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GWAS 2024-06-05

Whole exome sequencing analyses reveal novel genes in telomere length and their biomedical implications.

Liu WS, Wu BS et al.

Geroscience

Telomere length is a putative biomarker of aging and is associated with multiple age-related disease...

Leukocyte telomere length

327790

Participants

N/A

Studies

Details PubMed

GWAS 2023-03-16

A genome-wide association study of frailty identifies significant genetic correlation with neuropsychiatric, cardiovascular, and inflammation pathways.

Ye Y, Noche RB et al.

Geroscience

Frailty is an aging-related clinical phenotype defined as a state in which there is an increase in a...

Fried Frailty Score

Replicated

396285

Participants

N/A

Studies

Details PubMed

GWAS 2021-11-06

Pleiotropic predisposition to Alzheimer's disease and educational attainment: insights from the summary statistics analysis.

Kulminski AM, Loiko E et al.

Geroscience

Epidemiological studies report beneficial associations of higher educational attainment (EDU) with A...

Alzheimer's disease or educational attainment (pleiotropy)

N/A

Participants

N/A

Studies

Details PubMed

GWAS 2021-05-04

Effect of longevity genetic variants on the molecular aging rate.

Gurinovich A, Song Z et al.

Geroscience

We conducted a genome-wide association study of 1320 centenarians from the New England Centenarian S...

Longevity (100 years and older)

Replicated

5169

Participants

N/A

Studies

Details PubMed

GWAS 2019-11-09

Polygenic risk score for disability and insights into disability-related molecular mechanisms.

Kulminski AM, Kang C et al.

Geroscience

Late life disability is a highly devastating condition affecting 20% or more of persons aged 65 year...

Disability (impaired activities of daily living)

Replicated

24068

Participants

N/A

Studies

Details PubMed

GWAS 2019-05-05

Genetic heterogeneity of Alzheimer's disease in subjects with and without hypertension.

Nazarian A, Arbeev KG et al.

Geroscience

Alzheimer's disease (AD) is a progressive neurodegenerative disorder caused by the interplay of mult...

Alzheimer's disease in hypertension-negative individuals

4806

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Whole exome sequencing analyses reveal novel genes in telomere length and their biomedical implications.

Liu WS, Wu BS et al.

Geroscience

Leukocyte telomere length

2024-06-05

A genome-wide association study of frailty identifies significant genetic correlation with neuropsychiatric, cardiovascular, and inflammation pathways.

Ye Y, Noche RB et al.

Geroscience

Fried Frailty Score

2023-03-16

Pleiotropic predisposition to Alzheimer's disease and educational attainment: insights from the summary statistics analysis.

Kulminski AM, Loiko E et al.

Geroscience

Alzheimer's disease or educational attainment (pleiotropy)

2021-11-06

Effect of longevity genetic variants on the molecular aging rate.

Gurinovich A, Song Z et al.

Geroscience

Longevity (100 years and older)

2021-05-04

Polygenic risk score for disability and insights into disability-related molecular mechanisms.

Kulminski AM, Kang C et al.

Geroscience

Disability (impaired activities of daily living)

2019-11-09

Genetic heterogeneity of Alzheimer's disease in subjects with and without hypertension.

Nazarian A, Arbeev KG et al.

Geroscience

Alzheimer's disease in hypertension-negative individuals

2019-05-05