Active: Alcohol consumption Clear all

GWAS 2025-06-13

Beyond volume: Unraveling the genetics of human brain geometry.

Primus SA, Hoffstaedter F et al.

Sci Adv

Brain geometry affects brain function. A quantitative encoding of form is provided by the Laplace-Be...

Left accumbens area shape (Laplace-Beltrami spectrum)

Replicated

24823

Participants

N/A

Studies

Details PubMed

GWAS 2025-05-07

Genome-wide analyses of variance in blood cell phenotypes provide new insights into complex trait biology and prediction.

Xiang R, Ben-Eghan C et al.

Nat Commun

Blood cell phenotypes are routinely tested in healthcare to inform clinical decisions. Genetic varia...

Red blood cell count variance

408068

Participants

N/A

Studies

Details PubMed

GWAS 2025-01-25

rs762855 single nucleotide polymorphism modulates the risk for diffuse-type gastric cancer in females: a genome-wide association study in the Korean population.

Park K, Shin CM et al.

Gastric Cancer

Intestinal-type gastric cancer (IGC) and diffuse-type gastric cancer (DGC) exhibit different prevale...

Diffuse gastric cancer

Replicated

1207

Participants

N/A

Studies

Details PubMed

GWAS 2024-06-13

Genome-wide analysis to assess if heavy alcohol consumption modifies the association between SNPs and pancreatic cancer risk.

Ni Z, Kundu P et al.

Cancer Epidemiol Biomarkers Prev

Pancreatic cancer is a leading cause of cancer-related death globally. Risk factors for pancreatic c...

Pancreatic cancer x heavy alcohol consumption interaction (1df)

10134

Participants

N/A

Studies

Details PubMed

GWAS 2024-03-13

Exploring the contribution of lifestyle to the impact of education on the risk of cancer through Mendelian randomization analysis.

Zagkos L, Schwinges A et al.

Sci Rep

Educational attainment (EA) has been linked to the risk of several types of cancer, despite having n...

Head and neck cancer

335709

Participants

N/A

Studies

Details PubMed

GWAS 2024-02-20

Interplay between Polygenic Variants Related Immune Response and Lifestyle Factors Mitigate the Chances of Stroke in a Genome-Wide Association Study.

Park S

Br J Nutr

We aimed to investigate the intricate interplay between genetic predisposition and lifestyle factors...

Stroke

58701

Participants

N/A

Studies

Details PubMed

GWAS 2024-02-20

Disentangling differing relationships between internalizing disorders and alcohol use.

Brasher MS, Grotzinger AD et al.

Am J Med Genet B Neuropsychiatr Genet

Both internalizing disorders and alcohol use have dramatic, wide-spread implications for global heal...

PHQ-9 questionnaire- trouble concentrating on things such as reading the newspaper or watching television several or more days in the last two weeks (UKB data field 20508)

139245

Participants

N/A

Studies

Details PubMed

GWAS 2024-01-26

Genetic architecture of alcohol consumption identified by a genotype-stratified GWAS and impact on esophageal cancer risk in Japanese people.

Koyanagi YN, Nakatochi M et al.

Sci Adv

An East Asian-specific variant on aldehyde dehydrogenase 2 (ALDH2 rs671, G>A) is the major geneti...

Daily alcohol intake in rs671 GG genotype

87980

Participants

N/A

Studies

Details PubMed

GWAS 2024-01-25

A Genome-Wide Association Study of Prostate Cancer Susceptibility Using Occupational and Environmental Factors as Confounding Factors.

Takeuchi T, Hattori-Kato M et al.

Cureus

Background In addition to genetic predisposition, occupational and environmental factors are importa...

Prostate cancer

714

Participants

N/A

Studies

Details PubMed

GWAS 2023-06-07

Genetic Underpinnings of the Transition From Alcohol Consumption to Alcohol Use Disorder: Shared and Unique Genetic Architectures in a Cross-Ancestry Sample.

Kember RL, Vickers-Smith R et al.

Am J Psychiatry

Objective: Recent genome-wide association studies (GWASs) of alcohol-related phenotypes have uncover...

Alcohol use disorder

393879

Participants

N/A

Studies

Details PubMed

GWAS 2023-04-07

Polygenic influences on the behavioral effects of alcohol withdrawal in a mixed-ancestry population from the collaborative study on the genetics of alcoholism (COGA).

Benca-Bachman CE, Bubier J et al.

Mol Cell Neurosci

Alcohol withdrawal (AW) is a feature of alcohol use disorder that may occur in up to half of individ...

Alcohol withdrawal factor score

8009

Participants

N/A

Studies

Details PubMed

GWAS 2022-10-03

Genome-Wide Investigation of Maximum Habitual Alcohol Intake in US Veterans in Relation to Alcohol Consumption Traits and Alcohol Use Disorder.

Deak JD, Levey DF et al.

JAMA Netw Open

Importance: Alcohol genome-wide association studies (GWASs) have generally focused on alcohol consum...

Maximum habitual alcohol consumption

247755

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Beyond volume: Unraveling the genetics of human brain geometry.

Primus SA, Hoffstaedter F et al.

Sci Adv

Left accumbens area shape (Laplace-Beltrami spectrum)

2025-06-13

Genome-wide analyses of variance in blood cell phenotypes provide new insights into complex trait biology and prediction.

Xiang R, Ben-Eghan C et al.

Nat Commun

Red blood cell count variance

2025-05-07

rs762855 single nucleotide polymorphism modulates the risk for diffuse-type gastric cancer in females: a genome-wide association study in the Korean population.

Park K, Shin CM et al.

Gastric Cancer

Diffuse gastric cancer

2025-01-25

Genome-wide analysis to assess if heavy alcohol consumption modifies the association between SNPs and pancreatic cancer risk.

Ni Z, Kundu P et al.

Cancer Epidemiol Biomarkers Prev

Pancreatic cancer x heavy alcohol consumption interaction (1df)

2024-06-13

Exploring the contribution of lifestyle to the impact of education on the risk of cancer through Mendelian randomization analysis.

Zagkos L, Schwinges A et al.

Sci Rep

Head and neck cancer

2024-03-13

Interplay between Polygenic Variants Related Immune Response and Lifestyle Factors Mitigate the Chances of Stroke in a Genome-Wide Association Study.

Park S

Br J Nutr

Stroke

2024-02-20

Disentangling differing relationships between internalizing disorders and alcohol use.

Brasher MS, Grotzinger AD et al.

Am J Med Genet B Neuropsychiatr Genet

PHQ-9 questionnaire- trouble concentrating on things such as reading the newspaper or watching television several or more days in the last two weeks (UKB data field 20508)

2024-02-20

Genetic architecture of alcohol consumption identified by a genotype-stratified GWAS and impact on esophageal cancer risk in Japanese people.

Koyanagi YN, Nakatochi M et al.

Sci Adv

Daily alcohol intake in rs671 GG genotype

2024-01-26

A Genome-Wide Association Study of Prostate Cancer Susceptibility Using Occupational and Environmental Factors as Confounding Factors.

Takeuchi T, Hattori-Kato M et al.

Cureus

Prostate cancer

2024-01-25

Genetic Underpinnings of the Transition From Alcohol Consumption to Alcohol Use Disorder: Shared and Unique Genetic Architectures in a Cross-Ancestry Sample.