Active: Alcohol use disorder Clear all

GWAS 2023-08-15

Polygenic contributions to performance on the Balloon Analogue Risk Task.

Nurmi EL, Laughlin CP et al.

Mol Psychiatry

Risky decision-making is a common, heritable endophenotype seen across many psychiatric disorders. I...

Risky decision-making based on Balloon Analogue Risk Task (BART) performance

2072

Participants

N/A

Studies

Details PubMed

GWAS 2023-06-07

Genetic Underpinnings of the Transition From Alcohol Consumption to Alcohol Use Disorder: Shared and Unique Genetic Architectures in a Cross-Ancestry Sample.

Kember RL, Vickers-Smith R et al.

Am J Psychiatry

Objective: Recent genome-wide association studies (GWASs) of alcohol-related phenotypes have uncover...

Alcohol use disorder

393879

Participants

N/A

Studies

Details PubMed

GWAS 2023-05-08

Identifying Genetic Loci and Phenomic Associations of Substance Use Traits: A Multi-trait Analysis of GWAS (MTAG) study.

Xu H, Toikumo S et al.

Addiction

Background and aims: Genome-wide association studies (GWAS) of opioid use disorder (OUD) and cannabi...

Opioid use disorder (MTAG)

74635

Participants

N/A

Studies

Details PubMed

GWAS 2023-04-07

Polygenic influences on the behavioral effects of alcohol withdrawal in a mixed-ancestry population from the collaborative study on the genetics of alcoholism (COGA).

Benca-Bachman CE, Bubier J et al.

Mol Cell Neurosci

Alcohol withdrawal (AW) is a feature of alcohol use disorder that may occur in up to half of individ...

Alcohol withdrawal factor score

8009

Participants

N/A

Studies

Details PubMed

GWAS 2022-10-03

Genome-Wide Investigation of Maximum Habitual Alcohol Intake in US Veterans in Relation to Alcohol Consumption Traits and Alcohol Use Disorder.

Deak JD, Levey DF et al.

JAMA Netw Open

Importance: Alcohol genome-wide association studies (GWASs) have generally focused on alcohol consum...

Maximum habitual alcohol consumption

247755

Participants

N/A

Studies

Details PubMed

GWAS 2022-07-25

Genome-wide association study in individuals of European and African ancestry and multi-trait analysis of opioid use disorder identifies 19 independent genome-wide significant risk loci.

Deak JD, Zhou H et al.

Mol Psychiatry

Despite the large toll of opioid use disorder (OUD), genome-wide association studies (GWAS) of OUD t...

Opioid use disorder

554186

Participants

N/A

Studies

Details PubMed

GWAS 2022-07-11

Shared Genetics and Causality Between Decaffeinated Coffee Consumption and Neuropsychiatric Diseases: A Large-Scale Genome-Wide Cross-Trait Analysis and Mendelian Randomization Analysis.

Yin B, Wang X et al.

Front Psychiatry

Coffee or caffeine consumption has been associated with neuropsychiatric disorders, implying a share...

Decaffeinated coffee consumption and/or alcohol use disorder score

451275

Participants

N/A

Studies

Details PubMed

GWAS 2022-06-22

Genome-wide association study for circulating FGF21 in patients with alcohol use disorder: Molecular links between the SNHG16 locus and catecholamine metabolism.

Ho MF, Zhang C et al.

Mol Metab

Objective: Alcohol consumption can increase circulating levels of fibroblast growth factor 21 (FGF21...

FGF21 levels in alcohol use disorder

442

Participants

N/A

Studies

Details PubMed

GWAS 2022-01-29

Genome-wide meta-analysis of alcohol use disorder in East Asians.

Zhou H, Kalayasiri R et al.

Neuropsychopharmacology

Alcohol use disorder (AUD) is a leading cause of death and disability worldwide. Genome-wide associa...

Alcohol use disorder

13551

Participants

N/A

Studies

Details PubMed

GWAS 2022-01-11

Genetic Variants Associated with Acamprosate Treatment Response in Alcohol Use Disorder Patients: A Multiple Omics Study.

Ho MF, Zhang C et al.

Br J Pharmacol

Background and purpose: Acamprosate is an anti-craving drug used for the pharmacotherapy of alcohol ...

Plasma alpha aminoadipic acid levels in alcohol use disorder treated with acamprosate

442

Participants

N/A

Studies

Details PubMed

GWAS 2021-09-17

The Aldehyde Dehydrogenase ALDH2*2 Allele, Associated with Alcohol Drinking Behavior, Dates Back to Prehistoric Times.

Lin CL, Chien RN et al.

Biomolecules

Human alcohol-consumption behavior is partly genetically encoded. The alcohol consumption of 987 res...

Hazardous alcohol drinking

197

Participants

N/A

Studies

Details PubMed

GWAS 2021-08-20

Multi-omics integration analysis identifies novel genes for alcoholism with potential overlap with neurodegenerative diseases.

Kapoor M

Nat Commun

Alcohol use disorder

235610

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Polygenic contributions to performance on the Balloon Analogue Risk Task.

Nurmi EL, Laughlin CP et al.

Mol Psychiatry

Risky decision-making based on Balloon Analogue Risk Task (BART) performance

2023-08-15

Genetic Underpinnings of the Transition From Alcohol Consumption to Alcohol Use Disorder: Shared and Unique Genetic Architectures in a Cross-Ancestry Sample.

Kember RL, Vickers-Smith R et al.

Am J Psychiatry

Alcohol use disorder

2023-06-07

Identifying Genetic Loci and Phenomic Associations of Substance Use Traits: A Multi-trait Analysis of GWAS (MTAG) study.

Xu H, Toikumo S et al.

Addiction

Opioid use disorder (MTAG)

2023-05-08

Polygenic influences on the behavioral effects of alcohol withdrawal in a mixed-ancestry population from the collaborative study on the genetics of alcoholism (COGA).

Benca-Bachman CE, Bubier J et al.

Mol Cell Neurosci

Alcohol withdrawal factor score

2023-04-07

Genome-Wide Investigation of Maximum Habitual Alcohol Intake in US Veterans in Relation to Alcohol Consumption Traits and Alcohol Use Disorder.

Deak JD, Levey DF et al.

JAMA Netw Open

Maximum habitual alcohol consumption

2022-10-03

Genome-wide association study in individuals of European and African ancestry and multi-trait analysis of opioid use disorder identifies 19 independent genome-wide significant risk loci.

Deak JD, Zhou H et al.

Mol Psychiatry

Opioid use disorder

2022-07-25

Shared Genetics and Causality Between Decaffeinated Coffee Consumption and Neuropsychiatric Diseases: A Large-Scale Genome-Wide Cross-Trait Analysis and Mendelian Randomization Analysis.

Yin B, Wang X et al.

Front Psychiatry

Decaffeinated coffee consumption and/or alcohol use disorder score

2022-07-11

Genome-wide association study for circulating FGF21 in patients with alcohol use disorder: Molecular links between the SNHG16 locus and catecholamine metabolism.

Ho MF, Zhang C et al.

Mol Metab

FGF21 levels in alcohol use disorder

2022-06-22

Genome-wide meta-analysis of alcohol use disorder in East Asians.

Zhou H, Kalayasiri R et al.

Neuropsychopharmacology

Alcohol use disorder

2022-01-29

Genetic Variants Associated with Acamprosate Treatment Response in Alcohol Use Disorder Patients: A Multiple Omics Study.

Ho MF, Zhang C et al.

Br J Pharmacol

Plasma alpha aminoadipic acid levels in alcohol use disorder treated with acamprosate

2022-01-11

The Aldehyde Dehydrogenase ALDH2*2 Allele, Associated with Alcohol Drinking Behavior, Dates Back to Prehistoric Times.

Lin CL, Chien RN et al.

Biomolecules

Hazardous alcohol drinking

2021-09-17

Multi-omics integration analysis identifies novel genes for alcoholism with potential overlap with neurodegenerative diseases.

Kapoor M

Nat Commun

Alcohol use disorder

2021-08-20