Active: Genes Immun Clear all

GWAS 2021-06-14

Variants in BANK1 are associated with lupus nephritis of European ancestry.

Bolin K, Imgenberg-Kreuz J et al.

Genes Immun

The genetic background of lupus nephritis (LN) has not been completely elucidated. We performed a ca...

Lupus nephritis in systemic lupus erythematosus

Replicated

2886

Participants

N/A

Studies

Details PubMed

GWAS 2020-01-14

Analysis of the genetic variants associated with circulating levels of sgp130. Results from the IMPROVE study.

Bonomi A, Veglia F et al.

Genes Immun

The genes regulating circulating levels of soluble gp130 (sgp130), the antagonist of the inflammator...

Soluble gp130 levels

3439

Participants

N/A

Studies

Details PubMed

GWAS 2018-06-08

Genetic variants at the 16p13 locus confer risk for eosinophilic esophagitis.

Kottyan LC, Maddox A et al.

Genes Immun

Eosinophilic esophagitis (EoE) is a chronic inflammatory disease of the esophagus triggered by immun...

Eosinophilic esophagitis

4944

Participants

N/A

Studies

Details PubMed

GWAS 2018-02-28

Genome-wide association study (GWAS) of human host factors influencing viral severity of herpes simplex virus type 2 (HSV-2).

Kleinstein SE, Shea PR et al.

Genes Immun

Herpes simplex virus type 2 (HSV-2) is an incurable viral infection with severity ranging from asymp...

Virologic severity in Herpes simplex virus type 2 infection

223

Participants

N/A

Studies

Details PubMed

GWAS 2016-01-07

Genome-wide association study of antibody responses to Plasmodium falciparum candidate vaccine antigens.

Milet J, Sabbagh A et al.

Genes Immun

We conducted a genome-wide association study (GWAS) of antibody responses directed to three Plasmodi...

IgG1 response to Plasmodium falciparum antigen (GLURP)

528

Participants

N/A

Studies

Details PubMed

GWAS 2015-08-20

Genome-wide association study identifies HLA 8.1 ancestral haplotype alleles as major genetic risk factors for myositis phenotypes.

Miller FW, Chen W et al.

Genes Immun

Autoimmune muscle diseases (myositis) comprise a group of complex phenotypes influenced by genetic a...

Myositis

6434

Participants

N/A

Studies

Details PubMed

GWAS 2014-10-23

Genetic analysis of the pathogenic molecular sub-phenotype interferon-alpha identifies multiple novel loci involved in systemic lupus erythematosus.

Kariuki SN, Ghodke-Puranik Y et al.

Genes Immun

Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder characterized by inflammation of...

Interferon alpha levels in systemic lupus erythematosus

Replicated

1575

Participants

N/A

Studies

Details PubMed

GWAS 2014-10-09

Genetic variation in the HLA region is associated with susceptibility to herpes zoster.

Crosslin DR, Carrell DS et al.

Genes Immun

Herpes zoster, commonly referred to as shingles, is caused by the varicella zoster virus (VZV). VZV ...

Shingles

22529

Participants

N/A

Studies

Details PubMed

GWAS 2014-09-11

Genome-wide association study of vitamin D levels in children: replication in the Western Australian Pregnancy Cohort (Raine) study.

Anderson D, Holt BJ et al.

Genes Immun

This genome-wide association study (GWAS) utilises data from the Western Australian Pregnancy Cohort...

Vitamin D levels

1813

Participants

N/A

Studies

Details PubMed

GWAS 2014-07-17

Genome-wide association study of hepatitis C virus- and cryoglobulin-related vasculitis.

Zignego AL, Wojcik GL et al.

Genes Immun

The host genetic basis of mixed cryoglobulin vasculitis is not well understood and has not been stud...

Mixed cryoglobulinemia vasculitis in chronic hepatitis C infection

Replicated

1254

Participants

N/A

Studies

Details PubMed

GWAS 2014-05-29

GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

Armstrong DL, Zidovetzki R et al.

Genes Immun

In a genome-wide association study (GWAS) of individuals of European ancestry afflicted with systemi...

Systemic lupus erythematosus

3163

Participants

N/A

Studies

Details PubMed

GWAS 2012-07-07

Genome-wide association study identifies common variants at TNFRSF13B associated with IgG level in a healthy Chinese male population.

Liao M, Ye F et al.

Genes Immun

IgG has a crucial role in humoral immune response. Serum IgG level is mainly determined under geneti...

IgG levels

Replicated

3495

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Variants in BANK1 are associated with lupus nephritis of European ancestry.

Bolin K, Imgenberg-Kreuz J et al.

Genes Immun

Lupus nephritis in systemic lupus erythematosus

2021-06-14

Analysis of the genetic variants associated with circulating levels of sgp130. Results from the IMPROVE study.

Bonomi A, Veglia F et al.

Genes Immun

Soluble gp130 levels

2020-01-14

Genetic variants at the 16p13 locus confer risk for eosinophilic esophagitis.

Kottyan LC, Maddox A et al.

Genes Immun

Eosinophilic esophagitis

2018-06-08

Genome-wide association study (GWAS) of human host factors influencing viral severity of herpes simplex virus type 2 (HSV-2).

Kleinstein SE, Shea PR et al.

Genes Immun

Virologic severity in Herpes simplex virus type 2 infection

2018-02-28

Genome-wide association study of antibody responses to Plasmodium falciparum candidate vaccine antigens.

Milet J, Sabbagh A et al.

Genes Immun

IgG1 response to Plasmodium falciparum antigen (GLURP)

2016-01-07

Genome-wide association study identifies HLA 8.1 ancestral haplotype alleles as major genetic risk factors for myositis phenotypes.

Miller FW, Chen W et al.

Genes Immun

Myositis

2015-08-20

Genetic analysis of the pathogenic molecular sub-phenotype interferon-alpha identifies multiple novel loci involved in systemic lupus erythematosus.

Kariuki SN, Ghodke-Puranik Y et al.

Genes Immun

Interferon alpha levels in systemic lupus erythematosus

2014-10-23

Genetic variation in the HLA region is associated with susceptibility to herpes zoster.

Crosslin DR, Carrell DS et al.

Genes Immun

Shingles

2014-10-09

Genome-wide association study of vitamin D levels in children: replication in the Western Australian Pregnancy Cohort (Raine) study.

Anderson D, Holt BJ et al.

Genes Immun

Vitamin D levels

2014-09-11

Genome-wide association study of hepatitis C virus- and cryoglobulin-related vasculitis.

Zignego AL, Wojcik GL et al.

Genes Immun

Mixed cryoglobulinemia vasculitis in chronic hepatitis C infection

2014-07-17

GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

Armstrong DL, Zidovetzki R et al.

Genes Immun

Systemic lupus erythematosus

2014-05-29

Genome-wide association study identifies common variants at TNFRSF13B associated with IgG level in a healthy Chinese male population.

Liao M, Ye F et al.

Genes Immun

IgG levels

2012-07-07