Active: Adenocarcinoma Clear all

GWAS 2025-07-01

Investigating the shared genetic architecture between adiposity measures and obesity-related cancers.

Wang S, Liu H et al.

Brief Bioinform

Fat distribution patterns are increasingly linked to obesity-related cancers; however, their shared ...

Leg fat ratio or ovarian cancer (pleiotropy)

127582

Participants

N/A

Studies

Details PubMed

GWAS 2025-05-08

Genome-wide association study for lung cancer in 6531 African Americans reveals new susceptibility loci.

Byun J, Han Y et al.

Hum Mol Genet

Despite lung cancer affecting all races and ethnicities, disparities are observed in incidence and m...

Lung adenocarcinoma

5274

Participants

N/A

Studies

Details PubMed

GWAS 2024-10-04

Multi-ancestry GWAS meta-analyses of lung cancer reveal susceptibility loci and elucidate smoking-independent genetic risk.

Gorman BR, Ji SG et al.

Nat Commun

Lung cancer remains the leading cause of cancer mortality, despite declining smoking rates. Previous...

Lung cancer

Replicated

260154

Participants

N/A

Studies

Details PubMed

GWAS 2023-05-26

Genome-wide association study of lung adenocarcinoma in East Asia and comparison with a European population.

Shi J, Shiraishi K et al.

Nat Commun

Lung adenocarcinoma is the most common type of lung cancer. Known risk variants explain only a small...

Lung adenocarcinoma

Replicated

172334

Participants

N/A

Studies

Details PubMed

GWAS 2023-05-18

Dissecting the genetic heterogeneity of gastric cancer.

Hess T, Maj C et al.

EBioMedicine

Gastric cancer (GC) is clinically heterogenous according to location (cardia/non-cardia) and histopa...

Gastric cancer

16814

Participants

N/A

Studies

Details PubMed

GWAS 2023-05-11

A Large-Scale Exome-Wide Association Study Identifies Novel Germline Mutations in Lung Cancer.

Shen S, Li Z et al.

Am J Respir Crit Care Med

Rationale: Genome-wide association studies have identified common variants of lung cancer. However, ...

Adenocarcinoma

Replicated

664374

Participants

N/A

Studies

Details PubMed

GWAS 2023-03-25

Genetic and non-genetic risk factors for early-onset pancreatic cancer.

Nodari Y, Gentiluomo M et al.

Dig Liver Dis

Early-onset pancreatic cancer (EOPC) represents 5-10% of all pancreatic ductal adenocarcinoma (PDAC)...

Early-onset pancreatic cancer

Replicated

11134

Participants

N/A

Studies

Details PubMed

GWAS 2022-07-26

GWAS meta-analysis of 16 790 patients with Barrett's oesophagus and oesophageal adenocarcinoma identifies 16 novel genetic risk loci and provides insights into disease aetiology beyond the single marker level.

Schröder J, Chegwidden L et al.

Gut

Objective: Oesophageal cancer (EC) is the sixth leading cause of cancer-related deaths. Oesophageal ...

Barrett's esophagus or Esophageal adenocarcinoma

49266

Participants

N/A

Studies

Details PubMed

GWAS 2021-07-03

Associations between pancreatic expression quantitative traits and risk of pancreatic ductal adenocarcinoma.

Pistoni L, Gentiluomo M et al.

Carcinogenesis

Pancreatic ductal adenocarcinoma (PDAC) is among the most lethal cancers. Its poor prognosis is pred...

Pancreatic ductal adenocarcinoma

Replicated

57497

Participants

N/A

Studies

Details PubMed

GWAS 2021-05-07

A genetic variant conferred high expression of CAV2 promotes pancreatic cancer progression and associates with poor prognosis.

Zhu Y, Tian J et al.

Eur J Cancer

Aim: This study aimed to identify the functional genes and genetic variants associated with the prog...

Pancreatic ductal adenocarcinoma

Replicated

1070

Participants

N/A

Studies

Details PubMed

GWAS 2021-05-03

Low frequency variants associated with leukocyte telomere length in the Singapore Chinese population.

Chang X, Gurung RL et al.

Commun Biol

The role of low frequency variants associated with telomere length homeostasis in chronic diseases a...

Telomere length

Replicated

25473

Participants

N/A

Studies

Details PubMed

GWAS 2021-02-11

Smoking modifies pancreatic cancer risk loci on 2q21.3.

Mocci E, Kundu P et al.

Cancer Res

Germline variation and smoking are independently associated with pancreatic ductal adenocarcinoma (P...

Pancreatic ductal adenocarcinoma x smoking interaction

19711

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Investigating the shared genetic architecture between adiposity measures and obesity-related cancers.

Wang S, Liu H et al.

Brief Bioinform

Leg fat ratio or ovarian cancer (pleiotropy)

2025-07-01

Genome-wide association study for lung cancer in 6531 African Americans reveals new susceptibility loci.

Byun J, Han Y et al.

Hum Mol Genet

Lung adenocarcinoma

2025-05-08

Multi-ancestry GWAS meta-analyses of lung cancer reveal susceptibility loci and elucidate smoking-independent genetic risk.

Gorman BR, Ji SG et al.

Nat Commun

Lung cancer

2024-10-04

Genome-wide association study of lung adenocarcinoma in East Asia and comparison with a European population.

Shi J, Shiraishi K et al.

Nat Commun

Lung adenocarcinoma

2023-05-26

Dissecting the genetic heterogeneity of gastric cancer.

Hess T, Maj C et al.

EBioMedicine

Gastric cancer

2023-05-18

A Large-Scale Exome-Wide Association Study Identifies Novel Germline Mutations in Lung Cancer.

Shen S, Li Z et al.

Am J Respir Crit Care Med

Adenocarcinoma

2023-05-11

Genetic and non-genetic risk factors for early-onset pancreatic cancer.

Nodari Y, Gentiluomo M et al.

Dig Liver Dis

Early-onset pancreatic cancer

2023-03-25

GWAS meta-analysis of 16 790 patients with Barrett's oesophagus and oesophageal adenocarcinoma identifies 16 novel genetic risk loci and provides insights into disease aetiology beyond the single marker level.

Schröder J, Chegwidden L et al.

Gut

Barrett's esophagus or Esophageal adenocarcinoma

2022-07-26

Associations between pancreatic expression quantitative traits and risk of pancreatic ductal adenocarcinoma.

Pistoni L, Gentiluomo M et al.

Carcinogenesis

Pancreatic ductal adenocarcinoma

2021-07-03

A genetic variant conferred high expression of CAV2 promotes pancreatic cancer progression and associates with poor prognosis.

Zhu Y, Tian J et al.

Eur J Cancer

Pancreatic ductal adenocarcinoma

2021-05-07

Low frequency variants associated with leukocyte telomere length in the Singapore Chinese population.

Chang X, Gurung RL et al.

Commun Biol

Telomere length

2021-05-03

Smoking modifies pancreatic cancer risk loci on 2q21.3.

Mocci E, Kundu P et al.

Cancer Res

Pancreatic ductal adenocarcinoma x smoking interaction

2021-02-11