboe E et al.

PLoS Genet

The genetic architecture of the small and isolated Greenlandic population is advantageous for identi...

Body mass index

Replicated

7213

Participants

N/A

Studies

Details PubMed

GWAS 2019-07-30

Genome-Wide Association Study of Metabolic Syndrome Reveals Primary Genetic Variants at CETP Locus in Indians.

Prasad G, Bandesh K et al.

Biomolecules

Indians, a rapidly growing population, constitute vast genetic heterogeneity to that of Western popu...

Metabolic syndrome

Replicated

10093

Participants

N/A

Studies

Details PubMed

GWAS 2019-06-12

A Trans-Ethnic Genome-Wide Association Study of Uterine Fibroids.

Edwards TL, Giri A et al.

Front Genet

Uterine fibroids affect up to 77% of women by menopause and account for up to $34 billion in healthc...

Uterine fibroids

Replicated

230274

Participants

N/A

Studies

Details PubMed

GWAS 2019-03-25

Genome-wide association study of blood lipids in Indians confirms universality of established variants.

Bandesh K, Prasad G et al.

J Hum Genet

Lipids foster energy production and their altered levels have been coupled with metabolic ailments. ...

Low density lipoprotein cholesterol levels

Replicated

201746

Participants

N/A

Studies

Details PubMed

GWAS 2018-09-27

Using Adipose Measures from Health Care Provider-Based Imaging Data for Discovery.

Cha EDK, Veturi Y et al.

J Obes

The location and type of adipose tissue is an important factor in metabolic syndrome. A database of ...

Subcutaneous adipose tissue

2545

Participants

N/A

Studies

Details PubMed

GWAS 2017-02-21

Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.

Spracklen CN, Chen P et al.

Hum Mol Genet

Large-scale meta-analyses of genome-wide association studies (GWAS) have identified >175 loci ass...

Total cholesterol levels

Replicated

80304

Participants

N/A

Studies

Details PubMed

GWAS 2016-12-05

Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation.

Chu AY, Deng X et al.

Nat Genet

Variation in body fat distribution contributes to the metabolic sequelae of obesity. The genetic det...

Subcutaneous adipose tissue

18247

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Investigating the shared genetic architecture between adiposity measures and obesity-related cancers.

Wang S, Liu H et al.

Brief Bioinform

Leg fat ratio or ovarian cancer (pleiotropy)

2025-07-01

The link between liver fat and cardiometabolic diseases is highlighted by genome-wide association study of MRI-derived measures of body composition.

van der Meer D, Gurholt TP et al.

Commun Biol

Abdominal subcutaneous adipose tissue

2022-11-19

Genome-wide association study of a lipedema phenotype among women in the UK Biobank identifies multiple genetic risk factors.

Klimentidis YC, Chen Z et al.

Eur J Hum Genet

Lipedema

2022-11-16

Genetic evidence for different adiposity phenotypes and their opposing influence on ectopic fat and risk of cardiometabolic disease.

Martin S, Cule M et al.

Diabetes

Body fat percentage

2021-05-12

Multifaceted genome-wide study identifies novel regulatory loci in SLC22A11 and ZNF45 for body mass index in Indians.

Giri AK, Prasad G et al.

Mol Genet Genomics

Body mass index

2020-05-04

The derived allele of a novel intergenic variant at chromosome 11 associates with lower body mass index and a favorable metabolic phenotype in Greenlanders.

Andersen MK, Jørsboe E et al.

PLoS Genet

Body mass index

2020-01-24

Genome-Wide Association Study of Metabolic Syndrome Reveals Primary Genetic Variants at CETP Locus in Indians.

Prasad G, Bandesh K et al.

Biomolecules

Metabolic syndrome

2019-07-30

A Trans-Ethnic Genome-Wide Association Study of Uterine Fibroids.

Edwards TL, Giri A et al.

Front Genet

Uterine fibroids

2019-06-12

Genome-wide association study of blood lipids in Indians confirms universality of established variants.

Bandesh K, Prasad G et al.

J Hum Genet

Low density lipoprotein cholesterol levels

2019-03-25

Using Adipose Measures from Health Care Provider-Based Imaging Data for Discovery.

Cha EDK, Veturi Y et al.

J Obes

Subcutaneous adipose tissue

2018-09-27

Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.

Spracklen CN, Chen P et al.

Hum Mol Genet

Total cholesterol levels

2017-02-21

Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation.

Chu AY, Deng X et al.

Nat Genet

Subcutaneous adipose tissue

2016-12-05