Active: Vitiligo Clear all

GWAS 2024-01-27

Genome-wide meta-analysis identifies 11 susceptibility variants of vitiligo in the Chinese Han population.

Wang D, Chen W et al.

J Invest Dermatol

Vitiligo is an autoimmune disease involving loss of melanocytes. Although several genetic studies ha...

Vitiligo

13327

Participants

N/A

Studies

Details PubMed

GWAS 2023-01-05

Skin Phototype and Disease: A Comprehensive Genetic Approach to Pigmentary Traits Pleiotropy Using PRS in the GCAT Cohort.

Farré X, Blay N et al.

Genes (Basel)

Human pigmentation has largely been associated with different disease prevalence among populations, ...

Red vs non-red hair color

4979

Participants

N/A

Studies

Details PubMed

GWAS 2020-06-18

Genome-wide association study identifies CDH13 as a susceptibility gene for rhododendrol-induced leukoderma.

Okamura K, Abe Y et al.

Pigment Cell Melanoma Res

Racemic RS-4-(4-hydroxyphenyl)-2-butanol (rhododendrol; trade name: Rhododenol [RD]), which is used ...

Leukoderma in response to rhododendrol

259

Participants

N/A

Studies

Details PubMed

GWAS 2019-01-23

Early-onset autoimmune vitiligo associated with an enhancer variant haplotype that upregulates class II HLA expression.

Jin Y, Roberts GHL et al.

Nat Commun

Vitiligo is an autoimmune disease in which melanocyte destruction causes skin depigmentation, with 4...

Vitiligo (late onset)

Replicated

22327

Participants

N/A

Studies

Details PubMed

GWAS 2016-11-01

Genome-wide association studies of autoimmune vitiligo identify 23 new risk loci and highlight key pathways and regulatory variants.

Jin Y, Andersen G et al.

Nat Genet

Vitiligo is an autoimmune disease in which depigmented skin results from the destruction of melanocy...

Vitiligo

Replicated

44266

Participants

N/A

Studies

Details PubMed

GWAS 2013-05-02

Three new single nucleotide polymorphisms identified by a genome-wide association study in Korean patients with vitiligo.

Cheong KA, Kim NH et al.

J Korean Med Sci

Genetic susceptibility is involved in the pathogenesis of vitiligo. Association studies with a whole...

Vitiligo (non-segmental)

Replicated

588

Participants

N/A

Studies

Details PubMed

GWAS 2012-09-06

Association analyses identify three susceptibility Loci for vitiligo in the Chinese Han population.

Tang XF, Zhang Z et al.

J Invest Dermatol

To identify susceptibility loci for vitiligo, we extended our previous vitiligo genome-wide associat...

Vitiligo

Replicated

18882

Participants

N/A

Studies

Details PubMed

GWAS 2012-05-06

Genome-wide association analyses identify 13 new susceptibility loci for generalized vitiligo.

Jin Y, Birlea SA et al.

Nat Genet

We previously reported a genome-wide association study (GWAS) identifying 14 susceptibility loci for...

Vitiligo

Replicated

5889

Participants

N/A

Studies

Details PubMed

GWAS 2011-02-17

Genome-wide analysis identifies a quantitative trait locus in the MHC class II region associated with generalized vitiligo age of onset.

Jin Y, Birlea SA et al.

J Invest Dermatol

Generalized vitiligo is a common autoimmune disease in which acquired patchy depigmentation of skin,...

Vitiligo

Replicated

2016

Participants

N/A

Studies

Details PubMed

GWAS 2010-06-06

Genome-wide association study for vitiligo identifies susceptibility loci at 6q27 and the MHC.

Quan C, Ren YQ et al.

Nat Genet

We conducted a genome-wide association study of generalized vitiligo in the Chinese Han population b...

Vitiligo

Replicated

19909

Participants

N/A

Studies

Details PubMed

GWAS 2010-04-21

Variant of TYR and autoimmunity susceptibility loci in generalized vitiligo.

Jin Y, Birlea SA et al.

N Engl J Med

Generalized vitiligo is an autoimmune disease characterized by melanocyte loss, which results in pat...

Vitiligo

Replicated

7656

Participants

N/A

Studies

Details PubMed

GWAS 2009-11-05

Genome-wide association study of generalized vitiligo in an isolated European founder population identifies SMOC2, in close proximity to IDDM8.

Birlea SA, Gowan K et al.

J Invest Dermatol

Generalized vitiligo is a common disorder in which patchy loss of skin and hair pigmentation princip...

Vitiligo

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Genome-wide meta-analysis identifies 11 susceptibility variants of vitiligo in the Chinese Han population.

Wang D, Chen W et al.

J Invest Dermatol

Vitiligo

2024-01-27

Skin Phototype and Disease: A Comprehensive Genetic Approach to Pigmentary Traits Pleiotropy Using PRS in the GCAT Cohort.

Farré X, Blay N et al.

Genes (Basel)

Red vs non-red hair color

2023-01-05

Genome-wide association study identifies CDH13 as a susceptibility gene for rhododendrol-induced leukoderma.

Okamura K, Abe Y et al.

Pigment Cell Melanoma Res

Leukoderma in response to rhododendrol

2020-06-18

Early-onset autoimmune vitiligo associated with an enhancer variant haplotype that upregulates class II HLA expression.

Jin Y, Roberts GHL et al.

Nat Commun

Vitiligo (late onset)

2019-01-23

Genome-wide association studies of autoimmune vitiligo identify 23 new risk loci and highlight key pathways and regulatory variants.

Jin Y, Andersen G et al.

Nat Genet

Vitiligo

2016-11-01

Three new single nucleotide polymorphisms identified by a genome-wide association study in Korean patients with vitiligo.

Cheong KA, Kim NH et al.

J Korean Med Sci

Vitiligo (non-segmental)

2013-05-02

Association analyses identify three susceptibility Loci for vitiligo in the Chinese Han population.

Tang XF, Zhang Z et al.

J Invest Dermatol

Vitiligo

2012-09-06

Genome-wide association analyses identify 13 new susceptibility loci for generalized vitiligo.

Jin Y, Birlea SA et al.

Nat Genet

Vitiligo

2012-05-06

Genome-wide analysis identifies a quantitative trait locus in the MHC class II region associated with generalized vitiligo age of onset.

Jin Y, Birlea SA et al.

J Invest Dermatol

Vitiligo

2011-02-17

Genome-wide association study for vitiligo identifies susceptibility loci at 6q27 and the MHC.

Quan C, Ren YQ et al.

Nat Genet

Vitiligo

2010-06-06

Variant of TYR and autoimmunity susceptibility loci in generalized vitiligo.

Jin Y, Birlea SA et al.

N Engl J Med

Vitiligo

2010-04-21

Genome-wide association study of generalized vitiligo in an isolated European founder population identifies SMOC2, in close proximity to IDDM8.

Birlea SA, Gowan K et al.

J Invest Dermatol

Vitiligo

2009-11-05