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GWAS Study

Single-nucleotide polymorphisms are associated with cognitive decline at Alzheimer's disease conversion within mild cognitive impairment patients.

Lee E, Giovanello KS, Saykin AJ et al.

28560309 PubMed ID
GWAS Study Type
242 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

LE
Lee E
GK
Giovanello KS
SA
Saykin AJ
XF
Xie F
KD
Kong D
WY
Wang Y
YL
Yang L
IJ
Ibrahim JG
DP
Doraiswamy PM
ZH
Zhu H
Chapter II

Abstract

Summary of the research findings

Introduction: The growing public threat of Alzheimer's disease (AD) has raised the urgency to quantify the degree of cognitive decline during the conversion process of mild cognitive impairment (MCI) to AD and its underlying genetic pathway. The aim of this article was to test genetic common variants associated with accelerated cognitive decline after the conversion of MCI to AD.

242 European ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

242
Total Participants
GWAS
Study Type
No
Replicated
European
Ancestry
Canada, U.S.
Recruitment Country
Chapter IV

AI-Generated Summary

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