Active: J Am Heart Assoc Clear all

GWAS 2025-03-21

Genomic Exploration of Essential Hypertension in African-Brazilian Quilombo Populations: A Comprehensive Approach With Pedigree Analysis and Family-Based Association Studies.

Borges VM, Horimoto ARVR et al.

J Am Heart Assoc

Essential hypertension (EH) is a global health issue. Despite extensive research, much of EH heritab...

Essential hypertension

431

Participants

N/A

Studies

Details PubMed

GWAS 2024-10-18

Genome-Wide Search for Nonadditive Allele Effects Identifies PSKH2 as Involved in the Variability of Factor V Activity.

Gendre B, Martinez-Perez A et al.

J Am Heart Assoc

Factor V (FV) is a key molecular player in the coagulation cascade. FV plasma levels have been assoc...

Plasma factor V levels (parent of origin effect)

4505

Participants

N/A

Studies

Details PubMed

GWAS 2023-12-01

Chromosome 10q24.32 Variants Associate With Brain Arterial Diameters in Diverse Populations: A Genome-Wide Association Study.

Liu M, Khasiyev F et al.

J Am Heart Assoc

Brain arterial diameters (BADs) are novel imaging biomarkers of cerebrovascular disease, cognitive d...

Global brain arterial diameters

4150

Participants

N/A

Studies

Details PubMed

GWAS 2023-11-10

Genome-Wide Assessment of Shared Genetic Architecture Between Rheumatoid Arthritis and Cardiovascular Diseases.

Guo Y, Chung W et al.

J Am Heart Assoc

Patients with rheumatoid arthritis (RA) have a 2- to 10-fold increased risk of cardiovascular diseas...

Hypertension

459138

Participants

N/A

Studies

Details PubMed

GWAS 2023-11-06

Genome-Wide Association Study of Cardiovascular Resilience Identifies Protective Variation in the <i>CETP</i> Gene.

Yu C, Bakshi A et al.

J Am Heart Assoc

Background The risk of atherosclerotic cardiovascular disease (ASCVD) increases sharply with age. So...

ASCVD risk score (Systematic Coronary Risk Evaluation 2-Older People-Lipid scores)

Replicated

25919

Participants

N/A

Studies

Details PubMed

GWAS 2023-10-27

Genome-Wide Association Study of Pericardial Fat Area in 28 161 UK Biobank Participants.

Salih A, Ardissino M et al.

J Am Heart Assoc

BACKGROUND Pericardial adipose tissue (PAT) is the visceral adipose tissue compartment surrounding t...

Pericardial fat

28161

Participants

N/A

Studies

Details PubMed

GWAS 2023-03-28

Unprocessed Red Meat and Processed Meat Consumption, Plasma Metabolome, and Risk of Ischemic Heart Disease: A Prospective Cohort Study of UK Biobank.

Dong X, Zhuang Z et al.

J Am Heart Assoc

Background The evidence is equivocal on the association between meat consumption and ischemic heart ...

Red meat related metabolomic signature

92246

Participants

N/A

Studies

Details PubMed

GWAS 2023-01-31

Genetic Variants Associated With Systolic Blood Pressure in Children and Adolescents.

Pike MM, Schildcrout J et al.

J Am Heart Assoc

Background Genetics, along with lifestyle and behavioral characteristics, play an important role in ...

Childhood median systolic blood pressure percentile

9778

Participants

N/A

Studies

Details PubMed

GWAS 2022-10-31

Circulating Soluble CD163, Associations With Cardiovascular Outcomes and Mortality, and Identification of Genetic Variants in Older Individuals: The Cardiovascular Health Study.

Durda P, Raffield LM et al.

J Am Heart Assoc

Background Monocytes/macrophages participate in cardiovascular disease. CD163 (cluster of differenti...

Soluble CD163 levels

Replicated

3777

Participants

N/A

Studies

Details PubMed

GWAS 2022-10-04

Lipidome- and Genome-Wide Study to Understand Sex Differences in Circulatory Lipids.

Tabassum R, Ruotsalainen S et al.

J Am Heart Assoc

Background Despite well-recognized differences in the atherosclerotic cardiovascular disease risk be...

Phosphatidylinositol (16:0_18:2) levels

4642

Participants

N/A

Studies

Details PubMed

GWAS 2022-05-27

Genetic Architecture of Plasma Alpha-Aminoadipic Acid Reveals a Relationship With High-Density Lipoprotein Cholesterol.

Shi M, Wang C et al.

J Am Heart Assoc

Background Elevated plasma levels of alpha-aminoadipic acid (2-AAA) have been associated with the de...

alpha-Aminoadipic acid levels

5454

Participants

N/A

Studies

Details PubMed

GWAS 2022-04-26

Weak Association Between Genetic Markers of Hyperuricemia and Cardiorenal Outcomes: Insights From the STANISLAS Study Cohort With a 20-Year Follow-Up.

Kanbay M, Xhaard C et al.

J Am Heart Assoc

Background Hyperuricemia is associated with poor cardiovascular outcomes, although it is uncertain w...

Serum uric acid levels

1573

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Genomic Exploration of Essential Hypertension in African-Brazilian Quilombo Populations: A Comprehensive Approach With Pedigree Analysis and Family-Based Association Studies.

Borges VM, Horimoto ARVR et al.

J Am Heart Assoc

Essential hypertension

2025-03-21

Genome-Wide Search for Nonadditive Allele Effects Identifies PSKH2 as Involved in the Variability of Factor V Activity.

Gendre B, Martinez-Perez A et al.

J Am Heart Assoc

Plasma factor V levels (parent of origin effect)

2024-10-18

Chromosome 10q24.32 Variants Associate With Brain Arterial Diameters in Diverse Populations: A Genome-Wide Association Study.

Liu M, Khasiyev F et al.

J Am Heart Assoc

Global brain arterial diameters

2023-12-01

Genome-Wide Assessment of Shared Genetic Architecture Between Rheumatoid Arthritis and Cardiovascular Diseases.

Guo Y, Chung W et al.

J Am Heart Assoc

Hypertension

2023-11-10

Genome-Wide Association Study of Cardiovascular Resilience Identifies Protective Variation in the <i>CETP</i> Gene.

Yu C, Bakshi A et al.

J Am Heart Assoc

ASCVD risk score (Systematic Coronary Risk Evaluation 2-Older People-Lipid scores)

2023-11-06

Genome-Wide Association Study of Pericardial Fat Area in 28 161 UK Biobank Participants.

Salih A, Ardissino M et al.

J Am Heart Assoc

Pericardial fat

2023-10-27

Unprocessed Red Meat and Processed Meat Consumption, Plasma Metabolome, and Risk of Ischemic Heart Disease: A Prospective Cohort Study of UK Biobank.

Dong X, Zhuang Z et al.

J Am Heart Assoc

Red meat related metabolomic signature

2023-03-28

Genetic Variants Associated With Systolic Blood Pressure in Children and Adolescents.

Pike MM, Schildcrout J et al.

J Am Heart Assoc

Childhood median systolic blood pressure percentile

2023-01-31

Circulating Soluble CD163, Associations With Cardiovascular Outcomes and Mortality, and Identification of Genetic Variants in Older Individuals: The Cardiovascular Health Study.

Durda P, Raffield LM et al.

J Am Heart Assoc

Soluble CD163 levels

2022-10-31

Lipidome- and Genome-Wide Study to Understand Sex Differences in Circulatory Lipids.

Tabassum R, Ruotsalainen S et al.

J Am Heart Assoc

Phosphatidylinositol (16:0_18:2) levels

2022-10-04

Genetic Architecture of Plasma Alpha-Aminoadipic Acid Reveals a Relationship With High-Density Lipoprotein Cholesterol.

Shi M, Wang C et al.

J Am Heart Assoc

alpha-Aminoadipic acid levels

2022-05-27

Weak Association Between Genetic Markers of Hyperuricemia and Cardiorenal Outcomes: Insights From the STANISLAS Study Cohort With a 20-Year Follow-Up.

Kanbay M, Xhaard C et al.

J Am Heart Assoc

Serum uric acid levels

2022-04-26