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GWAS 2021-12-07

Associations between electronic devices use and common mental traits: A gene-environment interaction model using the UK Biobank data.

Ye J, Cheng S et al.

Addict Biol

Electronic devices use has been reported to be associated with depression. However, limited effort h...

Depression severity x hours spent using computers interaction

488377

Participants

N/A

Studies

Details PubMed

GWAS 2020-04-13

Gene-based association analysis reveals involvement of LAMA5 and cell adhesion pathways in nicotine dependence in African- and European-American samples.

Fan R, Cui W et al.

Addict Biol

Nicotine dependence (ND) is a chronic brain disorder that causes heavy social and economic burdens. ...

Nicotine dependence

Replicated

4943

Participants

N/A

Studies

Details PubMed

GWAS 2019-07-30

Genome-wide scan identifies opioid overdose risk locus close to MCOLN1.

Cheng Z, Yang BZ et al.

Addict Biol

The United States is experiencing the worst opioid overdose (OpOD) crisis in its history. We carried...

Opioid overdose severity score

3477

Participants

N/A

Studies

Details PubMed

GWAS 2019-07-03

Genome-wide association studies of the self-rating of effects of ethanol (SRE).

Lai D, Wetherill L et al.

Addict Biol

The level of response (LR) to alcohol as measured with the Self-Report of the Effects of Alcohol Ret...

Number of alcoholic drinks required to feel an effect (first five times drinking)

Replicated

6725

Participants

N/A

Studies

Details PubMed

GWAS 2018-03-13

Genome-wide association study in Finnish twins highlights the connection between nicotine addiction and neurotrophin signaling pathway.

Hällfors J, Palviainen T et al.

Addict Biol

The heritability of nicotine dependence based on family studies is substantial. Nevertheless, knowle...

Smoking behaviour (cigarettes smoked per day)

Replicated

9059

Participants

N/A

Studies

Details PubMed

GWAS 2017-10-30

Problematic alcohol use associates with sodium channel and clathrin linker 1 (SCLT1) in trauma-exposed populations.

Almli LM, Lori A et al.

Addict Biol

Excessive alcohol use is extremely prevalent in the United States, particularly among trauma-exposed...

Problematic alcohol use in trauma-exposed individuals

Replicated

2430

Participants

N/A

Studies

Details PubMed

GWAS 2017-10-23

Genome-wide association study of alcohol use disorder identification test (AUDIT) scores in 20 328 research participants of European ancestry.

Sanchez-Roige S, Fontanillas P et al.

Addict Biol

Genetic factors contribute to the risk for developing alcohol use disorder (AUD). In collaboration w...

Alcohol consumption over the past year

20328

Participants

N/A

Studies

Details PubMed

GWAS 2016-07-23

KAT2B polymorphism identified for drug abuse in African Americans with regulatory links to drug abuse pathways in human prefrontal cortex.

Johnson EO, Hancock DB et al.

Addict Biol

Drug abuse is a common and heritable set of disorders, but the underlying genetic factors are largel...

Drug abuse

Replicated

12473

Participants

N/A

Studies

Details PubMed

GWAS 2016-05-05

An association study revealed substantial effects of dominance, epistasis and substance dependence co-morbidity on alcohol dependence symptom count.

Chen G, Zhang F et al.

Addict Biol

Alcohol dependence is a complex disease involving polygenes, environment and their interactions. Ina...

Alcohol dependence symptom count

3838

Participants

N/A

Studies

Details PubMed

GWAS 2014-05-16

Association of substance dependence phenotypes in the COGA sample.

Wetherill L, Agrawal A et al.

Addict Biol

Alcohol and drug use disorders are individually heritable (50%). Twin studies indicate that alcohol ...

Substance dependence phenotypes

Replicated

4969

Participants

N/A

Studies

Details PubMed

GWAS 2012-07-24

The genetic aetiology of cannabis use initiation: a meta-analysis of genome-wide association studies and a SNP-based heritability estimation.

Verweij KJ, Vinkhuyzen AA et al.

Addict Biol

While initiation of cannabis use is around 40% heritable, not much is known about the underlying gen...

Cannabis use (initiation)

10091

Participants

N/A

Studies

Details PubMed

GWAS 2012-07-11

Genome-wide association study of a quantitative disordered gambling trait.

Lind PA, Zhu G et al.

Addict Biol

Disordered gambling is a moderately heritable trait, but the underlying genetic basis is largely unk...

Gambling

1312

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Associations between electronic devices use and common mental traits: A gene-environment interaction model using the UK Biobank data.

Ye J, Cheng S et al.

Addict Biol

Depression severity x hours spent using computers interaction

2021-12-07

Gene-based association analysis reveals involvement of LAMA5 and cell adhesion pathways in nicotine dependence in African- and European-American samples.

Fan R, Cui W et al.

Addict Biol

Nicotine dependence

2020-04-13

Genome-wide scan identifies opioid overdose risk locus close to MCOLN1.

Cheng Z, Yang BZ et al.

Addict Biol

Opioid overdose severity score

2019-07-30

Genome-wide association studies of the self-rating of effects of ethanol (SRE).

Lai D, Wetherill L et al.

Addict Biol

Number of alcoholic drinks required to feel an effect (first five times drinking)

2019-07-03

Genome-wide association study in Finnish twins highlights the connection between nicotine addiction and neurotrophin signaling pathway.

Hällfors J, Palviainen T et al.

Addict Biol

Smoking behaviour (cigarettes smoked per day)

2018-03-13

Problematic alcohol use associates with sodium channel and clathrin linker 1 (SCLT1) in trauma-exposed populations.

Almli LM, Lori A et al.

Addict Biol

Problematic alcohol use in trauma-exposed individuals

2017-10-30

Genome-wide association study of alcohol use disorder identification test (AUDIT) scores in 20 328 research participants of European ancestry.

Sanchez-Roige S, Fontanillas P et al.

Addict Biol

Alcohol consumption over the past year

2017-10-23

KAT2B polymorphism identified for drug abuse in African Americans with regulatory links to drug abuse pathways in human prefrontal cortex.

Johnson EO, Hancock DB et al.

Addict Biol

Drug abuse

2016-07-23

An association study revealed substantial effects of dominance, epistasis and substance dependence co-morbidity on alcohol dependence symptom count.

Chen G, Zhang F et al.

Addict Biol

Alcohol dependence symptom count

2016-05-05

Association of substance dependence phenotypes in the COGA sample.

Wetherill L, Agrawal A et al.

Addict Biol

Substance dependence phenotypes

2014-05-16

The genetic aetiology of cannabis use initiation: a meta-analysis of genome-wide association studies and a SNP-based heritability estimation.

Verweij KJ, Vinkhuyzen AA et al.

Addict Biol

Cannabis use (initiation)

2012-07-24

Genome-wide association study of a quantitative disordered gambling trait.

Lind PA, Zhu G et al.

Addict Biol

Gambling

2012-07-11