Active: Hum Reprod Clear all

GWAS 2025-04-22

The phenotypic and genetic association between endometriosis and immunological diseases.

Shigesi N, Harris HR et al.

Hum Reprod

Study question: Is there an increased risk of immunological diseases among endometriosis patients, a...

Ankylosing spondylitis

321025

Participants

N/A

Studies

Details PubMed

GWAS 2025-02-22

A large-scale genome-wide association study on female genital tract polyps highlights role of DNA repair, cell proliferation, and cell growth.

Pathare ADS, Džigurski J et al.

Hum Reprod

Study question: Can a large-scale genome-wide association study (GWAS) meta-analysis identify genomi...

Female genital tract polyps

457977

Participants

N/A

Studies

Details PubMed

GWAS 2024-05-30

Circulating anti-Müllerian hormone levels in pre-menopausal women: novel genetic insights from a genome-wide association meta-analysis.

Pujol-Gualdo N, Karjalainen MK et al.

Hum Reprod

Study question: Can a genome-wide association study (GWAS) meta-analysis, including a large sample o...

Anti-Mullerian hormone levels in pre-menopausal women

9668

Participants

N/A

Studies

Details PubMed

GWAS 2024-03-25

Menarche-a journey into womanhood: age at menarche and health-related outcomes in East Asians.

Chiou JS, Lin YJ et al.

Hum Reprod

Study question: Are there associations of age at menarche (AAM) with health-related outcomes in East...

Age at menarche

57890

Participants

N/A

Studies

Details PubMed

GWAS 2023-12-05

Genome-wide association study meta-analysis of dizygotic twinning illuminates genetic regulation of female fecundity.

Mbarek H, Gordon SD et al.

Hum Reprod

Study question: Which genetic factors regulate female propensity for giving birth to spontaneous diz...

Spontaneous dizygotic twinning

716517

Participants

N/A

Studies

Details PubMed

GWAS 2023-10-24

Genome-wide association study meta-analysis supports association between MUC1 and ectopic pregnancy.

Pujol Gualdo N, Mägi R et al.

Hum Reprod

Study question: Can we identify genetic variants associated with ectopic pregnancy by undertaking th...

Ectopic pregnancy

255880

Participants

N/A

Studies

Details PubMed

GWAS 2022-03-11

Genome-wide association study meta-analysis identifies three novel loci for circulating anti-Müllerian hormone levels in women.

Verdiesen RMG, van der Schouw YT et al.

Hum Reprod

Study question: Can additional genetic variants for circulating anti-Müllerian hormone (AMH) levels ...

Anti-Mullerian hormone levels

7049

Participants

N/A

Studies

Details PubMed

GWAS 2022-01-01

Genetic overlap analysis of endometriosis and asthma identifies shared loci implicating sex hormones and thyroid signalling pathways.

Adewuyi EO, Mehta D et al.

Hum Reprod

Study question: Is there a shared genetic or causal association of endometriosis with asthma or what...

Endometriosis or asthma (pleiotropy)

610749

Participants

N/A

Studies

Details PubMed

GWAS 2021-11-13

Leveraging Northern European population history: novel low-frequency variants for polycystic ovary syndrome.

Tyrmi JS, Arffman RK et al.

Hum Reprod

Study question: Can we identify novel variants associated with polycystic ovary syndrome (PCOS) by l...

Polycystic ovary syndrome (adjusted for age)

Replicated

374753

Participants

N/A

Studies

Details PubMed

GWAS 2021-05-22

Large trans-ethnic meta-analysis identifies AKR1C4 as a novel gene associated with age at menarche.

Sarnowski C, Cousminer DL et al.

Hum Reprod

Study question: Does the expansion of genome-wide association studies (GWAS) to a broader range of a...

Menarche (age at onset)

Replicated

24176

Participants

N/A

Studies

Details PubMed

GWAS 2017-04-01

Genome-wide genetic analyses highlight mitogen-activated protein kinase (MAPK) signaling in the pathogenesis of endometriosis.

Uimari O, Rahmioglu N et al.

Hum Reprod

Study question: Do genome-wide association study (GWAS) data for endometriosis provide insight into ...

Endometriosis

10254

Participants

N/A

Studies

Details PubMed

GWAS 2016-01-04

Genetic evidence that lower circulating FSH levels lengthen menstrual cycle, increase age at menopause and impact female reproductive health.

Ruth KS, Beaumont RN et al.

Hum Reprod

Study question: How does a genetic variant in the FSHB promoter, known to alter FSH levels, impact f...

Length of menstrual cycle

9534

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

The phenotypic and genetic association between endometriosis and immunological diseases.

Shigesi N, Harris HR et al.

Hum Reprod

Ankylosing spondylitis

2025-04-22

A large-scale genome-wide association study on female genital tract polyps highlights role of DNA repair, cell proliferation, and cell growth.

Pathare ADS, Džigurski J et al.

Hum Reprod

Female genital tract polyps

2025-02-22

Circulating anti-Müllerian hormone levels in pre-menopausal women: novel genetic insights from a genome-wide association meta-analysis.

Pujol-Gualdo N, Karjalainen MK et al.

Hum Reprod

Anti-Mullerian hormone levels in pre-menopausal women

2024-05-30

Menarche-a journey into womanhood: age at menarche and health-related outcomes in East Asians.

Chiou JS, Lin YJ et al.

Hum Reprod

Age at menarche

2024-03-25

Genome-wide association study meta-analysis of dizygotic twinning illuminates genetic regulation of female fecundity.

Mbarek H, Gordon SD et al.

Hum Reprod

Spontaneous dizygotic twinning

2023-12-05

Genome-wide association study meta-analysis supports association between MUC1 and ectopic pregnancy.

Pujol Gualdo N, Mägi R et al.

Hum Reprod

Ectopic pregnancy

2023-10-24

Genome-wide association study meta-analysis identifies three novel loci for circulating anti-Müllerian hormone levels in women.

Verdiesen RMG, van der Schouw YT et al.

Hum Reprod

Anti-Mullerian hormone levels

2022-03-11

Genetic overlap analysis of endometriosis and asthma identifies shared loci implicating sex hormones and thyroid signalling pathways.

Adewuyi EO, Mehta D et al.

Hum Reprod

Endometriosis or asthma (pleiotropy)

2022-01-01

Leveraging Northern European population history: novel low-frequency variants for polycystic ovary syndrome.

Tyrmi JS, Arffman RK et al.

Hum Reprod

Polycystic ovary syndrome (adjusted for age)

2021-11-13

Large trans-ethnic meta-analysis identifies AKR1C4 as a novel gene associated with age at menarche.

Sarnowski C, Cousminer DL et al.

Hum Reprod

Menarche (age at onset)

2021-05-22

Genome-wide genetic analyses highlight mitogen-activated protein kinase (MAPK) signaling in the pathogenesis of endometriosis.

Uimari O, Rahmioglu N et al.

Hum Reprod

Endometriosis

2017-04-01

Genetic evidence that lower circulating FSH levels lengthen menstrual cycle, increase age at menopause and impact female reproductive health.

Ruth KS, Beaumont RN et al.

Hum Reprod

Length of menstrual cycle

2016-01-04