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GWAS 2023-01-09

Genome-wide analyses of platinum-induced ototoxicity in childhood cancer patients: Results of GO-CAT and United Kingdom MAGIC consortia.

Hurkmans EGE, Klumpers MJ et al.

Front Pharmacol

Hearing loss (ototoxicity) is a major adverse effect of cisplatin and carboplatin chemotherapy. The ...

Platinum-induced ototoxicity in childhood cancer

Replicated

899

Participants

N/A

Studies

Details PubMed

GWAS 2022-09-23

A genome-wide association study of plasma concentrations of warfarin enantiomers and metabolites in sub-Saharan black-African patients.

Asiimwe IG, Blockman M et al.

Front Pharmacol

Diversity in pharmacogenomic studies is poor, especially in relation to the inclusion of black Afric...

S-warfarin levels

531

Participants

N/A

Studies

Details PubMed

GWAS 2022-01-05

The Pharmacogenetics of Statin Therapy on Clinical Events: No Evidence that Genetic Variation Affects Statin Response on Myocardial Infarction.

Trompet S, Postmus I et al.

Front Pharmacol

The pharmacogenetic effect on cardiovascular disease reduction in response to statin treatment has o...

Myocardial infraction risk reduction in statin users

Replicated

12294

Participants

N/A

Studies

Details PubMed

GWAS 2021-06-09

Role of Common Genetic Variants for Drug-Resistance to Specific Anti-Seizure Medications.

Wolking S, Campbell C et al.

Front Pharmacol

Objective: Resistance to anti-seizure medications (ASMs) presents a significant hurdle in the treatm...

Response to levetiracetam in focal epilepsy

936

Participants

N/A

Studies

Details PubMed

GWAS 2021-04-22

Robust Performance of Potentially Functional SNPs in Machine Learning Models for the Prediction of Atorvastatin-Induced Myalgia.

Ooi BNS, Raechell None et al.

Front Pharmacol

Statins can cause muscle symptoms resulting in poor adherence to therapy and increased cardiovascula...

Atorvastatin-induced myalgia

183

Participants

N/A

Studies

Details PubMed

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Genome-wide analyses of platinum-induced ototoxicity in childhood cancer patients: Results of GO-CAT and United Kingdom MAGIC consortia.

Hurkmans EGE, Klumpers MJ et al.

Front Pharmacol

Platinum-induced ototoxicity in childhood cancer

2023-01-09

A genome-wide association study of plasma concentrations of warfarin enantiomers and metabolites in sub-Saharan black-African patients.

Asiimwe IG, Blockman M et al.

Front Pharmacol

S-warfarin levels

2022-09-23

The Pharmacogenetics of Statin Therapy on Clinical Events: No Evidence that Genetic Variation Affects Statin Response on Myocardial Infarction.

Trompet S, Postmus I et al.

Front Pharmacol

Myocardial infraction risk reduction in statin users

2022-01-05

Role of Common Genetic Variants for Drug-Resistance to Specific Anti-Seizure Medications.

Wolking S, Campbell C et al.

Front Pharmacol

Response to levetiracetam in focal epilepsy

2021-06-09

Robust Performance of Potentially Functional SNPs in Machine Learning Models for the Prediction of Atorvastatin-Induced Myalgia.

Ooi BNS, Raechell None et al.

Front Pharmacol

Atorvastatin-induced myalgia

2021-04-22