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GWAS Study

rs762855 single nucleotide polymorphism modulates the risk for diffuse-type gastric cancer in females: a genome-wide association study in the Korean population.

Park K, Shin CM, Kim N et al.

39862296 PubMed ID
GWAS Study Type
1207 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

PK
Park K
SC
Shin CM
KN
Kim N
WS
Won S
SC
Song CH
OJ
Ohn JH
LS
Lee S
PJ
Park JH
YG
Yie GE
KS
Kang SJ
KJ
Kim JS
LD
Lee DH
Chapter II

Abstract

Summary of the research findings

Intestinal-type gastric cancer (IGC) and diffuse-type gastric cancer (DGC) exhibit different prevalence rates between sexes. While environmental factors like Helicobacter pylori infection and alcohol consumption contribute to these differences, they do not fully account for them, suggesting a role for host genetic factors.

115 Korean ancestry female cases aged < 50, 1,092 Korean ancestry female controls aged < 50

Chapter III

Study Statistics

Key metrics and study information

1207
Total Participants
GWAS
Study Type
Yes
Replicated
25 East Asian ancestry female cases, 2,832 East Asian ancestry female controls
Replication Participants
East Asian
Ancestry
Republic of Korea
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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