Active: Accelerated cognitive decline Clear all

GWAS 2024-01-31

Disentangling Accelerated Cognitive Decline from the Normal Aging Process and Unraveling Its Genetic Components: A Neuroimaging-Based Deep Learning Approach.

Dai Y, Hsu YC et al.

J Alzheimers Dis

The progressive cognitive decline, an integral component of Alzheimer's disease (AD), unfolds in tan...

Accelerated cognitive decline

1064

Participants

N/A

Studies

Details PubMed

GWAS 2021-05-21

Genome-wide analysis identifies a novel LINC-PINT splice variant associated with vascular amyloid pathology in Alzheimer's disease.

Reddy JS, Allen M et al.

Acta Neuropathol Commun

Cerebral amyloid angiopathy (CAA) contributes to accelerated cognitive decline in Alzheimer's diseas...

Cerebral amyloid angiopathy in APOEe4 carrier Alzheimer’s disease

534

Participants

N/A

Studies

Details PubMed

GWAS 2019-11-23

Genome-wide association study of hippocampal atrophy rate in non-demented elders.

Guo Y, Xu W et al.

Aging (Albany NY)

Hippocampal atrophy rate has been correlated with cognitive decline and its genetic modifiers are st...

Hippocampal atrophy rate

602

Participants

N/A

Studies

Details PubMed

GWAS 2017-04-23

Single-nucleotide polymorphisms are associated with cognitive decline at Alzheimer's disease conversion within mild cognitive impairment patients.

Lee E, Giovanello KS et al.

Alzheimers Dement (Amst)

Introduction: The growing public threat of Alzheimer's disease (AD) has raised the urgency to quanti...

Accelerated cognitive decline after conversion of mild cognitive impairment to Alzheimer's disease (Alzhiemer's diagnosis trajectory interaction)

242

Participants

N/A

Studies

Details PubMed

GWAS 2015-08-11

GWAS of longitudinal amyloid accumulation on 18F-florbetapir PET in Alzheimer's disease implicates microglial activation gene IL1RAP.

Ramanan VK, Risacher SL et al.

Brain

Brain amyloid deposition is thought to be a seminal event in Alzheimer's disease. To identify genes ...

Longitudinal change in brain amyloid plaque burden

495

Participants

N/A

Studies

Details PubMed

Title

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Disease/Trait

Date

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Disentangling Accelerated Cognitive Decline from the Normal Aging Process and Unraveling Its Genetic Components: A Neuroimaging-Based Deep Learning Approach.

Dai Y, Hsu YC et al.

J Alzheimers Dis

Accelerated cognitive decline

2024-01-31

Genome-wide analysis identifies a novel LINC-PINT splice variant associated with vascular amyloid pathology in Alzheimer's disease.

Reddy JS, Allen M et al.

Acta Neuropathol Commun

Cerebral amyloid angiopathy in APOEe4 carrier Alzheimer’s disease

2021-05-21

Genome-wide association study of hippocampal atrophy rate in non-demented elders.

Guo Y, Xu W et al.

Aging (Albany NY)

Hippocampal atrophy rate

2019-11-23

Single-nucleotide polymorphisms are associated with cognitive decline at Alzheimer's disease conversion within mild cognitive impairment patients.

Lee E, Giovanello KS et al.

Alzheimers Dement (Amst)

Accelerated cognitive decline after conversion of mild cognitive impairment to Alzheimer's disease (Alzhiemer's diagnosis trajectory interaction)

2017-04-23

GWAS of longitudinal amyloid accumulation on 18F-florbetapir PET in Alzheimer's disease implicates microglial activation gene IL1RAP.

Ramanan VK, Risacher SL et al.

Brain

Longitudinal change in brain amyloid plaque burden

2015-08-11